DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31821 and Y16B4A.2

DIOPT Version :9

Sequence 1:	NP_001285968.1	Gene:	CG31821 / 34938	FlyBaseID:	FBgn0051821	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_510452.4	Gene:	Y16B4A.2 / 181572	WormBaseID:	WBGene00012445	Length:	2161	Species:	Caenorhabditis elegans

Alignment Length:	496	Identity:	119/496 - (23%)
Similarity:	194/496 - (39%)	Gaps:	146/496 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GYVDVRDGAHMFYWLYYTTANVSSYTDRPLVLWLQGGPGGSSTALGNFQELGPVDTNGQPRDG-- 94
            ||::..| .|.|::.:..:.|  ..|:.|::|||.||| |||:..|...|.||...|   :||
Worm   533 GYLNASD-THRFHYWFVESQN--DPTNSPVLLWLNGGP-GSSSLWGMLTENGPFRPN---KDGQT 590

  Fly    95 ------NWVQYVNVLFIDNPVGSGFSYA----DNT---SLLVTNNEELIDDLISFMLHFYKLHKE 146
                  :|.::.|||::::|...|:||:    |.|   .|..::|...:.|.      |..:..:
Worm   591 LYENVHSWNKFANVLYLESPHQVGYSYSTVANDYTYGDDLTASDNYNALKDF------FNNIFPQ 649

  Fly   147 FKNVPLHIFSESYGGKMAPALAIRLAKAMSAGELAHPGTLKSVTIGNPWISTRHISREHSKYLFV 211
            :|..|.:|..|||||...|.|:..|.:.:||||:..  ..|.:.|||..::|:.........|:.
Worm   650 YKQNPFYITGESYGGVYIPTLSKLLLQMLSAGEINI--NFKGIAIGNGELTTKLQVNSAIFQLYT 712

  Fly   212 NGLIDEDGVALLDAQ------------------------------------EERILSALKKHEFD 240
            .||..|:....|.|:                                    ...||..:....::
Worm   713 YGLFGENEYNALVARCCKNVTDPTQCDFYTPYVFFDYLGNYKAVDGADPFCSSTILGVVNDQVWN 777

  Fly   241 KATDEYLRWYELMQQLTGEIYL------------YNTQTHV--------------DP-------S 272
            .|.:.|        .:.|:.|.            .|.|...              ||       |
Worm   778 SANNPY--------NIYGDCYTTSASSSSSSSSKSNKQNRAAVRDNAGLLNLASSDPFDGFPCWS 834

  Fly   273 EDRTYGYGEEFIRFIER-NVSEALQINGTV--YASQVMEVLSSLHGDRLKSEINTI-PRLLN--- 330
            .|.|..|       :.| :|..||.|..||  :.|....|.:.|: :|...|::.: .|:|:
Worm   835 TDATTTY-------LNRDDVRNALHIPTTVQQWQSFNQTVNAQLY-NRSYFELDAVLNRILSSYY 891

  Fly   331 --ETSVKVNIYSGQLDT---------LVPTTATLALIKDWA----WNDKSEYLEANRTTIVIKGI 380
              :.::|:.||:|.:|.         |:...|:.|.:|..:    ||    |:.|.:..:   ..
Worm   892 YKQNNMKILIYNGDVDMVCNHLGDQWLIEQVASNAGLKTVSPRQPWN----YVMAGQNYL---PQ 949

  Fly   381 LQGYKKV-GGNFGMYWINRSGHMAPSDNP-VAMQYVLQSVT 419
            |.||.|| ..|..:..:..|||:.|.|.| .|:|.:...::
Worm   950 LAGYVKVFDSNLNLVTVKGSGHLVPQDRPGPALQMIFNFIS 990

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31821	NP_001285968.1	Peptidase_S10	26..417	CDD:298660	119/492 (24%)
Y16B4A.2	NP_510452.4	Peptidase_S10	38..480	CDD:298660
		Peptidase_S10	520..991	CDD:278857	119/496 (24%)
		Peptidase_S10	1087..1572	CDD:278857
		Peptidase_S10	1610..2061	CDD:278857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2939
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810