Protein Alignment CG7653 and Y53F4B.20

DIOPT Version :10

• Sequence 1: NP_001356886.1
• Gene: CG7653 / 34935
• FlyBaseID: FBgn0028935
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 140/667 - (20%)
• Similarity: 253/667 - (37%)
• Gaps: 136/667 - (20%)

  Fly    23 LLLCLCQVACSAKTQ------LYDEPRLPAKVKPFHYDIRLLTHLESSANHS---YTG--IVKIS 76
            |||.|..:..|...|      ||.:.|||..:||..||::|...|...::..   :||  ::...
 Worm     5 LLLYLFGIVTSDLHQLLSTRPLYSDDRLPPILKPLSYDLQLQLPLSEVSDPDVPLFTGRCVMHFE 69

  Fly    77 IHAQ----------KTTNQVVLHVGRVSIES-KKITLFGETSNYRLRSVRFNNDRKYMVVTFNQS 130
            |:.|          .|:|:..:....:.::. :.::|........:.:|:..:|.  |.::.:|.
 Worm    70 INQQIGPESAFISDSTSNRARIKFDIIMLDHFENVSLVMNGHELEIFNVQLTDDS--MELSVDQP 132

  Fly   131 LLMGKSYVLSVEFGRPMTMDQRDGYFIRHYINWKTSEKIWY--SVSH--FNRNWIRN----TMPS 187
            :|....|.|::                 |.........|:|  :..|  |..|...|    ..||
 Worm   133 VLFPGRYTLTI-----------------HRYKGLIGSAIYYRDAGEHAVFGSNLFPNRAPAVFPS 180

  Fly   188 FDEPSLKATFNVTMGHHKRFQSYGNMKVQA----VLPNREIQDYVWSVHEVTPTIPTHLLAFSV- 247
            :...:.|.||::||.|     ..|.:.:.:    ..|.:..:::..:....||:|...:|.|.:
 Worm   181 YLASTEKVTFSITMVH-----PVGTLALTSGSNEGAPRKIDENWQMTTFSTTPSITPSMLCFLLL 240

  Fly   248 -------------NNFNCRYSQAASLSPVRFRTCAQSADVRATSFAAQMAPQILEFLDRVLQVAL 299
                         .|.:..|:        |||...:.     |......|.|:|..|..:....:
 Worm   241 PHEYTHIESTYTGVNISVHYN--------RFRVQKEQ-----TKHLLHTATQVLALLKDIFSSLI 292

  Fly   300 PLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGM 364
            |:.|||.:.:::..:.|.  ||.:|       :.|....|.:....::::|..:|..|......:
 Worm   293 PVPKIDIITMNEVSSTAC--FGSIV-------VSEVQFFSADYANQVKMLATWLAKQWIGGYAAI 348

  Fly   365 DSYSDLWLTEGLAGYFKSLAVDHLQSKMGRRILLRYRESSMMYESQVGGISLVPLSSNASLNA-- 427
            ...|:|.|.|.|..:.    .|.:..:|......|....:.:|.|:    ::........|:.
 Worm   349 SEGSELCLQEDLVAFI----ADKVIKRMTNDEFTRLGHLAKIYLSE----TIFTAGDTLKLDEHP 405

  Fly   428 -ETQLYQ----KATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSSTPDLFWRSLQLASEREATFD 487
             |.::::    |..::...:...:|.::....:...::.:..||      :.|..|.....:|.|
 Worm   406 NEFEIFEKCGLKGVAMLESIESLIGEKSMISKINEMIYNSKKGS------YSSRTLYGLLNSTVD 464

  Fly   488 KTWDVKSIMDTWTMQSGYPLVTVIR---------NGSEVFLKQGHALNRSSSHLWWIPLTYLIEG 543
            :...|..::..|....|.|.:.|.|         |||.:.:|.| |.......||.:||.:
 Worm   465 EDIYVSQLLHYWHEHGGLPYMNVDRLANSIKITQNGSNMTVKNG-AGTWERMPLWPLPLKF---- 524

  Fly   544 GSLSKNLKPKAWLSPNSHGIKLNDIVPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFNDFRSI 608
                ...|....:.. ||||.|:.|  |:..|..||....|||||||..||:.:.|.|..:..|.
 Worm   525 ----TEFKLPIQIMV-SHGIHLSPI--RDGLIFSNLGFTNYYRVNYDIDTWREIKTVLTENATSY 582

  Fly   609 NVLNRAQIVSDVLFLWN 625
            .:..|.|:|||..:.::
 Worm   583 TLRERFQLVSDFCYFYS 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	84/496 (17%)
		ERAP1_C	574..>652	CDD:463368	20/52 (38%)
		dnaA	630..>701	CDD:455861
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:472708	54/297 (18%)
		ERAP1_C	552..>593	CDD:463368	17/40 (43%)