Protein Alignment Tep1 and LOC108647609

DIOPT Version :9

• Sequence 1: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_031758762.1
• Gene: LOC108647609 / 108647609
• -ID: -
• Length: 1389
• Species: Xenopus tropicalis
• Alignment Length: 1481
• Identity: 382/1481 - (25%)
• Similarity: 658/1481 - (44%)
• Gaps: 266/1481 - (17%)

  Fly     5 ILSSTILHCVLL-------SNANGLYSVLAPKTLRSNSAYNVVVAIH---NTTRTTEVSVSLTGP 59
            :|...:|.|:.|       |:|...|.:.||..:  :|..|..:::|   ::.....|:..:...
 Frog     3 LLDHLLLRCICLSLLIFHFSDARASYYISAPNIV--SSGINTTLSVHWFGSSYSEINVTAGILHQ 65

  Fly    60 SLNSRKYVDVQSMSSKSVRFDIP--KLTEGDYELKVMGSGGIE--FQNSTKLSFAPDLNWLYIQS 120
            .:...:...|....|..: ..||  .|...:|.|.|.||.|.|  |.|:..|:........:|::
 Frog    66 DVTVVQATQVFQKDSIGI-MSIPATPLDSSNYFLFVNGSAGNELIFSNNFGLTIKQIQTKTFIET 129

  Fly   121 DKATYKPGDKIQFRVLFLDKNTRPAVIDKPIKIEIRDGDQNLIKSWKDIKPAKGVYSGELQLSDR 185
            ||..|:|.:.::.|::.:..:..|  ...||.|.|||...::||...:.....||:|.|:.|..:
 Frog   130 DKKNYRPQETVKIRIITVYTDLTP--YKGPINIYIRDSSYDIIKQILNQNTELGVFSTEVLLPAK 192

  Fly   186 PVLGNWTVTATVQDEGKVTNVLVVDKYVVPKFEVVVLTAKNVAASAGYIRA------TIKARYTF 244
            ..||:.:::|.........:::||.. ..|.|:|.:     ||.|..|.::      .:.|.|:.
 Frog   193 SALGSLSISAGPNGYESYESIVVVQN-EPPDFDVTI-----VAPSYYYKQSKQDFVGKVFANYSN 251

  Fly   245 KKPVKGHVVATIEGSSTE----QSLPID-----------GEVNVEFPISATAK-----RLLKITA 289
            .:||||.|..::...:..    .|.|.|           |.||..|..|...|     ||: :||
 Frog   252 GRPVKGTVTLSLNFDTYNIYYYDSYPEDLTDVNKIFEIYGSVNFSFSYSEAFKCPFWQRLI-LTA 315

  Fly   290 IVTEELTDIKHNGTAYV--TVHQHR----HKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPVMDSS 348
            .||||.|......:.|:  ...|:|    .:|:..|      |..:...|..::..|..|:  :.
 Frog   316 SVTEEKTGKTVTASWYIQRATSQYRIFVVGQLDYSF------PNQAITAKIQIQRSDDLPL--TQ 372

  Fly   349 KMVNFNVLC-----CQVSKNFSASLQNSIATEHIMLPETCQSCLVTSTFDTAENIERYI---YKL 405
            :.:|.|||.     ..:::.:|.|....:   :|.:|      ....:|.::.:...|:   ||.
 Frog   373 EEMNTNVLITFGNYLPITRTYSISASGIL---NIQIP------FYDYSFHSSHSYVLYMTATYKD 428

  Fly   406 N--------------KPLMIAINTKKPQ------LRKLLKINIISDTYLPYFILTVVARGNIVLS 450
            :              .|   |:|.|.|.      :...:.:..:.:....|:   ||:.|.::::
 Frog   429 STHQWTVFTPDTWYWNP---AVNIKGPDTPVQTGIPFTISVGTVPEVQYVYY---VVSGGGVIVA 487

  Fly   451 LFQEMKEKKKSQEIEFEPTFALVPQATIFVHYIIDGVLMSDEKTVDIERDFENTIEILTTN---- 511
               ..|....|..:..|.::  :|...:..::|      :.::....:..|...|..:|.|
 Frog   488 ---AGKTSNSSFTLTAETSW--LPSVQVTAYFI------NPDERFGSDIGFNTKIFHITGNKVAL 541

  Fly   512 -----EALPRDEVSLKVK--TNPHSFVGLLGVDQSVLLLRSGNDLNRDLILNNLATYSTDLVILT 569
                 :|.|.:.|||.:.  |...:.|||...|.:..|  |||       .|:||
 Frog   542 SWSKSKAKPSEYVSLTISNITKTPAIVGLKVADINDKL--SGN-------TNSLA---------- 587

  Fly   570 NANI-NIYRSSGGCYTNPGYTNCTGSL-----IGRTMFKNEPTKNSGPV--PIVGSTRAQASLPP 626
             |.: |||  ||..|:  .|::  |::     .|..:..|:|  |:.|:  |:           .
 Frog   588 -AKVENIY--SGNSYS--PYSD--GNIGDPYSYGLQLHSNDP--NNDPINQPV-----------N 632

  Fly   627 VRKLFPETWLFSNITDVGANGEYIIKETVPDTLTSWVITGFSLSPQSGLAVTRNPSRIRVFQPFF 691
            :|.|.||||::.. |.:.:.....::.|:|..:.:||.:.|.:|...||.|:.....:.||||..
 Frog   633 LRPLIPETWIWLE-THISSGVNSSLQVTLPHKVMTWVASAFVISEGLGLGVSEQYPELEVFQPLL 696

