DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31821 and sxa2

DIOPT Version :9

Sequence 1:	NP_001285968.1	Gene:	CG31821 / 34938	FlyBaseID:	FBgn0051821	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_593043.1	Gene:	sxa2 / 2541701	PomBaseID:	SPAC1296.03c	Length:	507	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	112/461 - (24%)
Similarity:	188/461 - (40%)	Gaps:	101/461 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GYVDVRDGAHMFYWLYYTTANVSSYTDRPLVLWLQGGPGGSSTALGNFQELGPVD-TNGQPRDG- 94
            ||::......:||  .|..|.|.|.|   .::|||||||.:.| ||.|.|.||:: :...|...
pombe    77 GYLEANSDKSLFY--TYAPAVVDSET---FIVWLQGGPGCAGT-LGFFSENGPIEISQSSPSPSL 135

  Fly    95 ---NWVQYVNVLFIDNPVGSGFSYADNTSLLVTNNEELIDDLISFMLHFYKLHKEFKNVPLHIFS 156
               :|..:.|:|::|.|.|:|  |:...:...|..||...|.::.:..||:.........|::..
pombe   136 NPESWTNFANMLWLDQPFGTG--YSQGQAAYTTTIEEASSDFVNALKSFYQKFPHLMKKKLYLVG 198

  Fly   157 ESYGGKMA----------PALAIR-LAKAMSAGELAHPGTLKSVTIGNPWISTRHISREHSKYLF 210
            ||||...:          |:|.|. :...:.:|..|...|.:.:| .:.|:  .|||:  ..|.|
pombe   199 ESYGSIWSANFAEALLSEPSLNINFMGVGIVSGLTADYETQEQIT-ASIWV--EHISK--LGYYF 258

  Fly   211 VN---GLIDEDGVALLDAQEERILSALK---------KHEFDKATDEYLRWYELMQQLTGE---- 259
            .|   .:.:|......:.|.:.:|:.|.         :.|::.:|...||..|   .|.||
pombe   259 NNTSSTISEEFKKRNKECQYDSVLNRLTFPTEQYPIWRPEYNFSTSTSLRKRE---ALDGEDIGN 320

  Fly   260 -----------------IYLYNT-QTHVDPSEDRTYG-YGEEFIRFIERNVSEALQINGTVYASQ 305
                             :||.|: ....|.|.|.::. |.:..|.::.|.     .:..:::|::
pombe   321 VFNSISGCDLYSLSNFLLYLENSCVITYDVSLDCSFNEYNDPLITYLNRE-----DVRSSLHATK 380

  Fly   306 VMEVLSSLHG--------DRLKSEINT---------IPRLLNETSVKVNIYSGQLDTLVPTTATL 353
            ....|:|..|        |..|..::.         ||||..:  .||:..:|.||..:..|.||
pombe   381 ASTALTSGEGVFADGCNFDLYKKIVSNNVESVLVEIIPRLTEK--YKVSFLAGALDLQILWTGTL 443

  Fly   354 ALIKDWAWNDKSEYLEANRTTIVIKGILQ---GYKKVGGNFGMYWINRSGHMAPSDNPVAMQYVL 415
            ..:::..||....:.::       .|.|:   |:.....|......|..||||||.:|..::..|
pombe   444 LALQNTTWNGWQGFTQS-------PGSLETTNGFTLDERNLAFTLSNSVGHMAPSKDPQMVREWL 501

  Fly   416 QSVTQY 421
            ::...|
pombe   502 ENTLLY 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31821	NP_001285968.1	Peptidase_S10	26..417	CDD:298660	111/455 (24%)
sxa2	NP_593043.1	Kex1	1..507	CDD:225490	111/459 (24%)
sxa2	NP_593043.1	Peptidase_S10	65..503	CDD:298660	111/455 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I1757
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11802
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050