Protein Alignment t-Grip91 and Tubgcp2

DIOPT Version :10

• Sequence 1: NP_723933.1
• Gene: t-Grip91 / 34931
• FlyBaseID: FBgn0028901
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_598516.2
• Gene: Tubgcp2 / 74237
• MGIID: 1921487
• Length: 905
• Species: Mus musculus
• Alignment Length: 1032
• Identity: 196/1032 - (18%)
• Similarity: 359/1032 - (34%)
• Gaps: 283/1032 - (27%)

  Fly  1000 DQDELSPILGQISKTVSDVKINILNEVDKSLSEITVKSVSAILQKRKSKEYFSNQHKSQDFDYLT 1064
            |.:||..:|.......::|.|::|   .|:.:.....:|||...|.|..|:   ....:||....
Mouse     9 DVNELLSLLRIHGGDGAEVYIDLL---QKNRTPYVTTTVSAHSAKVKIAEF---SRTPEDFLKKY 67

  Fly  1065 DDLSGESVVKVSPLKNV------DRFISEWTQKNPSDSILGKPYPKNLRYTSETSELSESSERES 1123
            |:|..::...:.||..:      |:...::.|:|..:.       ..|..::.||..:..|...:
Mouse    68 DELKSKNTRNLDPLVYLLSKLTEDKETLQFLQQNAKER-------AELAASAATSNTTSFSIPVA 125

  Fly  1124 LSRNSNQILYLCKSCNAMLNYSEEVNKYFAGDFCINKKKFKVSDRNDLS---NLERKFRQKWHHQ 1185
            .|:.|.|.|             ||:.|...          .||..:.|.   .|.||..:
Mouse   126 ASKMSTQEL-------------EELRKQLG----------SVSTGSTLQQSLELTRKMLR----- 162

  Fly  1186 RYVIAAPRAIIKSFKSNPAYGWSPDDPNAPDFYEQLDQFFEVTGQKKYRAGCDILFASIQLRLSQ 1250
                                    |..|..:..:.|..|.....::...|| |.|..|   .||.
Mouse   163 ------------------------DKQNKKNSGQPLPVFPAWVYERPTLAG-DFLIGS---GLSS 199

  Fly  1251 VLKRIVRHAPKNTSFPDLITIVGVAQLEQLLTRKERAAYESMRWQSRDKGDQDLSAESLFTDALH 1315
                            |.:..:|...|         |:.||                ::..|.|:
Mouse   200 ----------------DTVLPIGTLPL---------ASQES----------------AVVEDLLY 223

  Fly  1316 GMMGYGSPHLKLSSLTGRLQ---LRSPHHQESISE--SYLLLALGHFGYFYRELKEHLARLAEQG 1375
            .::|....::....|.||..   |..|:...||.|  :.:|.....:....|.::|..:  .|.|
Mouse   224 VLVGVDGRYITAQPLAGRQNRTFLVDPNLDLSIRELVNRILPVAASYSTVTRFIEEKSS--FEYG 286

  Fly  1376 DT----ALALRKCLQKYLLNLHQFYDVQKRNPSSLLSLYRRTRDFQRNFEWLLEVFNNVQKAK-- 1434
            ..    |.|:|..:::||:.:.|...:.::...||..|:...:...|..:.|..:..:|.|.:
Mouse   287 QVNHALAAAMRTLVKEYLILVTQLEQLHRQGLLSLQKLWFYIQPAMRTIDILASLATSVDKGECV 351

  Fly  1435 --SIVVYLYKESSRRTG--YQRNLLLKWLRLVIQPLIYNLHIWLLNGRLPSTDHD---MFVIEQT 1492
              |.:..|:..|...||  ..:.|.|...:....|....|..|:..|.:    ||   .|::|:.
Mouse   352 GGSTLSLLHDRSFNYTGDSQAQELCLYLTKAASAPYFEILEKWIYRGII----HDPYSEFMVEEH 412

  Fly  1493 KYSKV-------DEFWEKRYRITESFSGIFDPQLSEILISVGKTMEYSEKYLAINFE-----SCV 1545
            :..|.       |::|::||.:.......|..:::..::|.|       |||.:..|     :|.
Mouse   413 ELRKEKIQEDYNDKYWDQRYTVLPQQIPSFLQKVAGKILSTG-------KYLNVVRECGHDVTCP 470

  Fly  1546 PRKEVRCMLLETFDKFLRHGDQ-EPLYNFVRNLHLEI---SSKVLKYLRKTKINPEYLFSGLHKY 1606
            ..||:...|.|.     .:.:| |..:|:...:.|:.   ..:::.:||..|           :|
Mouse   471 VAKEIIYTLKER-----AYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIK-----------RY 519

  Fly  1607 IMLTDLNFIMEFINALESVLGEP------------------ESSFNIQLFNE------MKNKMLH 1647
            .::...:|.:.|::..|..|.:|                  .|:.|...|.:      |.:.::.
Mouse   520 FLMDQGDFFVHFMDLTEEELRKPVEDIILTRLEALLELALRMSTANTDPFKDDLKIELMPHDLIT 584

  Fly  1648 KSVRDIYIDKSESEGSRCWSKLILRWKMPTHWRALLGEDSKAYEVIFKAMWRFHYVYYV------ 1706
            :.:|.:.|:..:.             |..||        :...|:....:..|.:.|.|
Mouse   585 QLLRVLAIETKQE-------------KAMTH--------ADPTELTLSGLEAFSFDYMVKWPLSL 628

  Fly  1707 -LNER-VHRQQIRFQNHIECTYFEG-------LNDT--------LKCFSKLTNACLRLMNVL--M 1752
             :|.: :.|.|:.|::...|.:.|.       .|.|        .|.|:.......|::|.:  :
Mouse   629 IINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHALHSAKWFAGAFTLRQRMLNFVQNI 693

  Fly  1753 EYFLDY-LLEPAFARLLWYCRNAITVDELLVANRKYLKTIILGSLQTK-NLRKYLERLYDLILQL 1815
            :|::.: ::||.:..|....::|..:|::|..:..:|...:...:.|. .|.|...:|..:.:..
Mouse   694 QYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCMLTNPELLKVFSKLMSVCVMF 758

  Fly  1816 DNKHWKF------------LRLCQTSVE--------YVIRVRKEKPQSIFSTYYRERMLQFRWTC 1860
            .|...||            |.|.|.||:        ...|.|||..:...|.:.....|     .
Mouse   759 TNCMQKFTQSMKLDSELGRLTLDQGSVQGPPTETERIEDRPRKELTRKHLSEHVDAPQL-----A 818

  Fly  1861 QNYSDVINEMKDQFDLAMISFL--LCLHLADD--DSLRSLAKRLDPEHYYMEKDNRL 1913
            ..:...||.....|...::..|  |.::...|  ..:.|:..|||...:|.|:..||
Mouse   819 SGFEATINNFDKNFSAHLLDLLARLSVYSTSDCEHGMASVISRLDFNGFYAERLERL 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip91	NP_723933.1	GCP_N_terminal	1312..1591	CDD:465456	66/312 (21%)
		GCP_C_terminal	<1690..1906	CDD:461187	52/266 (20%)
Tubgcp2	NP_598516.2	GCP_N_terminal	218..506	CDD:465456	65/305 (21%)
		GCP_C_terminal	509..868	CDD:461187	70/395 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	877..905