Protein Alignment Tep1 and LOC1278851

DIOPT Version :10

• Sequence 1: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_318490.3
• Gene: LOC1278851 / 1278851
• VectorBaseID: AGAMI1_009766
• Length: 1333
• Species: Anopheles gambiae
• Alignment Length: 1412
• Identity: 370/1412 - (26%)
• Similarity: 662/1412 - (46%)
• Gaps: 143/1412 - (10%)

  Fly     1 MLWLILSSTILHCVLLSNANGLYSVLAPKTLRSNSAYNVVVAIHNTTRT-TEVSVSLTGPS---- 60
            ::|..:.|.||..:::..|.....|:.||.:|:|..|.:|::..|:.:| .::.|.|.|.:
Mosquito     5 IMWKCIRSRILMVIIVIGAAQGVLVVGPKYIRANQEYTLVISNINSNQTKLDLIVKLEGETDNGL 69

  Fly    61 --LNSRKYVDVQSMSSKSVRFDIPK-LTEGDYELKVMGSGGIEFQNSTKLSF-APDLNWLYIQSD 121
              ||..|..||:...::.:.|::|: |.||:|::.:.|..|..|.....|.: :..::.| ||.|
Mosquito    70 NVLNVTKTFDVRRNMNRMINFNMPENLAEGNYKITIDGQQGFSFHKEAALVYLSKSISGL-IQVD 133

  Fly   122 KATYKPGDKIQFRVLFLDKNTRPAVIDKPIKIEIRDGDQNLIKSWKDIKPAKGVYSGELQLSDRP 186
            |..:||||.:.|||:.||...:|....|.:.:.|||..:|:|:.|...|...||:.|.||::...
Mosquito   134 KPVFKPGDTVNFRVIVLDTELKPPARVKLVYVTIRDPQRNVIRKWSSAKLYTGVFEGYLQIAPTA 198

  Fly   187 VLGNWTVTATVQDEGKVTNVLVVDKYVVPKFEVVVLTAKNVAASAGYIRATIKARYTFKKPVKGH 251
            :||.|.:...|:.|..|:....|.:||:..|:|.|:.:.........:..||:|.|.|.|||:|
Mosquito   199 MLGIWNILVQVEGEELVSKTFEVKEYVLSTFDVQVMPSVIPLEEHQAVNLTIEAYYHFGKPVQG- 262

  Fly   252 VVATI------EGSSTEQSLPIDGEVNVE------FPISATAKRL-LKITAIVTEELTDIKHNGT 303
             ||.:      |....::.|.:.|:..||      |.:....:.: :|:|.|  |:.|:......
Mosquito   263 -VAKVELYLDDELIDQKKELTVYGKGQVELLFFGKFEMYEDQQDVRVKVTFI--EQYTNRTLVKL 324

  Fly   304 AYVTVHQHRHKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPVMDSSKMV--------------NFN 354
            :.:|:::|.:::|.:....|:.||:..:|.....:.||:|....:..|              |..
Mosquito   325 SQITIYKHAYRVEFIKESPHFHPGIPFKFVLQFTHHDGTPAKGITGKVEVSGIGFETTATSDNDG 389

  Fly   355 VLCCQVSKNFSASLQNSIATEHIMLPETCQSCLVTSTFDTAENIERYIYKLNKPLMIAINTKKP- 418
            ::..::.||      ..|.:.|:.....      ...|....|::|.::..|  ..|.|..|.|
Mosquito   390 LIKLELQKN------EDIESMHVSFVNN------NDGFVFEHNVDRDVFATN--AYIKIELKSPI 440

  Fly   419 QLRKLLKINIISDTYLPYFILTVVARGNIVLSLFQEMKEKKKSQEIEFEPTFALVPQATIFVHYI 483
            :|.|.::..:.....:.:|:..||::||||.:.|.. ..|:|...::.:.|..::|:|.|.|..:
Mosquito   441 KLNKNMRFTVTCTERMTFFVYYVVSKGNIVDAGFMR-PNKQKKYSLQLDATEKMIPKAKILVATL 504

  Fly   484 IDGVLMSDEKTVDIE-RDFENTIEI-LTTNEALPRDEVSLKVKTNPHSFVGLLGVDQSVLLLRSG 546
            ::..:::|  .|||: :.|.:..:: :...|.:|..::.|.:...|.::|||...|:::.|....
Mosquito   505 VNHTMVND--IVDIDFQGFRHNFDLSIDEQEIMPERQIELSMSGRPGAYVGLAAYDKALPLFNKN 567

  Fly   547 NDLN-RDL--ILNNLATYSTDLVILTNANINIYRSSGGCYTNPGYTNCTGSLIGR---TMF--KN 603
            :||. .|:  :.:...:|.|:       ..:::.:.|              |..|   .||  .|
Mosquito   568 HDLFWEDIGQVFDGFHSYDTN-------EFDLFHNMG--------------LFARMDNIMFDQSN 611

  Fly   604 EPTKNSGPVPIVGSTRAQASLPPVRKLFPETWLFSNITDVGANGEYIIKETVPDTLTSWVITGFS 668
            :.:..||         .||.....||.|.|:||:.... :|.:|...:.|.||||.|:|.:||||
Mosquito   612 DKSARSG---------QQADGTVFRKQFLESWLWKTAI-IGNSGTLKLIEVVPDTTTTWYLTGFS 666

