Protein Alignment Tep1 and a2m3f

DIOPT Version :10

• Sequence 1: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_068074598.2
• Gene: a2m3f / 793100
• ZFINID: ZDB-GENE-070705-476
• Length: 1457
• Species: Danio rerio
• Alignment Length: 1486
• Identity: 371/1486 - (24%)
• Similarity: 614/1486 - (41%)
• Gaps: 273/1486 - (18%)

  Fly    22 LYSVLAPKTLRSNSAYNVVVAIHNTTRTTEVSVSLTGPSLNSRKYVDVQSMSSKSVR---FDIPK 83
            |:.|..|..:.|.|...:..::.....:..::::|.... |:...:..|:...|..|   |..|
Zfish    48 LFLVTFPSLIESGSGAKLCASLLKPQGSLTITITLIDDK-NTETQLARQTTQRKLHRCFNFQAP- 110

  Fly    84 LTEGD--YELKVMGSG-GIEFQNSTKLSFAPDLNWLYIQSDKATYKPGDKIQFRVLFLDKNTRPA 145
            |..||  ..::|:..| ..:.....|:.|...|...:||:||..|.||..:.|||:.:.....|
Zfish   111 LVNGDSVQTVRVVVQGQSFKMTEERKVMFRSYLPLTFIQTDKPLYNPGQTVNFRVVTMSDKLVP- 174

  Fly   146 VIDKPIKIEIRDGDQNL-IKSWKDIKPAKGVYSGELQLSDRPVLGNWTVTATVQDEGKVTNVLVV 209
             :|:...:.:.:..:|: |..|.::.....:......|.....:|.:|:.|.:.|. .::....|
Zfish   175 -LDQMYNLVVLEDFRNIRINQWTNVSSVNWILELSHVLIPEAQVGTYTLRAYIGDR-IISQSFDV 237

  Fly   210 DKYVVPKFEVVVLTAKNVAASAGYIRATIKARYTFKKPVKGHVV--------------------- 253
            .:||:|||:|.|...:..:.:...::.....:|||.:||.|.|:
Zfish   238 KQYVLPKFDVTVNAPQTYSVADVGLKVEACGKYTFGQPVPGQVLVEVCRQPFTFAQDPKVTSICL 302

  Fly   254 ------------------ATIEGSSTEQSLPIDGEVNVEFPISATAKRLLKITAIVTEELTDIKH 300
                              ::..|:|.|.:|.....|||.                :|||.|.:..
Zfish   303 NKSTKTNNTGCASLTLSTSSFFGTSFESNLQNSFVVNVN----------------LTEEGTGVVM 351

  Fly   301 NGTAYVTVHQHRHKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPV-------MDSSKMVNFNVLCC 358
            :.:..|::.....|:..:..|..|..|.:...|..|.:.:|:|:       :|||...|..:...
Zfish   352 SKSTTVSITFEVGKVTFVDLPKFYNYGSTVNGKISVSDFNGNPIYSKAVYLLDSSIWPNKLLFNL 416

  Fly   359 QVSKN--------------------FSASLQNSIATEHIMLPETCQSCLVTSTF-DTAENIERYI 402
            ..:||                    .||:.|:..::.........|...::.|. ||....:..|
Zfish   417 TTNKNGFAKFSLDTTSFPKADLNLVASATPQSYFSSNSPYFTTDSQVVQLSQTDPDTPTFSDLSI 481

  Fly   403 YKLNKPLMIAINTKKPQLRKLLKINIISDTYLPYFILTVVARGNIVLSLFQEMKEKKKSQEIEFE 467
            .||.:||  ...|......|.|.:....| |....|..|::||.|||..|:.::.:..:...:..
Zfish   482 VKLEQPL--KCGTTYSVTVKYLFVGETGD-YSADIIYMVMSRGVIVLHGFKTVQARASNTLTKGT 543

  Fly   468 PTFAL------VPQATIFVHYIIDG-VLMSDEKTVDIERDFENTIEI-LTTNEALPRDEVSLKVK 524
            .||.|      .|...|.|:.::.. .:::...:.|.|:.|.|.:.: .:...|:|.:...|.|.
Zfish   544 VTFDLSVLAKMAPIVQILVYSVLPSQTVVTGSASFDTEKCFSNQVSLQFSPATAVPGEGNILTVS 608

  Fly   525 TNPHSFVGLLGVDQSVLLLRSGNDLNRD-----LILNNLATYSTDLVILTNANINIYRSSGGCYT 584
            ....|..||..:|||||:::||..|:.:     |.|.:|:.|........|. :|: |......|
Zfish   609 AQAGSLCGLSAIDQSVLIMQSGGRLSAEGVFNMLPLQSLSDYPYGAEDQQNC-LNV-RPRRAVPT 671

  Fly   585 NPGYTNCTGSLIGRTMFKNEPTKN----------------------------SG--PVPIVGSTR 619
            :..|.  |...:|..:..|.|.:.                            ||  |.|:..:..
Zfish   672 DQAYN--TFKSVGMKIATNLPVREPECLKFKDLLYYRNFHGVFPLREVAFAVSGKAPAPLAMAEM 734

