DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4793 and tmprss9

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	334	Identity:	91/334 - (27%)
Similarity:	144/334 - (43%)	Gaps:	71/334 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 GLNNGNQGCESGQTCCPKTE-ILQYPVQADN--------QPLPTECG------HVNRIGVGFTIT 99
            ||.:|:  |.:....|..|: |::...:.||        ......||      ..|||..|...|
Frog   180 GLKSGS--CPAQVFACKNTQCIVKQNPECDNIRDCKDGSDEKNCNCGTRPAMQKTNRIVGGSDAT 242

  Fly   100 NARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEWDFES-- 162
                   |||.||.|:|.::....   .|:.:..|..|.|:.....             ||:.
Frog   243 -------KGEFPWQVSLRENNEHF---CGATVIGDKWLVSAAHCFN-------------DFQDPA 284

  Fly   163 ------ITEERAHED-----VAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLPPPN 216
                  .|...:..|     ..||.|::|.:...:....:.|:|.|..|||.:.:...:|||.|.
Frog   285 VWVAYIATTSLSGTDSSTVKATIRNIIKHPSYDPDTADYDVAVLELDSPLKFNKYTQPVCLPDPT 349

  Fly   217 RNF-IHNRCIVSGWG--KKTALDNSYM-NILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICA 277
            ..| :..:||::|||  |:   ||... .:|:|..:.::|:|:|.:....      ::...::||
Frog   350 HVFPVGKKCIITGWGYLKE---DNLVKPEVLQKATVAIMDQSLCNSLYSN------VVTERMLCA 405

  Fly   278 GGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCG-GPLPAAYTDVSQIRSWIDNCIQ 340
            |...|| |:|:||.|.||.|  :....::.|.|||::|.||. ...|..|..||:||:||.:.|
Frog   406 GYLEGKIDSCQGDSGGPLVC--EEPSGKFFLAGIVSWGVGCAEARRPGVYVRVSKIRNWILDII- 467

  Fly   341 AEAVHYSPQ 349
            :.:|...||
Frog   468 SSSVAADPQ 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	71/250 (28%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	69/248 (28%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060	6/34 (18%)
		Tryp_SPc	234..463	CDD:214473	73/262 (28%)
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060
		Tryp_SPc	919..1145	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910