Protein Alignment Tep1 and LOC100491968

DIOPT Version :9

• Sequence 1: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_031755349.1
• Gene: LOC100491968 / 100491968
• -ID: -
• Length: 1653
• Species: Xenopus tropicalis
• Alignment Length: 1574
• Identity: 378/1574 - (24%)
• Similarity: 652/1574 - (41%)
• Gaps: 307/1574 - (19%)

  Fly     1 MLWLILSSTILHCVLLSNANGLYSVLAPKTL-----RSNSAYNVVVAIHNTTRTTEVSVSLTGPS 60
            :|.|:..|....|.|::.:  |..|...:|:     ..|||::..:.|.:..: .::|::....|
 Frog    10 LLLLVAGSYAQQCTLITPS--LLRVETEETIVVDAQGHNSAFDANILIQDFPQ-KKLSLASAKVS 71

  Fly    61 LNSRKYVDVQSMSSKSVRF---DIPKLTEGDYELKV-MGSGGIEFQNSTKLSFAPDLNWLYIQSD 121
            ||:..    ..:.|.:|:.   .:||.|..:..:.| :.||....:....|.::.  .:::||:|
 Frog    72 LNNSN----GFLGSGTVKIPSDQLPKETRNNQFVYVSVSSGSCTLEKVVLLQYSS--GYIFIQTD 130

  Fly   122 KATYKPGDKIQFRVLFLDKNTRPAVIDKPIKIEIRDGDQNLIKSWKDIKPA--KGVYSGELQLSD 184
            |..|.||.|:.:||..::....|  :.||:.||..:.| .::...:.|.||  .|:.|....|.:
 Frog   131 KTIYTPGSKVMYRVFSMNYKMYP--VAKPMVIEFVNPD-GIVVMRESIHPASKSGILSETHDLPE 192

  Fly   185 RPVLGNWTVTATVQD--EGKVTNVLVVDKYVVPKFEVVVLTAKN-VAASAGYIRATIKARYTFKK 246
            ...||.||::|..:|  :...|....|.:||:|..|:::....: ....|......|:|.|.|.:
 Frog   193 LVSLGVWTISAKYEDTPQQNYTTNFEVKEYVLPTIEIILKPESSFFYTDAKTFSVNIEAHYLFGR 257

  Fly   247 PVKGHV------------------VATIEGSSTEQSLPIDGEVNVEFPISATAKRL---LKIT-A 289
            ||:||.                  :|.::.:..|..:.::|| ::...::.|.:.|   |.:| :
 Frog   258 PVEGHAFVLFGVQKDGRKTGIPESLARVQINEGEGRVELEGE-HIRKTLNTTEEMLQYKLYLTVS 321

  Fly   290 IVTEELTDIKHNGTAYVTVHQHRHKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPV---------- 344
            :||...||:.......:.:....:|:.....|.:::||:|.:....|.|.||||.
 Frog   322 VVTATGTDMVEAQLEEIYIVTSPYKVFFTKTPQYFKPGLSFDVMVFVTNPDGSPAKGIPVVVQPG 386

  Fly   345 -------MDSSKMVNFNVLCCQVSKNFSASLQNSIATEHIMLPETCQ-SCLVTSTFDTAENIERY 401
                   .|.:..:..|      :...:..|..::.||...||...| :..:|:|        .|
 Frog   387 GISGVTQTDGTTRLPMN------TPPDTNELHVTVRTEQEGLPPQHQANATMTAT--------AY 437

  Fly   402 IYKLNKPLMIAINTKKPQLRKLLKINII---SD----TYLPYFILTVVARGNIVLSLFQEMKEKK 459
            ..:....|.|.|...:..|.|.|.:|..   ||    ..:.:|...|::||.|:        :..
 Frog   438 GSETGNYLHINIAESEITLGKGLSVNFFIKNSDPRFQEQIQHFTYLVLSRGQII--------KVD 494

  Fly   460 KSQEIEFEPTFAL--------VPQATIFVHYIIDGV----LMSDEKTVDIERDFENTIEIL---- 508
            :...:..:|..|:        :|...|..:|::...    ::||...||:......|:|:.
 Frog   495 RQARLSDQPVVAMSLLITEDYLPSFRIVAYYMVTTAKGRDIVSDSVWVDVVDSCMGTLEVTGLKD 559

