DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and AgaP_AGAP004149

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_313033.3	Gene:	AgaP_AGAP004149 / 1273976	VectorBaseID:	AGAP004149	Length:	543	Species:	Anopheles gambiae

Alignment Length:	340	Identity:	95/340 - (27%)
Similarity:	149/340 - (43%)	Gaps:	62/340 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TETGRPIIDFRGLNNGNQGCESGQTCCPKTEILQYPVQA----------------DNQPLPTECG 87
            |.|.:|::      ..|:..|:  |..|.||..|.|..|                .:||:
Mosquito   217 TTTRQPVL------GSNRLAET--TPLPTTEPPQPPTTAIPTTTELLTTVLPTVVPDQPM----- 268

  Fly    88 HVNRIGVGFTITNARDIAQK----GELPWMVALL---DSRSRLPLG-GGSLIT-RDVVLTSSTKT 143
             :|....|.:: |.|.|..:    |:.|||..|.   .:..|:... .||||| |.|:..:...|
Mosquito   269 -INAPLCGLSV-NTRIIGGETEVPGQFPWMARLAYRNQTSGRVTYRCAGSLITNRHVITVAHCVT 331

  Fly   144 LEVPEKYLI-VRAGEWDFESITEERA---HEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLD 204
            ..:.|..|: :|.|:.:..::|:.|.   ::|.||.:|:.|.:..|...||:.||:.|....:..
Mosquito   332 NLIDELQLVSIRLGDLECNAVTDPRCSARYQDFAIEQIIPHESYDVPKYANDIALIKLRETTETY 396

  Fly   205 HHIGLICLP-----PPNRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPY 264
            :.|..:|||     |...|......|::|||..:...|:....|:.:.||:||.:.|    ...|
Mosquito   397 NIISPLCLPTDQYAPYALNLTGQLGIIAGWGSTSNRSNTPSPTLQWLRLPIVDTAGC----ANAY 457

  Fly   265 GK-------DFILDNSLICAGGEPGKDTCKGDGGAPLACPLQSDPNRYELLGIVNFG-FGCG-GP 320
            .:       ..|:..:.:||.|:..:|.|:||.|.||.....|..:|:.|||:|:|| ..|| ..
Mosquito   458 ARYSVNSRNPIIVSGNQMCAQGQENRDACQGDSGGPLMNEAISTRDRFVLLGLVSFGPRTCGVSN 522

  Fly   321 LPAAYTDVSQIRSWI 335
            .|..||.:|....||
Mosquito   523 FPGVYTRISAYIDWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	76/258 (29%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	74/256 (29%)
AgaP_AGAP004149	XP_313033.3	CLIP	47..92	CDD:288855
		Tryp_SPc	281..537	CDD:214473	76/259 (29%)
		Tryp_SPc	282..537	CDD:238113	75/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910