Protein Alignment Tep1 and LOC108644844

DIOPT Version :10

• Sequence 1: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_031761243.1
• Gene: LOC108644844 / 108644844
• XenbaseID: XB-GENE-29090311
• Length: 1468
• Species: Xenopus tropicalis
• Alignment Length: 1556
• Identity: 378/1556 - (24%)
• Similarity: 632/1556 - (40%)
• Gaps: 310/1556 - (19%)

  Fly     1 MLWLILSSTILHCVLLSNANGLYSVLAPKTLRSNSAYNVVV----AIHNTTRTTEVSVSLTGPSL 61
            |..|:|..:::..|....|...|.:|||..:...|.....|    |..|.|.||.:.......:|
 Frog     1 MFLLLLFCSLIWKVFAQAAAPYYILLAPAEVHYPSTERACVHVSGARENLTLTTTLQTEGRDTTL 65

  Fly    62 NSRKYVDVQSMSSKSVRFDIPKLTEGDYE-----LKVMGSGGIEFQNSTKLSFAPDLNWLYIQSD 121
            ......:...:...|  |..|....|..|     :.:||. ..|...|.::..........||:.
 Frog    66 YQHHLTEATQIQCFS--FQTPPPAGGTEEVATIHISLMGK-TTEITESKQILIRSVAVSTIIQTS 127

  Fly   122 KATYKPGDKIQFRVLFLDKNTRPAVIDKPIKIEIRDGDQNLIKSWKDIKPAKGVYSGELQLSDRP 186
            :..||||..::|.:|..|:..| ||.||...:|::|.:.|.|..|.::.|.:|..  :|..|..|
 Frog   128 QPIYKPGQTVKFGILSFDREFR-AVNDKCPFVELKDPNGNQIGQWSNLTPHQGFI--DLSFSLAP 189

  Fly   187 VLGNWTVTATVQDEGKVTNVLVVDKYVVPKFEVVVLTAKNVAASAGYIRATIKARYTFKKPVKGH 251
            .....|.:....:..:..:||   ::.:|||||.||....|.......:..:..|:||.|||:|:
 Frog   190 EAAQGTYSIHTPNGHQKFHVL---EFTIPKFEVFVLLPSVVTLLDKAFQLKVCGRHTFGKPVQGN 251

  Fly   252 V---------------------VATIEGSSTEQSLPIDGEVNVE-FPI-SATAKRLLKITAIVTE 293
            :                     :.|:....||::.....|:..: |.: |...:...:.:|.:..
 Frog   252 ISVRLCRRVVKYYWGPYPRPQDICTVYNGQTEKNGCRTWEILTDSFQLRSYNYQANFEASAFLVG 316

  Fly   294 ELTDIKHNGT---------AYVTVHQHRHKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPVMDSSK 349
            ..|.::.|||         |.||:....      ...::|:.|:.......:...||.|:
 Frog   317 RETGVQINGTGSCRISAMIAKVTIDGSE------ISESYYKTGLRYRGTMRLEGADGKPM----- 370

  Fly   350 MVNFNVLCCQVSKNFSASLQNSIATEHIMLP-ETCQSCLVTSTFDT---------------AENI 398
                        |:.:..|.....:|....| ||.:|.....|.||               .||:
 Frog   371 ------------KSKTLYLVEEYDSESRERPYETDESGQAPFTLDTRLWNGNTVWLSARYQKENM 423

  Fly   399 ERYIY-KLNKPLMIAINTKKP---QLRKLLKINIISDTYL---------PYFI------------ 438
            | ::| :||.....|..|.:|   .....||:..:..|.|         .|.|
 Frog   424 E-FVYGELNPYYQDAHQTLQPFSAITNSFLKVQPVDHTLLCDQQYPIEIDYLIRGSELGREQNSL 487

  Fly   439 ---LTVVARGNIVLSLFQEMKEKKKSQ-----EIEFEPTFALVPQATIFVHYII-DGVLMSDEKT 494
               ..|:|:|.:.|:...|:...:.|.     |:....|..:.|:|.|.|:.|: :|.:..|.:.
 Frog   488 ELHYVVMAKGELALNGKLELNVSRDSVLTGTIELPLLVTADIAPKAQILVYAILANGWVAGDTEE 552

  Fly   495 VDIERDFENTIEI-LTTNEALPRDEVSLKVKTNPHSFVGLLGVDQSVLLLRSGNDLNRDLI---- 554
            ..:::.|:|.:.. .:..|..|...|||.::.:|.|...|..||:.::.||...:|:.||:
 Frog   553 FRVDKCFKNKVTAGFSDYEKTPGSNVSLHLQASPGSLCSLRVVDEGIISLRPEAELSSDLLYSFV 617

  Fly   555 ----------------------------------------LNNLATYSTD---------LVILTN 570
                                                    :|.....|.|         |.||||
 Frog   618 SVRNQYGYPYRVREDDPICWSPSPRFSKRSLNGHERQKRHINWRTPRSLDMFKLIKRMGLKILTN 682

  Fly   571 ANINIYRSSGGCYTNPGYTNCTGSLIGRTMFKNEPTKNSGP------VPIVGSTRAQAS--LPPV 627
               .|.:....|:..|.....:...:...:|...|   |.|      |.|:|.:....:  ...:
 Frog   683 ---TIVKKPKECHVYPPVAALSRYDLSVDLFNPPP---SPPVMVDDLVDILGQSSPTLTEVKEKI 741

