DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4793 and tmprss3

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	104/354 - (29%)
Similarity:	157/354 - (44%)	Gaps:	68/354 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGFSR-IQALFCGGSMAKECVQRNRCRIGTETGRPIIDFRG-------LNNGNQGCESGQTCCPK 67
            ||||. :.:::......:|..:|:...:     .|...|.|       |.|.::.|.||.....|
Frog   169 LGFSSYVSSIYLPVEAVEEQFRRHFVSV-----TPSPKFAGQTSLLQQLINPSEYCSSGNVITLK 228

  Fly    68 TEILQYPVQADNQPLPTECGHVNRIGVGFTITNAR----DIAQKGELPWMVALLDSRSRLPLGGG 128
            ..:               ||    :...:| ::||    :::..|:.||..:|:  ...:.|.||
Frog   229 CVV---------------CG----LRPSYT-SSARIVGGNVSAVGQWPWQASLV--FQGVHLCGG 271

  Fly   129 SLITRDVVLTSS--TKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANN 191
            ||||...::|::  ...|..|| :..|:.|:   .|...|.|...|.::||:.|:.......||:
Frog   272 SLITPQWIVTAAHCVYDLLYPE-WWRVQVGQ---VSQASESAQTAVPVQKIIYHSKYRSSTMAND 332

  Fly   192 AALLFLARPLKLDHHIGLICLPPPNRNFIHNR-CIVSGWGK-----KTALDNSYMNILKKIELPL 250
            .||:.||.|...:..|..||||....:|...: |.:||||.     .|:....|..:      ||
Frog   333 IALIRLASPFTFNGSIQPICLPNYREDFPEGKICWISGWGATEEGGDTSQTMDYAGV------PL 391

  Fly   251 VDRSVCQTKLQGPYGKDFILDNSLICAGG-EPGKDTCKGDGGAPLACPLQSDPNRYELLGIVNFG 314
            :...||.||.  .||.  ::..|::|||. |.|.|||:||.|.||||   .|.|.::|:|..::|
Frog   392 ISNRVCNTKY--IYGG--VIKPSMVCAGFLEGGVDTCQGDSGGPLAC---EDSNVWKLMGTTSWG 449

  Fly   315 FGCG-GPLPAAYTDVSQIRSWIDNCIQAE 342
            .||. ...|..||.:|....||.  ||.|
Frog   450 IGCALRYKPGVYTRISSFLDWIH--IQME 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	81/241 (34%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	79/239 (33%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055	17/90 (19%)
		Tryp_SPc	244..472	CDD:238113	80/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910