Protein Alignment CG7653 and APE2

DIOPT Version :9

• Sequence 1: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_012765.3
• Gene: APE2 / 853699
• SGDID: S000001640
• Length: 952
• Species: Saccharomyces cerevisiae
• Alignment Length: 696
• Identity: 171/696 - (24%)
• Similarity: 297/696 - (42%)
• Gaps: 100/696 - (14%)

  Fly    32 CSAKTQLYDE-PR---LPAKVKPFHYDIRLLTHLESSANHSYTGIVKISIHAQK-TTNQVVLHVG 91
            |...:||.:: |.   ||..|.|.|||   ||.........:.|.|||.:.... ..:.|.|:..
Yeast    86 CQKTSQLLNKTPNREILPDNVVPLHYD---LTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTV 147

  Fly    92 RVSIESKKITLFGETSNYRLRSVRFNNDRKYMVVTF-----NQSLLMGKSYVLSVEFGRPMTMDQ 151
            ...|.|.||   |:.::..:.|     :.:..|.||     ..|...|.:: |.::| ..:..|.
Yeast   148 DTDIHSAKI---GDVTSSEIIS-----EEEQQVTTFAFPKGTMSSFKGNAF-LDIKF-TGILNDN 202

  Fly   152 RDGYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMPSFDEPSLKATFNVTMGHHKRFQSYGNMKVQ 216
            ..|::...|.:..|.|..:.:.:.......|...|.||||:|||:|.:|:..........||.|:
Yeast   203 MAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVK 267

  Fly   217 AVLPNREIQD-YVWSVHEVTPTIPTHLLAFSVNNFNCRYSQAASLS-PVRFRTCAQSADVRATSF 279
                |..::| ...::...||.:.|:|:||.|...  :|.::.:.. ||  |..|...:.:...|
Yeast   268 ----NEYVKDGKKVTLFNTTPKMSTYLVAFIVAEL--KYVESKNFRIPV--RVYATPGNEKHGQF 324

  Fly   280 AAQMAPQILEFLDRVLQVALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQ 344
            ||.:..:.|.|.::...:..||.|:|.:.|.:|...||||:|||.||...|||.:|........:
Yeast   325 AADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQR 389

  Fly   345 TLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLAGYFKSLAVDHLQSKMGRRILLRYRESSMMYES 409
            ..|::.||:||.||.||:.||.:..|||.||.|.:....:.:..|.:.  ::..:|...::.:..
Yeast   390 VAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEW--KVWEQYVTDTLQHAL 452

  Fly   410 QVGGISL-----VPLSSNASLNA--ETQLYQKATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSS 467
            .:..:..     ||:.....:|.  :...|.|..||..|:..:||.|||..|:.:::.:..:|::
Yeast   453 SLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNA 517

  Fly   468 TPDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPLVTVIRNGS-EVFLKQGHALNRS--- 528
            ..:..|.:|..||.:        ||:|:|:.||.:.|:|:::|..:|: ::..:|...|:.:
Yeast   518 KTEDLWDALADASGK--------DVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNRYLSTADVK 574

  Fly   529 ---SSHLWWIPLTYLIEGGSLSKNLKPKAWLSPNSHGIKLNDIVPRNQWILLNLQAVGYYRVNYD 590
               ...::.:.|....:.|     :.....||..|..|:|.|    ..:..:|.:..|.|..:|.
Yeast   575 PDEDKTIYPVFLALKTKNG-----VDSSVVLSERSKTIELED----PTFFKVNSEQSGIYITSYT 630

  Fly   591 ELTWQLLATTLFNDFRSINVLNRAQIVSDVLFL-----------------WNQD--LLAWSTALN 636
            :..|..|....  |..|:.  :|..:|:||..|                 ||.:  .:.|...:|
Yeast   631 DERWAKLGQQA--DLLSVE--DRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKSFVVWDQIIN 691

  Fly   637 VLKYIIDEDEYEP----------LMAFVVGWTNGF-WGISTESSFN 671
            .:..:.....:||          ....:.|.|:.. |...:..||:
Yeast   692 SISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFS 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	123/462 (27%)
		ERAP1_C	574..>652	CDD:338125	19/106 (18%)
		dnaA	630..>701	CDD:234667	9/53 (17%)
APE2	NP_012765.3	PepN	90..941	CDD:223385	170/692 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010