DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7653 and aopep

DIOPT Version :9

Sequence 1:	NP_001356886.1	Gene:	CG7653 / 34935	FlyBaseID:	FBgn0028935	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_012827019.1	Gene:	aopep / 100145347	XenbaseID:	XB-GENE-986050	Length:	822	Species:	Xenopus tropicalis

Alignment Length:	566	Identity:	107/566 - (18%)
Similarity:	189/566 - (33%)	Gaps:	200/566 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 TMPSFDEPSLKATFNVTMGHHKRFQSYGNMKVQAVLPNREIQDYVWSVHEVTPTIPTHLLAFSVN 248
            |||.   |:  :||.:.:|..:..:...:..::                  |..:.|.|.   :|
Frog   330 TMPM---PA--STFTIAVGCWEEIKENSSCNIK------------------TSDLSTPLY---IN 368

  Fly   249 NFN------CRYSQAASLSPVRF---RTCAQSADVRATSFAA-----QMAPQILEFLDRVLQVA- 298
            |.:      |::.:    .|.||   ..||| |.:....||:     |.:..:|..:...|:.|
Frog   369 NGSRLKEQKCKHME----YPCRFSLPEACAQ-AIIPHRVFASHVLFKQCSEVLLPLVSPCLEAAH 428

  Fly   299 -----LPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIAHEMAHMWF 358
                 .|..::|.|||.       .||..:...|.|::......:..........:.||:||.||
Frog   429 AVLGTHPFPRLDILVVP-------SNFSSLGMASPHIIYLSQSVLYGSNHLCATRLCHEIAHAWF 486

  Fly   359 DNLLGMDSYSDLWLTEGLAGYFKSLAVDHLQ--------SKMGRRILLRYRE-SSMMYESQVGGI 414
            ..::|...:::.|::||.|.:.:.:.:.::|        .:...:.|||:|. :..:.:||....
Frog   487 GLVIGARDWTEEWISEGFATHLEDVFLANVQKLPQEEARDQQKLKALLRWRRLTDELKDSQEELQ 551

  Fly   415 SLVPLSSNA-------------SLNAETQL----YQKATSLTSMLIGFLGNETFYDGLQR----- 457
            .|.|...|.             .||||...    |.|...|...|....|.:.::..|::
Frog   552 ILRPHGENTGKVNESGASVVRHGLNAEKTFMQVHYLKGYFLLRSLANTTGQDAYFAFLRQFVNTC 616

  Fly   458 -----------HMWQNSFGSSTPDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPL---- 507
                       ||    ...|.|:|..:.|              .|::|.:.|....|.|.
Frog   617 HGQLILSKDFLHM----LFESVPELNRQHL--------------CVQAIYEIWLDTPGIPQPLLG 663

  Fly   508 -------VTVIRNGSEVFLKQGHALNRSSSHLWWI--------------PLTYLIEGGSLSKNL- 550
                   ..:::..:|..||             ||              |.|...:...|.:.|
Frog   664 ESRTWKGCRLVQQVNEEVLK-------------WIRFDQRNKKCSRRKRPHTEEFDEKILPEQLV 715

  Fly   551 ---------KPKAWLSP-------NSHGIKLNDIVPRNQWILLNL------------------QA 581
                     :|   |.|       |::.::..|...|::|..|.:                  ||
Frog   716 LLLDLLLEERP---LLPRTLRCLENTYRLRNQDAEVRHRWCELVVKHKYTVAYKDVEKFLHEDQA 777

  Fly   582 VGYY-----RVNYDELTWQLLATTLFNDFRSINVLNRAQIVSDVLF 622
            :|.|     .|| ::...|.:|...|...|....::..::|.::||
Frog   778 MGVYLYGELMVN-EDARQQEIARRCFAAVRDEMDISCVKVVGEMLF 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7653	NP_001356886.1	M1_APN-Q_like	52..500	CDD:341064	74/377 (20%)
		ERAP1_C	574..>652	CDD:338125	15/72 (21%)
		dnaA	630..>701	CDD:234667
aopep	XP_012827019.1	GluZincin	233..652	CDD:387391	74/377 (20%)
aopep	XP_012827019.1	Leuk-A4-hydro_C	731..821	CDD:378127	16/90 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910