DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4793 and klkb1

DIOPT Version :9

Sequence 1:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	392	Identity:	111/392 - (28%)
Similarity:	167/392 - (42%)	Gaps:	96/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 AKECVQRNRCRIGTETGRPIIDFRGLNNGNQ-------GCESGQTCCPKT----------EIL-- 71
            :||.:|||.|.|.|.| :.|.| .|:|..:.       .|:...:.||.|          |:|
Frog   246 SKEPLQRNVCYIRTST-KGIPD-EGINKEHTISGFSLLSCKFSPSVCPLTILSDAEFLGDELLVE 308

  Fly    72 ------------------QY----PVQA-------------DNQPLPTECGHVN--------RI- 92
                              |:    |:|:             .:..|||...|.|        |:
Frog   309 EVSGEKECQQECTNNIRCQFFTYRPMQSGCSENKCKCHMKISSNGLPTGIRHGNGEISGFSLRLC 373

  Fly    93 ------GVGFTITNARDI-----AQKGELPWMVAL---LDSRSRLPLGGGSLITRDVVLTSS--T 141
                  |.|..|.:|..|     :..||.||.|::   |.:..:....|||:|:...::|::  .
Frog   374 KIKSVKGCGEPIEHANRIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCF 438

  Fly   142 KTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHH 206
            ....:|:.: |:.:|.....:||:.....:.  .:|:.|.:.:......:.|||.|..|:..:.|
Frog   439 AMHPLPQMW-IIYSGVVKLSNITQSTPFSET--EQIIIHPHYTGAGNGTDIALLKLKTPISFNDH 500

  Fly   207 IGLICLPPPNRNFI-HNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYGKDFIL 270
            ...|||||....|: .|.|.::||| .|....|..|||:|.|:|.:....|    ||.|.:..|
Frog   501 QKAICLPPREPTFVLPNSCWITGWG-FTEESGSLANILQKAEVPQISTEEC----QGNYEQTRI- 559

  Fly   271 DNSLICAGGEPGK-DTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCGGP-LPAAYTDVSQIRS 333
            |..::|||.:.|| |:||||.|.||||.:.   ..:.|.||.::|.||..| .|..||.||:...
Frog   560 DKKILCAGYKRGKIDSCKGDSGGPLACVVD---EIWYLTGITSWGEGCARPGKPGVYTRVSEFTD 621

  Fly   334 WI 335
            ||
Frog   622 WI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	78/239 (33%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	76/237 (32%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519	13/38 (34%)
		APPLE	290..373	CDD:128519	14/82 (17%)
		Tryp_SPc	391..626	CDD:238113	79/245 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910