  Fly   669 LSPQSGLAVTRNPSRIRVFQPFFITTNLPYSVKRGEVIAIPVIVFNYLGMDVKAKVLMDNSDGQY 733
            :.|..||.:.:.|..|...|||.:..:||||:||||.|.|..|:.:.|..:....|.:.|.:.:.
Mosquito   667 IDPVYGLGIVKKPIEITTVQPFVVMESLPYSIKRGEAIEIQFILISNLQEEYTVDVTLYNENNEM 731

  Fly   734 EFIETTNKNVSQYLRGVRRKKTLWIPANTGRGISFMIRPKKVG--LTTLKITAISKYAGDRLHQI 796
            ||:..:..|||.       .|::.:|...|:.:||:::.||:|  :..:|.:..::.|.|.|.::
Mosquito   732 EFLGRSISNVSY-------TKSVSVPPKVGKPVSFLVKAKKLGEMMVRVKASIANELATDALEKV 789

  Fly   797 LKVEADG-VQKYVNKAVLINVQRLNRRSLAPPEKTIIIEKADNVIEGSETVEFEVCGTSQAPQLE 860
            ::|..:. ||..|...........||..|..|.   |.:||||   ||..:|..:.........|
Mosquito   790 IRVTPESLVQSGVESFGFFMDTHQNRTFLVNPN---IDKKADN---GSIAIELRINPNLLIKVKE 848

  Fly   861 HLDDL-VHLPCGCGEQNMFNFVPSILALSYLKAKNRQDQEIENKAKRYVETGYQIELNYKRNDGS 924
            :|:|| ..|| .|  :|:.....:.....||.|.....|.:...|...:...|.:.:....:|.|
Mosquito   849 NLNDLHTALP-SC--RNVIRLGLNFAVADYLIACGLNAQNLPENAVDALSKEYMLLMTCLNSDSS 910

  Fly   925 FSAWGQHDALGSTWLTAYVIRSFHQAAKYIDIDKNV-LVAGLDFLVSRQSTDGKFKELGMVIHNS 988
            |.:  ..:.:.:.:.||:|..:...|.|.:....|| |....|:|.|||...|.|:|:...:|.:
Mosquito   911 FDS--VQNIVSNIFYTAFVANTLDTAPKNVRQTSNVKLEKAFDWLASRQQRFGSFREIESDLHYT 973

  Fly   989 HGSPLALTSFVLLTFFENEEYMPKYKHVIDRAVEFVVTEVHQSNEPYDLAIAALALSLARNRNAY 1053
            . |.:||||:||....|||....|:..||::.:.|:..:........||||...|:.|..:....
Mosquito   974 R-SEIALTSYVLAAMIENESAKVKHAVVIEKGMWFLSNQFDLITSANDLAIVTYAMMLYGHWRKD 1037

  Fly  1054 KVLDKLDKLA--TRRGDHKWWTGSDKCKSSEVETTSYVLLALLEHNISDEPKPIVDWLISKRNSN 1116
            ...:||..::  |..|..::|.     .|:.||.|||.||:.:..|......||:.||:::::..
Mosquito  1038 AAFEKLIDMSTITNNGAERYWN-----TSNSVEATSYALLSHVLVNKLLAALPIMRWLVNQKSEI 1097

  Fly  1117 GGFVSSQDTVVGIMALTKYELQSHASTEAIDIEFWHLNEDKKHVRVTKENEFK--VQTHQLPENT 1179
            ......:.|.:.:.||::...:...|.....::..:    |:..|:.:.:.::  :|....|::.
Mosquito  1098 DSVSGQETTYLRLKALSRMTKKISPSRNDYMVQLKY----KQSTRLLRFDSYRNMIQNITTPQDV 1158

  Fly  1180 NEVKLLAKGQGRAQVQLTYRYNVATKEARPSFKLTTTVKK-SHKGRLILGICGTYTPIAASERNK 1243
            .::|:..:|.|...:::.|:|.:........|:|....:. |....|.|.:|..|.|   :.|:.
Mosquito  1159 RKIKITVEGIGVGLLEVMYKYRLNLVNFEHRFQLDLQKQNTSSDNELRLNVCANYIP---TLRDS 1220

  Fly  1244 TTNMALMQVQLPSGYVCDIEPFADIEAISDVKRVETKNEDTEVHIYFEKLSPGDRKCLTLEAIYT 1308
            .:||.|::|.||||||.|..|.::...::.::.:|.:...|.|.:|:..:.. :|.|.|:.|...
Mosquito  1221 HSNMTLIEVTLPSGYVVDRNPISEQTTVNPIQNMEIRYGGTSVVLYYYNMGT-ERNCFTVTAYRR 1284

  Fly  1309 HAVANLKPSWVRLYDYYATERSATEFYHVD-TSLCDICHGNECGNMC 1354
            ..||..:|::|.:||||.|.::|.:.|.|| .::|:||...:|...|
Mosquito  1285 FKVALKRPAYVVVYDYYDTNQNAIKVYEVDKQNVCEICDVCDCTTEC 1331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep1	NP_523578.1	YfaS	<117..1200	CDD:441940	289/1129 (26%)
		A2M_2	859..1135	CDD:239227	75/279 (27%)
		A2M_recep	1243..1336	CDD:462226	30/92 (33%)
LOC1278851	XP_318490.3	None