Protein Alignment CG31821 and CTSA

DIOPT Version :9

• Sequence 1: NP_001285968.1
• Gene: CG31821 / 34938
• FlyBaseID: FBgn0051821
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001161066.1
• Gene: CTSA / 5476
• HGNCID: 9251
• Length: 481
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 110/476 - (23%)
• Similarity: 184/476 - (38%)
• Gaps: 106/476 - (22%)

  Fly     6 LSIVCLIFLFGISEARKGFGPGEQD-----------------WGYVDVRDGAHMFYWLYYTTANV 53
            |.::.|:.|..:|.|.:|....:||                 .||:......|:.||.      |
Human    27 LFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWF------V 85

  Fly    54 SSYTD---RPLVLWLQGGPGGSSTALGNFQELGPVDTNGQPRDGNWVQYVNVLFIDNPVGSGFSY 115
            .|..|   .|:||||.||||.||.. |...|.||            ....|||::::|.|.||||
Human    86 ESQKDPENSPVVLWLNGGPGCSSLD-GLLTEHGP------------FLIANVLYLESPAGVGFSY 137

  Fly   116 ADNTSLLVTNNEELIDDLISFMLHFYKLHKEFKNVPLHIFSESYGGKMAPALAIRLAKAMSAGEL 180
            :|: ....||:.|:.......:..|::|..|:||..|.:..|||.|...|.||:.:.:..|.
Human   138 SDD-KFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSM--- 198

  Fly   181 AHPGTLKSVTIGNPWISTRHISREHSKYLFVNGLIDEDGVALLDAQEERILSALKKHEFDKATDE 245
                .|:.:.:||...|..........:.:.:||:   |..|..:.:....|..|.:.:|....|
Human   199 ----NLQGLAVGNGLSSYEQNDNSLVYFAYYHGLL---GNRLWSSLQTHCCSQNKCNFYDNKDLE 256

  Fly   246 YLRWYELMQQLTGE--IYLYN--------TQTHVDPSEDR--TYGYGEEFIRF-IERNVSEALQI 297
            .:...:.:.::.|.  :.:||        ..:|....:|.  ....|..|.|. ::|...:||..
Human   257 CVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLR 321

  Fly   298 NG-----------TVYAS---------------------QVMEVLSSLHGDRLKSEINT-IPRLL 329
            :|           |..||                     .:...|.:|...||...:|: ..:||
Human   322 SGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLL 386

  Fly   330 NETSVKVNIYSGQLDTLVPTTATLALIKDWAWNDKSEYLEANRTTIVIK-----GILQGYKKVGG 389
            :....::.:|:|.:|     .|...:..:|..:..::.:|..|...::|     ..:.|:.|...
Human   387 SSQKYQILLYNGDVD-----MACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFS 446

  Fly   390 NFGMYWINRSGHMAPSDNPVA 410
            :.....|..:|||.|:|.|:|
Human   447 HIAFLTIKGAGHMVPTDKPLA 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31821	NP_001285968.1	Peptidase_S10	26..417	CDD:298660	104/456 (23%)
CTSA	NP_001161066.1	Peptidase_S10	57..477	CDD:278857	102/446 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2160
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860