  Fly   620 A--QASLPPVRKLFPETWLFSNITDVGANGEYIIKETVPDTLTSWVITGFSLSPQS-GLAVTRNP 681
            |  ..|...:|..|||||:: .::.||.:|...:..|||||:|:|....|.||... |||   .|
Zfish   735 AGTGGSSVTIRTYFPETWIW-QLSLVGDSGSTSVPLTVPDTITTWDTEAFCLSSNGFGLA---PP 795

  Fly   682 SRIRVFQPFFITTNLPYSVKRGEVIAIPVIVFNYLGMDVKAKVLMDNSDGQYEFIETTNKNVSQY 746
            :.:..|||||:...||||:.|||...:...|||||...:|              |:.|....|.|
Zfish   796 ALLTSFQPFFLELTLPYSIIRGEAFELVATVFNYLLQCLK--------------IQVTPTPSSNY 846

  Fly   747 -LRGVRRKKTLWIPANTGRGISFMIRPKKVGLTTLKITA----ISKYAGDR------------LH 794
             |..:..:.:..:..|..:.|.:.:....:|...:.|:|    ..:..||:            :.
Zfish   847 TLTPINDQSSSTLSTNWRKTIKWALTASVIGTVNVTISAEASPSQELCGDQDVTVSSRGRIDIVT 911

  Fly   795 QILKVEADGVQKYVNKAVLINVQRLNRRSLAPPEKTIIIEKA-----DNVIEGSETVEFEVCGTS 854
            :.|:|.|:||::           ...|..|..|:.:|:.|..     .|||:||.:....|.|..
Zfish   912 RSLRVLAEGVER-----------TFTRSWLLCPKGSILSESVKITLPTNVIQGSASCSVSVIGDI 965

  Fly   855 QAPQLEHLDDLVHLPCGCGEQNMFNFVPSILALSYLKAKNRQDQEIENKAKRYVETGYQIELNYK 919
            ....|.:|.:|:.:|.|||||||....|::..|.||....:....|::.|...:.||||.||||:
Zfish   966 MGRALNNLANLLQMPSGCGEQNMIILAPNVYILRYLTVTAQLTPAIQDTATSSLLTGYQGELNYR 1030

  Fly   920 RNDGSFSAWGQHDALGSTWLTAYVIRSFHQAAKYIDIDKNVLVAGLDFLVSRQSTDGKFKELGMV 984
            .:|||||.:|...:  :|||||:|:|:|..|..:..||.|||....|:|:|.|.:||.|.:.|.:
Zfish  1031 HSDGSFSTFGYDPS--NTWLTAFVMRTFGLARSFTYIDPNVLKGAKDWLISTQGSDGCFVQQGTL 1093

  Fly   985 IHNSH----GSPLALTSFVLLTFFENEEYMPKYKHVIDRAVEFVVTEVHQSNEPYDLAIAALALS 1045
            .||..    |..:.:|.:::.:..|..  :|....||.:|:.|:...|......|..|:.|...|
Zfish  1094 YHNDMKGGVGDNVTMTGYIVASLLEIG--VPVTDPVITKALSFLRPLVGNLGNTYVTALLAYTFS 1156

  Fly  1046 LA-RNRNAYKVLDKLDKLATRRGDHKWWTGSDKCKSSEVETTSYVLLALLEHNISDEP------- 1102
            || ......::|:.|...|...|....|:.:....:..||.::|||||:|    :.:|
Zfish  1157 LAGETSTRAQLLNSLRNTAISEGTTLHWSQTTSGDTLAVEISAYVLLAVL----TVQPVTTANLG 1217

  Fly  1103 --KPIVDWLISKRNSNGGFVSSQDTVVGIMALTKYELQSH--ASTEAIDIEFWHLNEDKKHVRVT 1163
              ..||:|:::::|..|||.|:|||||.:.||..|..|:.  ..:..:.::......|..:..||
Zfish  1218 YANRIVNWIVAQQNPYGGFSSTQDTVVALQALALYAAQAFTPGGSSTVTVQSSVPAGDNFNFAVT 1282

  Fly  1164 KENEFKVQTHQLPENTNEVKLLAKGQGRAQVQLTYRYNVATK-----------------EARP-S 1210
            ..|....|.:.|........::|:|...|.||:...||:.|.                 :|.| :
Zfish  1283 PNNRLLYQRNSLNNFPGTYNVVARGSACASVQVACFYNIPTPVMVARTLSVVAKVSGDCQAAPVN 1347

  Fly  1211 FKLTTTVKKSHKGRLILGICGTYTPIAASERNKTTNMALMQVQLPSGYVCDIE------PFADIE 1269
            ..||.|||              ||     .|..||||.|:.:::.||:..|..      .||.:
Zfish  1348 LMLTFTVK--------------YT-----GRKPTTNMVLVDIKVLSGFTADTSLLGSPPNFAPL- 1392

  Fly  1270 AISDVKRVETKNEDTEVHIYFEKLSPGDRKCLTLEAIYTHAVANLKPSWVRLYDYY 1325
                |:||::..:  .|.:|.:::..|.....:::.....||.||||:.:.:||||
Zfish  1393 ----VQRVDSNGD--HVLVYLQEVPKGVPVTFSIQLTRAVAVQNLKPAVINIYDYY 1442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep1	NP_523578.1	YfaS	<117..1200	CDD:441940	312/1234 (25%)
		A2M_2	859..1135	CDD:239227	99/289 (34%)
		A2M_recep	1243..1336	CDD:462226	26/89 (29%)
a2m3f	XP_068074598.2	None