DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tektin-A and Tekt4

DIOPT Version :9

Sequence 1:	NP_001260476.1	Gene:	Tektin-A / 34934	FlyBaseID:	FBgn0028902	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_082227.1	Gene:	Tekt4 / 71840	MGIID:	1919090	Length:	447	Species:	Mus musculus

Alignment Length:	446	Identity:	142/446 - (31%)
Similarity:	230/446 - (51%)	Gaps:	16/446 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 PQQGD--ELPHKDQLMPMGPIGPWASGKVDWSPMAGITGTRPVVDRYSITRYSPNEWRTRNHETV 200
            ||..|  |||.|:..:........:||..    .||          :...:|..:||...::...
Mouse    14 PQSIDVCELPRKEYEVACNTGAYTSSGLA----TAG----------FRTAKYLRDEWFQNSYARY 64

  Fly   201 QVVNASLGRADKNRFSSTTEFLRLSALVDKSQKETTDKLRIRSQLIGKWKNTLENAIKAMADEIS 265
            ....|....:::.|..|........||..::|.::|.|:..|.:.:..||:.|:..|..::.|..
Mouse    65 HQAFADRDYSERQRHESGQLVAETGALAQRTQLDSTRKVGERLEDMHCWKSELQREIDELSSETD 129

  Fly   266 TMEVERIKLRKSMVVLGVPESIAKECIEKRATRPDTELVRDQVEEELVNELALIAEIRRLLMKTL 330
            .|..::::|::::....||.|||.:.::.|..|...:||||.||.||:.|..||..|:.||.:|:
Mouse   130 LMMAQKLRLQRALDATSVPYSIATDNLQCRERRQHPDLVRDYVEVELLKETELIRNIQELLKRTI 194

  Fly   331 DDFNSQQVENRTARQRLEYDWSDKKESYEIDTINTGLNNCSRTIMFRPGAVRQPPEQASEKYWEH 395
            .....|...||..::..|.:||||.|.|.||...:...|.|..:.|.|.:.:.....::.:.|..
Mouse   195 GQAVDQIRLNREHKESCEMNWSDKVEVYNIDDTCSRYTNESTQVQFYPHSSKFEESASTPETWAK 259

  Fly   396 FSMETLDECEKCRLKSVALRNTLNSTLMNAARDIRTQADVVEKALTSRINCTQEAVQRFENDLKN 460
            |:.:.|...|:.||.||.||..::..|.:.|.|:|.|.|.|..|.:||.....:::|:.:..|:.
Mouse   260 FNHDNLLRAERERLASVNLRKLIDCILRDTAEDLRLQCDAVNSAFSSRCQELDDSLQKLQYHLRK 324

  Fly   461 ILQGTADVENRIEQMKRRINSFDSSMKVAQTRMDNRSYRPNVENCRDLAQQELIDGVHTIQSSVS 525
            .|....|.|::|..:|:.|...::.::|||||:..||:|||||.|||.||..|:..|..:..|:.
Mouse   325 TLTEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQRSHRPNVELCRDNAQFRLLSEVEELNMSLR 389

  Fly   526 ALLHELEEAERVKTDLVNSRARLEREIMLKRRSLFIDRERCMLMRSYYPSANTLSG 581
            ||..:|::||:...:|.:||..||::|.:|..||||||::||..|:.|||...|:|
Mouse   390 ALKEKLQDAEQALRNLEDSRMSLEKDIAVKTNSLFIDRQKCMTHRNRYPSVLQLAG 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tektin-A	NP_001260476.1	Tektin	192..571	CDD:281184	123/378 (33%)
Tekt4	NP_082227.1	Tektin	56..434	CDD:308655	123/377 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59762
OrthoDB	1	1.010	-	-		D264325at33208
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108956
Panther	1	1.100	-	-	LDO	PTHR19960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.790