  Fly   628 RKLFPETWLFSNITDVGANGEYIIKETVPDTLTSWVI-------TGFSLSPQSGLAVTRNPSRIR 685
            ||.|||||:: :...:|.:|:..::..||||:|.|..       ||..|||.:.|         |
 Frog   742 RKDFPETWIW-HFIPLGNSGQASMELKVPDTITEWKAKMLCMGDTGLGLSPTATL---------R 796

  Fly   686 VFQPFFITTNLPYSVKRGEVIAIPVIVFNYLGMDVKAKVLMDNSDGQYEFIETTNKNVSQYLRGV 750
            .||||||...|||||.|||...:...|||::...:.....:..|..    ::.|......|.:.|
 Frog   797 AFQPFFIYMTLPYSVVRGESFPVKASVFNFMNRTLMVTSTLKESPK----LKLTGCPACLYTQCV 857

  Fly   751 RRKKT---LWIPANTGRGISFMIRPKKVGLTTLKI------TAISKYAGDRLHQILKVEADG--V 804
            ...:|   :|.....|.| |..:..:...:.|.::      |.....|.|.|.:.|:::.:|  |
 Frog   858 APGETKVFVWEATALGLG-SAQVEVRAEAIPTGELCGGEVPTVPEDGALDILIRPLEIKPEGMPV 921

  Fly   805 QKYVNKAVLINVQRLNRRSLA---PPEKTIIIEKADNVIEGSETVEFEVCGTSQAPQLEHLDDLV 866
            :|..| .:|...:.|:.::::   ||:          ::..|...|..:.|......||::::|:
 Frog   922 EKCQN-FLLCAEENLSSQAVSISLPPD----------MVPDSARAEISIVGDLMGKPLENVENLL 975

  Fly   867 HLPCGCGEQNMFNFVPSILALSYLKAKNRQDQEIENKAKRYVETGYQIELNYKRNDGSFSAWGQH 931
            .||.|||||||..|..::..|.||:..|:....:..:.:.|...|||.||||||.||||||:|:.
 Frog   976 DLPTGCGEQNMAKFASNLYVLRYLENTNQLTDTVRVRGEVYQAHGYQQELNYKRLDGSFSAFGEK 1040

  Fly   932 DALGSTWLTAYVIRSFHQAAKYIDIDKNVLVAGLDFLVSRQSTDGKFKELGMVIHNS----HGSP 992
            |..|:|||||:|::.|:..:.:|.:|:..|...:.:|.|.|...|.|...|.:..:|    ....
 Frog  1041 DEEGNTWLTAFVMQIFYAVSHFISVDEKHLYEAIAWLKSNQLPSGCFIRRGTLFKSSLQGGVNDE 1105

  Fly   993 LALTSFVLLTFFE---NEEYMPKYKHVIDRAVEFVVTEVHQSNEPYDLAIAALALSLARN---RN 1051
            ..||::|.....:   .||     ..::.:|::.:...:......|.:|:.:...:||:|   ||
 Frog  1106 TTLTAYVAAAILQIKWTEE-----DEMLQKALQCLQNSLPNVTSTYAMALLSFTFTLAKNFELRN 1165

  Fly  1052 AYKVLDKLDKLATRRGDHKWW----TGSDKCKSS--------EVETTSYVLLALL------EHNI 1098
            :  :|..|.:.||...|..:|    ..:...|:|        :||..|||:|:.|      :::|
 Frog  1166 S--LLRSLYEKATITDDQVYWLLNPNQAPPTKTSPWAQPNSLQVEAASYVILSHLSLENPTKNDI 1228

  Fly  1099 SDEPKPIVDWLISKRNSNGGFVSSQDTVVGIMALTKYELQSHASTEAIDI------------EFW 1151
            .:..| |..||..::|.:|.|.|:|||||...||::|...|:.....:::            :||
 Frog  1229 CNASK-IASWLRQQQNPHGSFGSTQDTVVAFHALSRYAEISYTGHLGLEVTVELAEEGGAKHQFW 1292

  Fly  1152 HLNEDKKHVRVTKENEFKVQTHQLPENTNEVKLLAKGQGRAQVQLTYRYNVATKEARPSFKL-TT 1215
                      |..:..|.:|..:|.:.........||:|...:|:..:||.......|:|:| ..
 Frog  1293 ----------VDNKTRFLLQKTRLDKVPGNYTTRVKGEGCVNLQVILKYNTKPAGKSPAFELRLR 1347

  Fly  1216 TVKKSHKGRLI----LGICGTYTPIAASERNKTTNMALMQVQLPSGYVCDIEPFADIEAISDVKR 1276
            :.:.|.:.:.:    |.||..||    .:|.| |||.|:|..|.||:....|...::|....||:
 Frog  1348 SSEDSCRNQSVSCYNLTICVQYT----GQRQK-TNMVLIQADLLSGFSSIPETINELENHHLVKK 1407

  Fly  1277 VETKNEDTEVHIYFEKLSPGDRKCLTLEAIYTHAVANLKPSWVRLYDYYATERSATEFYHV 1337
            :|.|.:  ::.||.::|| .:.:|.:..|.....|.||....|::||:|..|......|::
 Frog  1408 IEIKMD--QIVIYIDELS-HETQCFSFLARQDVLVENLASQLVKVYDFYQREEEVDAMYNL 1465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep1	NP_523578.1	YfaS	<117..1200	CDD:441940	310/1287 (24%)
		A2M_2	859..1135	CDD:239227	97/303 (32%)
		A2M_recep	1243..1336	CDD:462226	29/92 (32%)
LOC108644844	XP_031761243.1	YfaS	<129..1331	CDD:441940	308/1281 (24%)
		A2M_2	968..1264	CDD:239227	97/303 (32%)
		A2M_recep	1374..1464	CDD:462226	29/93 (31%)