DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7653 and CG31198

DIOPT Version :9

Sequence 1:	NP_001356886.1	Gene:	CG7653 / 34935	FlyBaseID:	FBgn0028935	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_732654.1	Gene:	CG31198 / 318622	FlyBaseID:	FBgn0051198	Length:	940	Species:	Drosophila melanogaster

Alignment Length:	700	Identity:	190/700 - (27%)
Similarity:	317/700 - (45%)	Gaps:	96/700 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLLLLCLCQVACSAKTQL-------------YDEPRLPAKVKPFHYDIRLLTH-LESSANHSYT- 70
            :||:.|: .:|.:...||             .:|.||...:.|.:|:|.|..: ||:..|..:|
  Fly     8 VLLVACV-SLASAGTRQLSVDVQPPATLATELNEYRLAEHITPVNYNITLRPYLLETDGNKRFTF 71

  Fly    71 -GIVKISIHAQKTTNQVVLHVGRVSIESKKITL---------FGETSNYRLRSVRFNNDRKY--- 122
             |.|.|.:.:.:|||.:.||       ||.:|.         ..|.:|..:..:...|...|
  Fly    72 DGEVWIEVISNQTTNDIYLH-------SKNLTYSVREYWQKPTTEVANPTVIQISATNTTNYDTD 129

  Fly   123 -MVVTFNQSLLMGKSYVLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMP 186
             :.:|.:.:|....:|:|...:...|. |...|::...|::.....| |...:.|..:..|...|
  Fly   130 IVKLTASTALTANTTYILHFVYTGLME-DDMHGFYRSSYVDDNNVTK-WLGSTQFQTHHARRAFP 192

  Fly   187 SFDEPSLKATFNVTMGHHKRFQSYGNMKVQAVLPNREIQDYVWS-VHEVTPTIPTHLLAFSVNNF 250
            |||||..||||:||:..|:.|.|..|.::.:..|:.|  :.::| |::.||.:.|:||||.::.|
  Fly   193 SFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTE--EGIFSDVYKTTPKMSTYLLAFIISEF 255

  Fly   251 NCRYSQAASLSPVRFRTCAQSADVRATSFAAQMAPQILEFLDRVLQ---VALPLEKIDQLVVDDF 312
            ..|...       .|...|:......|.:...:..||||.:.:.|.   .::..:|:|...:.||
  Fly   256 VARKDD-------DFGVYARPEYYAQTQYPYNVGIQILEEMGQYLDKDYYSMGNDKMDMAAIPDF 313

  Fly   313 PTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLA 377
            ...||||:||:.||.:.||:.|.......:.....::|||.|||||.:|:....:|..||.||.|
  Fly   314 SAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFA 378

  Fly   378 GYF---------------KSLAVDHLQSKMGRRILLRYRESSMMYESQVGGISLVPLSSNASLNA 427
            .||               |...||.:||.|.       .:|:..........:..|...:...|:
  Fly   379 RYFQYFGTAMVEDKWELEKQFVVDQVQSVMA-------MDSTNATNPLSDENTYTPAHLSRMFNS 436

  Fly   428 ETQLYQKATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSSTPDLFWRSLQLASEREATFDKTWDV 492
            .:  |.|..:...|:...:|.:.|...||.::.:..:.||.|:....:.| |:...::::::  .
  Fly   437 IS--YNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLLGAWQ-ANWPNSSYNES--S 496

  Fly   493 KSIMDTWTMQSGYPLVTVIRNGSEV-FLKQGHALNRS----SSHLWWIPLTYLIEGGSLSKNLKP 552
            |.|..::|.|.||||:.|....|:| |.::...|..|    ||..:.:|::|.....:...|..|
  Fly   497 KDIFKSFTEQVGYPLINVTVGNSQVSFTQKRFLLKESDGSDSSLKYTVPISYTTSETNNFLNTTP 561

  Fly   553 KAWLSPN-SHGIKLNDIVPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFN-DFRSINVLNRAQ 615
            |..|.|| :..::.|..:   :||::|:|..|||||.|.:..|..:...|.. ::..|:..||||
  Fly   562 KFILKPNVTTTVQFNSTI---KWIVVNIQQTGYYRVTYSDDNWHAIHHALITANWGGIHENNRAQ 623

  Fly   616 IVSDVLFLWNQDLLAWSTALNVLKYIIDEDEYEPLMAFVVGWTNGFWGIS 665
            ||.|:..|.....:.::..|:|::|:..|..|.|       ||:.|.|.:
  Fly   624 IVDDLFNLARAGYVTYNLTLDVIEYLQTETNYIP-------WTSAFNGFN 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	126/482 (26%)
		ERAP1_C	574..>652	CDD:338125	27/78 (35%)
		dnaA	630..>701	CDD:234667	10/35 (29%)
CG31198	NP_732654.1	Peptidase_M1	42..442	CDD:279741	116/426 (27%)
		M1_APN_2	50..510	CDD:189008	129/489 (26%)
		ERAP1_C	582..898	CDD:288671	30/91 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020