  Fly   509 --TTNEALPRDEVSLKVKTNPHSFVGLLGVDQSVLLLRSGNDLNRDLILNNL------------- 558
              ...:.||. .|.||::.:..:.|||:.||:.|.:|.....|.:..|.:::
 Frog   560 KDNAVQKLPA-TVQLKLRADHKANVGLVIVDKGVFVLNKKFKLTQSKIWDSVEKSDIGCTPGSGV 623

  Fly   559 ----------ATYSTDLVILTNANINIY---------RSSGG------------------CYTNP 586
                      .|..|...|.|...|..|         ||:..                  |..:.
 Frog   624 DSPGVFYDAGLTLHTSFAITTIQRIKPYCKVPGKRKRRSTAAIIEIKAGKASEYKDKVKQCCLDG 688

  Fly   587 GYTNCTG-SLIGRTMF--------------------KNEPTKNSGPVPIVGSTRAQA-----SLP 625
            ...|..| |...||.:                    :.|..:.|.....:..:...:     |..
 Frog   689 MQENLMGHSCERRTRYILDGKECVDAFLDCCKYYEKRREDERKSKDEDTLARSDEDSDYILESEI 753

  Fly   626 PVRKLFPETWLFSNITDVGANGE------YIIKETVPDTLTSWVITGFSLSPQSGLAVTRNPSRI 684
            .||..|||:|.: ::.::..|.:      .||...:.|::|:|.:...|||...||.|. .|..|
 Frog   754 DVRSEFPESWRW-DVVEMRENPDKQNISTKIINLNLKDSITTWEVLAVSLSENKGLCVA-PPHEI 816

  Fly   685 RVFQPFFITTNLPYSVKRGEVIAIPVIVFNYLGMDVKAKVLMDNSDGQYEF--IETTNKNVSQYL 747
            :..:.|||...|||||.|.|.:.|..:|.||....:||:|....:.   ||  :.|..|...|
 Frog   817 KAMKDFFIDLKLPYSVVRNEQVEIRAVVHNYNSNRIKARVEFSYNP---EFCSLSTAKKKFRQ-- 876

  Fly   748 RGVRRKKTLWIPANTGRGISFMIRPKKVGL--TTLKITAISKYAGDRLHQILKVEADGV--QKYV 808
                   .:|:.|.:...:.|:|.|..:|.  ..:|.:....:..|.:.:.|||..:||  .|.:
 Frog   877 -------EVWVGAESSAVVPFVIVPLTIGQHDVEVKASVYKHFFSDGVRKTLKVVPEGVLLTKTL 934

  Fly   809 NKAVL-------INVQRLNRRSLAPPEKTIIIEKAD----NVIEG---SETVEFEVCGTSQAPQL 859
            :...|       ..||.:|..:|....   |:.::|    .:::|   |:.||..:.|.:..|
 Frog   935 SSVTLEPEVKGKDGVQEVNIGALTAEH---IVPRSDVDIKVILQGSPISQLVESAIDGINLHP-- 994

  Fly   860 EHLDDLVHLPCGCGEQNMFNFVPSILALSYLKA--------KNRQDQEIENKAKRYVETGYQIEL 916
                 |:.:|.|||||||.....:::...||.|        .:|:...|.|.||     |||.||
 Frog   995 -----LIQIPTGCGEQNMMRMTTNVITTRYLDATAQWQRVGMDRRVAAIRNIAK-----GYQEEL 1049

  Fly   917 NYKRNDGSFSAWGQHDALGSTWLTAYVIRSFHQAAKYIDIDKNVLVAGLDFLVSRQSTDGKFKEL 981
            .|::.||:|:|:  .|...||||||||.:.|..:.:|..|:.|||...:.:| .::..:|.|.|.
 Frog  1050 VYRKPDGTFAAF--KDRPSSTWLTAYVAKVFAMSYEYTQIEDNVLCGAIKWL-EKKMQNGMFIES 1111

