DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tektin-A and Tekt3

DIOPT Version :9

Sequence 1:	NP_001260476.1	Gene:	Tektin-A / 34934	FlyBaseID:	FBgn0028902	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001019910.1	Gene:	Tekt3 / 287392	RGDID:	1310582	Length:	490	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	124/469 - (26%)
Similarity:	221/469 - (47%)	Gaps:	25/469 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 YLPQQG-------DELPHKDQLMPMGPIGPWASG-----KVDWSPMAGITGTR---------PVV 179
            :||..|       :..||::....:..  ||...     ..::..:|.::.|.         |.|
  Rat    22 FLPAIGTLTSSYRNRFPHRNLTHSLSL--PWRPSTYYKTAYNYPTLAPLSSTSQSVCESTMLPFV 84

  Fly   180 DRYS--ITRYSPNEWRTRNHETVQVVNASLGRADKNRFSSTTEFLRLSALVDKSQKETTDKLRIR 242
            ...:  .|||:|::|........|..|.|...:::.|..::.........:.|:|.::|..|..|
  Rat    85 SNRTTLFTRYTPDDWYRSTLVGFQESNCSRHNSERLRVDTSRLIQDKYQQIRKTQADSTQNLGER 149

  Fly   243 SQLIGKWKNTLENAIKAMADEISTMEVERIKLRKSMVVLGVPESIAKECIEKRATRPDTELVRDQ 307
            ...|..||:.:.:.:..|..|.:.:...:.:|.:.::....|..:|:||:..|..|...:||.|:
  Rat   150 VNDIAFWKSEIIHELDEMIGETNALTDIKRRLERGLIETDAPLQVARECLFHREKRMGIDLVHDE 214

  Fly   308 VEEELVNELALIAEIRRLLMKTLDDFNSQQVENRTARQRLEYDWSDKKESYEIDTINTGLNNCSR 372
            .|:||:.|:..:...:..:.:.||...:|...:|:|:..||.|.|||:.:..||.....|.|.|:
  Rat   215 AEKELLTEVETVLCCQERMRRHLDKAIAQLASDRSAQHELEKDLSDKQAALRIDDKCKHLRNTSQ 279

  Fly   373 TIMFRPGAVRQPPEQASEKYWEHFSMETLDECEKCRLKSVALRNTLNSTLMNAARDIRTQADVVE 437
            .:.:..|........:..:.|..|:.:.:...:..|..|..||....:.|:..|.::..|.:.|.
  Rat   280 GVSYFRGVENVDATVSVPESWAKFTDDNVLRSQSERAASAKLREDTENLLIVIANEMWNQFNKVN 344

  Fly   438 KALTSRINCTQEAVQRFENDLKNILQGTADVENRIEQMKRRINSFDSSMKVAQTRMDNRSYRPNV 502
            .|.|:||..|.:|..:....|...||.....|..||.:::.|....:.:||||||:|.|:.|||:
  Rat   345 VAFTNRIAETVDAKNKIHIHLSKTLQEIFQTEMAIESIRKAIKEKSAFLKVAQTRLDERTRRPNI 409

  Fly   503 ENCRDLAQQELIDGVHTIQSSVSALLHELEEAERVKTDLVNSRARLEREIMLKRRSLFIDRERCM 567
            |.|||:||..|::.|:.:..::..|...|.::|.....|.:::|.||.::.:|..:|:||:|:||
  Rat   410 ELCRDIAQLRLVNEVYEVDETIQTLQQRLRDSEDTLQSLAHTKATLEHDLAVKANTLYIDQEKCM 474

  Fly   568 LMRSYYPSANTLSG 581
            .||:.|||...|.|
  Rat   475 SMRNSYPSTLRLVG 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tektin-A	NP_001260476.1	Tektin	192..571	CDD:281184	103/378 (27%)
Tekt3	NP_001019910.1	Tektin	99..477	CDD:281184	102/377 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59762
OrthoDB	1	1.010	-	-		D264325at33208
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.790