Protein Alignment CG7653 and erap1a

DIOPT Version :10

• Sequence 1: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_692516.3
• Gene: erap1a / 564068
• ZFINID: ZDB-GENE-091113-7
• Length: 933
• Species: Danio rerio
• Alignment Length: 701
• Identity: 193/701 - (27%)
• Similarity: 312/701 - (44%)
• Gaps: 97/701 - (13%)

  Fly    19 YGLLLLLCLCQVACSA------KTQL---YDEPRLPAKVKPFHYDIRLLTHLESSANHSYTGIVK 74
            :.|:.|.|.......|      ||.|   :|:.|||..|||.|||:.:..:|.|.   ::||.|:
Zfish    10 FTLVALFCALFAGNHAMTVNKNKTVLPFPWDKMRLPEIVKPQHYDLLIHPNLTSL---TFTGEVQ 71

  Fly    75 ISIHAQKTTNQVVLHVGRVSIESKKITLFGETSNYRLRSVRFNN-DRKYMVVTFNQSLLMGK-SY 137
            |.|..::.|..::||  ..:::..|..|.|...::..:.::.:. :....:..|::.....| |:
Zfish    72 IQIEVKQDTRAIILH--SKNLQVSKALLLGSRQHHHHQDLQISEFEANEQIALFSEGFTFEKGSH 134

  Fly   138 VLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMPSFDEPSLKATFNVTMG 202
            |:.:||...:: |...|::...|.. .:.|....:.:.|.....|...|.||||:.||.|.:.:.
Zfish   135 VVHLEFYANLS-DSFHGFYKGQYTT-NSGEVRMLASTQFEPTHARAAFPCFDEPAFKANFTIRVR 197

  Fly   203 HHKRFQSYGNM-KVQAVLPNREIQDYVW-SVHEVTPTIPTHLLAFSVNNFNCRYSQAASLSPVRF 265
            ...|..|..|| |::.|    |:.|.:. ...:....:.|:|:||.:.:|:....::.....:..
Zfish   198 RESRHISISNMPKLRTV----ELADGILEDQFDTMVKMSTYLVAFIICDFHSISKKSQHGVEISV 258

  Fly   266 RTCAQSADVRATSFAAQMAPQILEFLDRVLQVALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHL 330
            .|..:.  :....:|...|..:|:|.|....:..||.|.|...:.||.:.||||:||..||...|
Zfish   259 YTVPEK--ISQAEYALDTAVTMLDFYDEYFDIPYPLPKHDLAAIPDFQSGAMENWGLSTYRESGL 321

  Fly   331 LLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLAGYFKSLAVDHLQSKMGRR 395
            |...:...|.:||...::||||:||.||.||:.|..::||||.||.|.:.:.::|:....::
Zfish   322 LFDPEKSSSSDKLGITKVIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEYVSVNITHPEL--- 383

  Fly   396 ILLRYRESSMMYESQVGGISLVPLSSNASLNAETQ------------LYQKATSLTSMLIGFLGN 448
                 :.:....|.....:|:..|||:..::...:            .|:|...:.:||..||..
Zfish   384 -----QVNDYFLEKCFTALSVDSLSSSHPVSTPVENPAEISEMFDDVSYRKGACILNMLRDFLTP 443

  Fly   449 ETFYDG----LQRHMWQNSFGSSTPDLFWRSLQ-----------------LASEREA-TFDKTW- 490
            |.|..|    |::|.:||:..|.    .|.||.                 ..|:..| |....|
Zfish   444 EVFKYGIINYLKKHSYQNTVNSH----LWESLTNICTSDGLDSGRLKLDGFCSKHTAETPASKWF 504

  Fly   491 -----DVKSIMDTWTMQSGYPLVTVIRNGSEVFLKQ-----GHALNRSSSHLWWIPLTYLIEGGS 545
                 ||.:||||||:|.|:||:||...|.||.|||     |...:.|||.||.:||||:..|
Zfish   505 KEDSVDVGAIMDTWTLQEGFPLITVEVKGQEVTLKQERFLKGAESSNSSSFLWQVPLTYITSG-- 567

  Fly   546 LSKNLKPKAWLSPNSHGIKLNDIVPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFNDFRSINV 610
              .|...:..|........|.:.|   :||..|:...|||.|:|:...|..|...|..:....:.
Zfish   568 --SNAVQRFLLKTERDVFYLPEKV---EWIKFNVDLRGYYIVHYESGGWDCLIKQLRMNHTVFSS 627

  Fly   611 LNRAQIVSDVLFLWNQDLLAWSTALNVLKYIIDEDEYEPLMAFVVGWTNGF 661
            .:||.::.|:..|.:.:.:....|||:..|:..|.|..|:       |.||
Zfish   628 NDRASLIHDIFQLVSIEKVPLDKALNLSLYLSKESEIMPV-------TQGF 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	125/491 (25%)
		ERAP1_C	574..>652	CDD:463368	22/77 (29%)
		dnaA	630..>701	CDD:455861	10/32 (31%)
erap1a	XP_692516.3	M1_APN-Q_like	52..520	CDD:341064	126/492 (26%)
		ERAP1_C	591..911	CDD:463368	25/88 (28%)