  Fly   692 ITTNLPYSVKRGEVIAIPVIVFNYLGMDVKAKVLMDNSDGQYEFIETTNKNVSQYLRGVRRKKTL 756
            :|.|.|.:|.|||...:.|.:..|:..|.:..|:::.|......|...|.|      .|..::::
 Frog   697 LTLNAPRTVIRGENFILKVTLEAYIATDFQVTVMLEPSSSFEIIIPDNNTN------SVPGQRSV 755

  Fly   757 WIPANTGRGISFMIRPKKVGLTTLKITAISKYAGDRLHQILKVEADGVQKYVNKAVLINVQRLNR 821
            :|.:|..:.:.|.|.|||:|..:|.:.|.:....|...|.:.|:|:|:|.:.:.:|::|.....:
 Frog   756 FIQSNGSKEVLFPINPKKLGEMSLTVQANALGFSDSATQTVLVKAEGIQHFYSSSVILNGTDGKK 820

  Fly   822 RSLAPPEKTIIIEKADNVIEGSETVEFEVCGTSQAPQLEHLDDLVHLPCGCGEQNMFNFVPSILA 886
            .|...|.         :|:..::.....:.|...||.::.|:.|:.||.|||||||.:|.|.|..
 Frog   821 LSFTFPV---------DVVVDTKQASLSITGNFLAPSIKGLESLIQLPTGCGEQNMIHFAPVIYI 876

  Fly   887 LSYLKAKNRQDQEIENKAKRYVETGYQIELNYKRNDGSFSAWGQHDALGSTWLTAYVIRSFHQAA 951
            |.||.|..:..::...||.|::|.|||.||||:...|||||:|..|...||||:|:|:|...||.
 Frog   877 LQYLIASKQITEDFRTKAIRFMEKGYQTELNYQTYYGSFSAFGSTDFPASTWLSAFVLRCLLQAR 941

  Fly   952 KYIDIDKNVLVAGLDFLVSRQSTD-GKFKEL-------------GMVIHNSHGSPLALTSFVLLT 1002
            ::|.|.::||.....:|....:.: |.|:|.             |::.||         :::|:.
 Frog   942 QFISISEDVLSRTKKWLFFNLNEETGIFQESEQILKTRLQVGSNGVIAHN---------AYILIA 997

  Fly  1003 FFENEEYMPKYKHV---IDRAVEFVVTEVHQ---SNEPYDLAIAALALSLARNRNAYKVLDKLDK 1061
            ..|:|    ..|:|   :::.::::..:..:   ||  |.|:|.|.|||:|.:..|...|.:|:.
 Frog   998 LLEDE----SNKNVAYRMNKTIQYLENKTEEGITSN--YTLSIVAYALSVANSSKAAAALTQLNS 1056

  Fly  1062 LATRRGDHKWW-TGSDKCK-----SSEVETTSYVLLALLEHNISDEPKPIVDWLISKRNSNGGFV 1120
            .|...|..::| :|.|...     |:::||.:|.||:..:.|...|..||::||...||..||:.
 Frog  1057 RANSTGLQRYWSSGIDPSNDWQPLSADIETAAYALLSHCQQNRIAEGVPIMNWLSQHRNHLGGYS 1121

  Fly  1121 SSQDTVVGIMALTKY-ELQSHASTEAIDIEFWHLNEDKKHV-----RVTKENEFKVQTHQL-PEN 1178
            |:|||::.:.||||: .|...::..::.:..    .|...:     .:|.||...||:.|: ...
 Frog  1122 STQDTIMALQALTKFMTLVPTSNNTSLTVSV----TDSGSIVPNTFNITNENLLVVQSQQIYALE 1182

  Fly  1179 TNEVKLLAKGQGRAQVQLTYRYNVATKEARPS--FKLTTTVKKSHK-GRLILGICGTYTPIAASE 1240
            ..|:.:.|.|:|.|.:||...|| :..||.||  |||:.||..|.. .|:.:.:|.:|     ..
 Frog  1183 PLELVVSAAGEGAALLQLNVVYN-SKGEAVPSEVFKLSATVDDSDSHNRISVNVCSSY-----QG 1241

  Fly  1241 RNKTTNMALMQVQLPSGYVCDIEPFADIEAISDVKRVETKNEDTEVHIYFEKLSPGDRKCLTLEA 1305
            ..|...|.|.:|.:.||:  .::| ..|.....:|.||||:|  :|.:||:.:: ....|:.:..
 Frog  1242 PEKEPGMILWEVDMLSGF--KLDP-VGINLNDPLKLVETKDE--KVFLYFDSMN-AIENCVAVPM 1300

  Fly  1306 IYTHAVANLKPSWVRLYDYYATERSATEFYHVD----TSLCDICHGNECGN 1352
            :.|..|...:|:.:.:.|||..|...|..|:.|    .::|:.| |..|.|
 Frog  1301 VRTSMVVGSQPALITILDYYNPEIRTTRIYNSDKLSKATVCEFC-GLNCNN 1350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep1	NP_523578.1	A2M_N	116..201	CDD:280081	23/84 (27%)
		A2M_N_2	411..542	CDD:285005	27/147 (18%)
		A2M	634..726	CDD:278630	27/91 (30%)
		A2M_2	859..1135	CDD:239227	102/301 (34%)
		A2M_comp	910..1135	CDD:284982	80/250 (32%)
		A2M_recep	1245..1335	CDD:284981	25/89 (28%)
LOC108647609	XP_031758762.1	YfaS	54..1112	CDD:225248	295/1171 (25%)
		ISOPREN_C2_like	848..1136	CDD:415487	102/302 (34%)
		A2M_recep	1247..1330	CDD:400149	25/88 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010