  Fly   982 GMVIH------NSHGS---PLALTSFVLLTFFENEE----YMPKYKHVIDRAVEFVVTEVHQSNE 1033
            |.|||      |..|:   ..|||:|||:...|:.|    .:......|:||.:|:..:..|..:
 Frog  1112 GPVIHMEMVGGNKAGAAEPDAALTAFVLIAMLESRELCTQQLTSLGDSINRATDFLRGKYSQLRK 1176

  Fly  1034 PYDLAIAALALSLARNRNAYKVLDKLDKLATRRGDHKWWTGSDKCKSSEVETTSYVLLALLEHNI 1098
            ||.:||.:.||:||..      |...:.|.....|...|...|....| :|.|||.||.||:...
 Frog  1177 PYSIAITSYALALAGE------LQDTNTLMNAATDKTHWNEPDSLFIS-LEATSYALLTLLKMKQ 1234

  Fly  1099 SDEPKPIVDWLISKRNSNGGFVSSQDTVVGIMALTKYELQSHASTEAIDIE---FWHLNEDKKHV 1160
            .|....||.||..||.....|.|:|.|::...||.:|::.. ...:.:|::   :....:|..:|
 Frog  1235 HDPTGAIVRWLNEKRYYGAVFNSTQATIIMFQALAQYQIDV-PRIDDLDLDVSLYLPEKQDPINV 1298

  Fly  1161 RVTKENEFKVQTHQLPENTNEVKLLAKGQGRAQVQLTYRYNVATKEAR---PSFKLTTTVKKSHK 1222
            |:..||....::.:...|.:.| :.|||:|:|.:.:...::....|.:   .:|.|:..|::...
 Frog  1299 RIDLENAILARSTETKINKDFV-VKAKGKGQALLTVVSVFHSLETEKQMECNNFNLSVKVEEEKN 1362

  Fly  1223 GRLILG--------ICGTYTPIAASERNKTTNMALMQVQLPSGYVCDIEPFADIEAISD--VKRV 1277
            .:|..|        :|..|.      ::....|::|.:.:.:|:..|.:....:...:|  :.:.
 Frog  1363 MKLPDGVVAIVSVEVCARYL------KDSDATMSIMDISMMTGFSPDTDSVNKLMKGADKYISKY 1421

  Fly  1278 ETKNEDTE---VHIYFEKLSPGDRKCLTLEAIYTHAVANLKPSWVRLYDYYATERSATEFYHVDT 1339
            |.....||   :.:|.:|:|..:.:|:...|.....|..::|:.|.:||||..|...|:|||.:.
 Frog  1422 EINKGATERGTIILYLDKISHTEPECVKFYAHQYFVVGLVQPASVTVYDYYTPENRCTKFYHTEE 1486

  Fly  1340 SLC---DICHGNEC 1350
            |..   .:|.|:.|
 Frog  1487 SSALFGKLCQGDVC 1500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep1	NP_523578.1	A2M_N	116..201	CDD:280081	28/88 (32%)
		A2M_N_2	411..542	CDD:285005	35/155 (23%)
		A2M	634..726	CDD:278630	32/97 (33%)
		A2M_2	859..1135	CDD:239227	100/296 (34%)
		A2M_comp	910..1135	CDD:284982	83/237 (35%)
		A2M_recep	1245..1335	CDD:284981	22/94 (23%)
LOC100491968	XP_031755349.1	MG1	19..118	CDD:407662	21/105 (20%)
		A2M_N	124..219	CDD:396416	29/97 (30%)
		YfaS	<125..>336	CDD:225248	55/214 (26%)
		MG4	347..437	CDD:407661	20/103 (19%)
		A2M_N_2	445..595	CDD:400170	36/158 (23%)
		ANATO	673..732	CDD:237984	7/58 (12%)
		A2M	762..857	CDD:395153	31/96 (32%)
		complement_C3_C4_C5	991..1271	CDD:239226	101/301 (34%)
		A2M_recep	1387..1482	CDD:400149	22/94 (23%)
		NTR_complement_C3	1502..1651	CDD:239638

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010