DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tektin-A and Tekt4

DIOPT Version :9

Sequence 1:	NP_001260476.1	Gene:	Tektin-A / 34934	FlyBaseID:	FBgn0028902	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001013987.1	Gene:	Tekt4 / 302991	RGDID:	1308075	Length:	447	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	143/466 - (30%)
Similarity:	234/466 - (50%)	Gaps:	25/466 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 EVQFARSMDPEADDLRNPPCYLPQQGDELPHKDQLMPMGPIGPWASGKVDWSPMAGITGTRPVVD 180
            ||...:...|::.|:    |.|||:..|:...        .|.:.|        ||:     ...
  Rat     5 EVLLTKEPAPQSIDV----CELPQKKYEVACN--------TGAYTS--------AGL-----ATA 44

  Fly   181 RYSITRYSPNEWRTRNHETVQVVNASLGRADKNRFSSTTEFLRLSALVDKSQKETTDKLRIRSQL 245
            .:...:|..:||...::.......|....:::.|..|.........|..::|.::|.::..|.:.
  Rat    45 GFRTAKYLMDEWFQNSYARYHQAFADRDYSERQRHESKQLAAETGELAYRTQLDSTRRVGERLED 109

  Fly   246 IGKWKNTLENAIKAMADEISTMEVERIKLRKSMVVLGVPESIAKECIEKRATRPDTELVRDQVEE 310
            :..||:.|:..|..::.|...|..::::|::::..|.||.|||.:.::.|..|...:||||.||.
  Rat   110 MHCWKSELQREIDELSSETDQMMAQKLRLQRALDALSVPFSIATDNLQCRERRQHPDLVRDYVEV 174

  Fly   311 ELVNELALIAEIRRLLMKTLDDFNSQQVENRTARQRLEYDWSDKKESYEIDTINTGLNNCSRTIM 375
            ||:.|..||..|:.||.:|:.....|...||..::..|.:||||.|.|.||.......|.|..:.
  Rat   175 ELLKETELIRNIQELLKRTMGQAVGQIRLNREHKENCEINWSDKVEVYNIDDTCARYTNESTQVQ 239

  Fly   376 FRPGAVRQPPEQASEKYWEHFSMETLDECEKCRLKSVALRNTLNSTLMNAARDIRTQADVVEKAL 440
            |.|.:.:.....::.:.|..|:.:.|...|:.||.||.||..::..|.:.|.|:|.|.|.|..|.
  Rat   240 FYPHSSKFEESASTPETWGKFTQDVLLRAERERLASVNLRKLIDCILRDTAEDLRLQCDAVNLAF 304

  Fly   441 TSRINCTQEAVQRFENDLKNILQGTADVENRIEQMKRRINSFDSSMKVAQTRMDNRSYRPNVENC 505
            ::|.....:|.|:.:..|..||....|.|::|..:|:.|...::.::|||||:..||:|||||.|
  Rat   305 SNRCEELNDARQKLQYHLLKILSEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQRSHRPNVELC 369

  Fly   506 RDLAQQELIDGVHTIQSSVSALLHELEEAERVKTDLVNSRARLEREIMLKRRSLFIDRERCMLMR 570
            ||.||..|:..|..:..|:..|..:|::||:...:|.:||..||::|.:|..||||||::||..|
  Rat   370 RDNAQFRLMSEVEELNMSLKVLKEKLQDAEQALRNLEDSRMSLEKDIAVKTNSLFIDRQKCMTHR 434

  Fly   571 SYYPSANTLSG 581
            :.|||...|:|
  Rat   435 NRYPSVLQLAG 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tektin-A	NP_001260476.1	Tektin	192..571	CDD:281184	122/378 (32%)
Tekt4	NP_001013987.1	Tektin	56..434	CDD:281184	122/377 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59762
OrthoDB	1	1.010	-	-		D264325at33208
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108956
Panther	1	1.100	-	-	LDO	PTHR19960
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.790