Protein Alignment CG7653 and T12E12.6

DIOPT Version :9

• Sequence 1: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 707
• Identity: 179/707 - (25%)
• Similarity: 291/707 - (41%)
• Gaps: 138/707 - (19%)

  Fly    23 LLLCLCQVACSAKTQLYDEPRLPAKVKPFHYDIRLLTHLESSANHSYTGIVKISIHA-QKTTNQV 86
            |:|.|.|.|.|          .|..:.|..||:                :.|:.||. ...|..:
 Worm     7 LVLLLFQTANS----------WPHNIIPLSYDL----------------LFKLPIHEFNGFTGSM 45

  Fly    87 VLHVGRVSIESKKITL-------FGETSNYR--------LRSVRFNNDRKYMVVTFNQSLLMGKS 136
            |||....|: |..|||       |...|..|        |:|::...::  :.:.|.:||..|:
 Worm    46 VLHFNLSSL-SDNITLDAVDLHSFRNISLIRSADLTEPTLKSIKILKEK--VELKFEKSLFPGQ- 106

  Fly   137 YVLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMPSFDEPSLKATFNVTM 201
            |:|::........:..:..|.|.       ..:.|: :|...|..|...|..|.|::||.|.:::
 Worm   107 YLLTIGEYNGRIGNSSEALFERR-------NPLLYT-THLQPNHARRLFPCIDHPAVKALFRLSI 163

  Fly   202 GHHKRFQSYGN-MKVQAVLPNREIQDYVWSVHEVTPTIPTHLLAFSV-NNFNCRYSQAASLSPVR 264
            .|.....:..| :.:...:.||:.|.   ::.:.||.:|.:|:|||| .:.|.:.|:..|.. |.
 Worm   164 VHPTDTVAQSNTIAMDVHVENRKWQR---TIFQATPLLPAYLVAFSVMPDSNLQLSRQTSFG-VT 224

  Fly   265 FRTCAQS-------ADVRATSFAAQMAPQILEFLDRVLQVALPLEKIDQLVVDDFPTEAMENFGL 322
            .|...:|       .|....||         |.|..::.|.|||.|||.::|.:: ...|||:|
 Worm   225 VRVNGESRGLVLRVLDCALASF---------EILAGLIDVPLPLNKIDFILVPEY-DGGMENWG- 278

  Fly   323 VVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLAGYF-----KS 382
                  |:.:.|....|.:....:.|||||:||.|..|...:||::.:.|.|.|..:.     |:
 Worm   279 ------HITVSETLATSGDDAHLIYLIAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKA 337

  Fly   383 LAVDHLQSKMGRRILLRYRESSMMYESQVGGISL-VPLSSNASLNAETQLYQKATSLTSMLIGFL 446
            |..|.:  ::.|..|.:|.|..::.:....|.|| :|...|..| .....|.|...|...|...:
 Worm   338 LLTDEI--RLQRFQLAQYVEIQLVEDFLSPGHSLYMPSKINQEL-INRHCYLKGVVLLDTLESVV 399

  Fly   447 GNETFYDGLQRHMWQNS-FGSSTPDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPLVTV 510
            |.:..|..::..:..:| :..:|...::.  |:..:|.||      |..|.:.|....|||.:.|
 Worm   400 GEQFMYSVIKSLVGSHSTYNLTTFTSYFD--QIRVDRNAT------VGQIYEYWYTTGGYPSILV 456

  Fly   511 IRNGSEVFLKQGHALNRSSSHLWWIPLTYLIEGGSLSKNLKPKAWLSPNSHGIKLNDIV--PRNQ 573
            ..||....|:|   |:|.   ||.:.:|        |....|:...|        ..||  ..|.
 Worm   457 ENNGPSSRLQQ---LSRP---LWPLKMT--------STLAIPQFVFS--------ESIVFASENA 499

  Fly   574 WILLNLQAVGYYRVNYDELTWQLLATTLFNDFRSINVLNRAQIVSDVLFLWNQDLLAWSTALNVL 638
            .:|:||....:.|||||.|||..:...:|.:....:.:.|||:|||..:.:..|.:...|.|.
 Worm   500 PLLVNLNFTSFMRVNYDSLTWTAIFKYMFEEPELFSAVGRAQLVSDFCYFYANDKVDNGTILK-- 562

  Fly   639 KYIIDEDEYEPLMAFVVGWTNGFW--GISTESSF-NIAKWLGIAAKWYAEFISYTFD 692
            :.::|....:|....:..| |.:|  ..|.:|.| .:.:.|.:      .|.|.||:
 Worm   563 EAVVDMVYSKPEFFELCDW-NLYWCHSRSDQSLFAQVVRSLAL------RFSSATFE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	117/479 (24%)
		ERAP1_C	574..>652	CDD:338125	23/77 (30%)
		dnaA	630..>701	CDD:234667	15/66 (23%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:387391	108/428 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020