DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and gprin3

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_017951795.1	Gene:	gprin3 / 101733019	XenbaseID:	XB-GENE-6468967	Length:	725	Species:	Xenopus tropicalis

Alignment Length:	551	Identity:	93/551 - (16%)
Similarity:	167/551 - (30%)	Gaps:	215/551 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LFCGGSMAKECVQRNRCRIGTETGRPIIDFRGLNNGNQGCESGQTCCPKTEIL----QYPVQADN 79
            |.|..:|..|..::       |:|..|..||              .|.:.|:|    ...::...
Frog    55 LICSSNMTSEQERQ-------ESGSGISSFR--------------TCNELELLPPLVPQAIKDSA 98

  Fly    80 QPLPT-ECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKT 143
            ||:.| :..:::..|....::.|:           ::|||.::    .......:|..|.:...:
Frog    99 QPISTIKNTYLSTDGNAVLLSKAQ-----------LSLLDEKT----ANDEKSVKDNTLVAPLVS 148

  Fly   144 LEV--------PEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARP 200
            .|.        ..|.|:....:...:|:.:.: ..|.::..:..|...|:.:|..||:.:
Frog   149 AEAGMQVSSDFKNKPLVESEPDKGLDSLLQNK-EADPSLPSLPTHKTESINSGTQNASTI----- 207

  Fly   201 LKLDHHIGLICLPPPNRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYG 265
                               |.:..:::..|:.|
Frog   208 -------------------IESEGVITAEGEST-------------------------------- 221

  Fly   266 KDFILDNSLICAGGEPGKDTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCGGPLPAAYTDVS- 329
            ||.|..|.  |......||..|.:..     .:::||                 |||:.:.::.
Frog   222 KDSITSNE--CHKLSFEKDKIKKENE-----EVETDP-----------------PLPSRFKEMGT 262

  Fly   330 ----QIRSWI--DNCIQA------EAVHYSPQL------------------------GNVGQSPA 358
                .:.:|.  |..:||      ::|..||.:                        ||.|.|
Frog   263 MTSFSLENWTTQDAEVQAVANVENKSVSTSPSILAAFLKANSPALKERQEQVCIIYQGNPGAS-- 325

  Fly   359 PLDRYIPNIGLE---TQN-------------------EVHSPVQGSLHNVVYQTGGVG------Y 395
            .|||  .|..|:   :||                   ::|:.....|....:|...:|      |
Frog   326 QLDR--ANFALQAQLSQNQLAPKLCFQAPDALSSQPLQMHTKSPPDLARPTFQHTEIGRNSQILY 388

  Fly   396 IRGM-GQGTAFQGPVQVGELIPNEGTVSGGLVYDSNEIQKFNQGGIYIPHVGQGNSDNRYYPNPE 459
            ...: |||..|:...|:....|:...::...||..| |:...|..   |......|:..::..||
Frog   389 RNEIEGQGLCFREMPQMQMASPSPILMNVKPVYQIN-IENSAQPK---PRTMDMYSEPSHFRAPE 449

  Fly   460 IGAVPVGNPIPNEGNAFGGRGYDFNEIQKHN 490
            |.         |:.......|.:  .||.||
Frog   450 IN---------NKSRLHHLSGVE--NIQLHN 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	32/246 (13%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	31/242 (13%)
gprin3	XP_017951795.1	GRIN_C	600..720	CDD:373668
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910