Protein Alignment CG7653 and ape2

DIOPT Version :9

• Sequence 1: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_595998.1
• Gene: ape2 / 2540648
• PomBaseID: SPBC1921.05
• Length: 882
• Species: Schizosaccharomyces pombe
• Alignment Length: 691
• Identity: 179/691 - (25%)
• Similarity: 309/691 - (44%)
• Gaps: 99/691 - (14%)

  Fly    29 QVACSAKTQLYDEPR---LPAKVKPFHYDIRLLTHLESSANHSYTGIVKISIHAQKTTNQVVLHV 90
            ||.....|...|:..   ||..|||.|||:.|...||:   .:|.|.|.:::...:.:|.:.||
pombe     2 QVTIPKSTSKEDDKNRNLLPKNVKPIHYDLSLYPDLET---FTYGGKVVVTLDVLEDSNSITLH- 62

  Fly    91 GRVSIESKKITLFGETSNYRL--RSVRFNNDRKYMVVTFNQSLLMGKSYVLSVEFGRPMTMDQRD 153
               .|..:.:|...|..:..:  ..|.:.::|  :|:.|..::......||::.|...::... :
pombe    63 ---GINLRILTAALEWGSQTVWASEVSYGDER--IVLQFPSTVPANSVAVLTLPFTARISSGM-E 121

  Fly   154 GYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMPSFDEPSLKATFNVTMGHHKRFQSYGNMKVQAV 218
            |::...|::...:.| :.:.:.......|...|.:|||:|||||.:.:...:.:....||  .||
pombe   122 GFYRSSYVDSDGNTK-YLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNM--NAV 183

  Fly   219 LPNREIQDYVWSVH-EVTPTIPTHLLAFSVNNFNCRYSQAASLSPVRFRT----CAQSADVRATS 278
              ...::|.:.:.. ..|..:.|:|||:.|          |.|..|.:.|    |.: ..||..:
pombe   184 --EETVKDGLKTARFAETCRMSTYLLAWIV----------AELEYVEYFTPGKHCPR-LPVRVYT 235

  Fly   279 ---------FAAQMAPQILEFLDRVLQVALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLRE 334
                     |||::..:.|:|...|.....||.|.|.:.:.||...||||:|||.||...:|:.|
pombe   236 TPGFSEQGKFAAELGAKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVSE 300

  Fly   335 DGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLAGY---------------FKSLA 384
            |...:..: :..|::.||:||.||.||:.|..:..|||.||.|.:               ::|..
pombe   301 DSAATVIE-RVAEVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYV 364

  Fly   385 VDHLQSKMGRRILLRYRESSMMYESQVGGISLVPLSSNASLNA--ETQLYQKATSLTSMLIGFLG 447
            .|:|||.:....|    .||...|        ||:..:..:|.  :...|.|.:.:..|:..::|
pombe   365 TDNLQSALSLDAL----RSSHPIE--------VPIMHDYEINQIFDAISYSKGSCVIRMVSKYVG 417

  Fly   448 NETFYDGLQRHMWQNSFGSSTPDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPLVTVIR 512
            .:||..|:|:::.::.:|::..:..|.:|...|.:        |:.|.|..||.::|||:::|..
pombe   418 EDTFIKGIQKYISKHRYGNTVTEDLWAALSAESGQ--------DISSTMHNWTKKTGYPVLSVSE 474

  Fly   513 -NGSEV------FLKQGHALNRSSSHLWWIPLTY--LIEGGSLSKNLKPKAWLSPNSHGIKLNDI 568
             |..|:      ||..|.......:.::|.||..  :.:|.::   :..||.||..|..||::..
pombe   475 TNDGELLIEQHRFLSTGDVKPEEDTVIYWAPLKLKTMKDGKAV---VDEKAVLSDRSKKIKVDKE 536

  Fly   569 VPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFNDFRSINVLNRAQIVSDVLFLWNQDLLAWST 633
            ...:  ..||.:..|.|||||.....:.|:.........::|.:||.:::||..|........|:
pombe   537 ALES--YKLNSEQSGIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRAGYGKVSS 599

  Fly   634 ALNVLKYIIDEDEYEPLMAFVVGWTNGFWG-ISTESSFNIA 673
            .|:::|...||..: .:.|.::...||... :..|||..||
pombe   600 TLDLIKTWKDEPNF-VVFAEMLARLNGIKSTLRFESSDIIA 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	120/480 (25%)
		ERAP1_C	574..>652	CDD:338125	20/77 (26%)
		dnaA	630..>701	CDD:234667	13/45 (29%)
ape2	NP_595998.1	PepN	24..871	CDD:223385	173/669 (26%)
		M1_APN_2	27..468	CDD:189008	123/487 (25%)
		ERAP1_C	541..857	CDD:288671	28/100 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010