Protein Alignment t-Grip91 and tubgcp4

DIOPT Version :10

• Sequence 1: NP_723933.1
• Gene: t-Grip91 / 34931
• FlyBaseID: FBgn0028901
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_001128602.1
• Gene: tubgcp4 / 557155
• ZFINID: ZDB-GENE-081022-124
• Length: 668
• Species: Danio rerio
• Alignment Length: 744
• Identity: 143/744 - (19%)
• Similarity: 241/744 - (32%)
• Gaps: 223/744 - (29%)

  Fly  1294 WQSRD--KGDQDL----SAESLFTDALHGMMGYGSPHLKLSSL----TGRLQLRSPHHQESISES 1348
            |..|:  :..|||    .:|   |..|:.:...|:.:::.:..    ||.:. :..|:....|:|
Zfish    19 WNKRNGLQVSQDLPFLHPSE---TSVLNRLCKMGTDYVRFTEFIEQHTGHVH-QQEHYSSQPSQS 79

  Fly  1349 YLLLALGHFGYFYRELKEHLARLAEQGDTALALRKCLQKYLLNLHQFYDVQKR---NPS-SLLSL 1409
                  |..|.:.|..             ...|...||.|...|   .|::|.   :|. |:..:
Zfish    80 ------GLHGIYLRAF-------------CTGLHSMLQPYRQAL---LDLEKEFLGDPHLSISHV 122

  Fly  1410 YRRTRDFQRNFEWLLEVFNNVQKAK----SIVVYLYKESSRRTGYQRNLLLKWLRLVIQPLIYNL 1470
            ......||..|..::.|...::..|    .|:..:||.|.......|..|.|.|.:....:...|
Zfish   123 NYMLEQFQLLFPSVMVVVETIKSQKIHGCQILETVYKHSCGGLPPVRMALEKILAVCHGVMYKQL 187

  Fly  1471 HIWLLNGRLPSTDHDMFVIE------QTKYSKVDEFWEKRYRITE--SFSGIFDPQLSEI----L 1523
            ..|:|:|.|.....:.||.:      .|...:.||         |  ...|:...||.|:    |
Zfish   188 AAWMLHGLLLDQSEEFFVKQGPSAGGATAAQEEDE---------EDLGIGGLSGKQLRELQDLRL 243

  Fly  1524 ISVGKTMEYSEKYLAINFE---SCVPRKEVRCMLL--ETFDKFLRHGD----------------- 1566
            |.....:..|.:..::..|   |.:|.:....:|.  |:...|..|..
Zfish   244 IEEENMLAPSLQQFSLRVEMLPSYIPVRVAEKILFVGESVQMFENHNQSPSRAGSILKHQEDMFA 308

  Fly  1567 -------QEPLYNFV--RNLHLEISSKVLKYLRKTKINPEYLFSGL---HKYIMLTDLNFIMEFI 1619
                   |:||::.|  .||...|.|.|.::|....:....|...|   ..:.:|........||
Zfish   309 AELHRLKQQPLFSLVDFENLVDGIRSTVAEHLWTLMVEESDLLGQLKIIKDFFLLGRGELYQVFI 373

  Fly  1620 NALESVLGEPESSFNIQLFNEMKNKMLHKSVRD---------IYID---------KSESEGSRCW 1666
            :..:.:|..|.|:......|....:..||.:.|         :.||         ....||:...
Zfish   374 DLAQHMLKTPPSAVTEHDVNVAFQQAAHKVLLDDDNLLPLLHLTIDYHGKESKEGSGNREGTTPP 438

  Fly  1667 SKLILRWKMPTHWRALLGEDSKAYEVIFKAMWRFHYVY-------------YVLNERVHRQQIRF 1718
            .:...|...||.|.||        .:.:|..|..|.::             |:|:.|      |.
Zfish   439 QESSPREAPPTGWAAL--------GLAYKVQWPLHILFTPAVLEKYNVVFRYLLSVR------RV 489

  Fly  1719 QNHIE-CTYFEGLNDTLKCFSKLTNAC-LRLMNVL------MEYFLDY-LLEPAFARLLWYCRNA 1774
            |:.:: |...:.....||  |..|:|. .||.|.:      ::|:|.. :||..|::||....:.
Zfish   490 QSELQHCWALQMQRKHLK--SNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLQQINST 552

  Fly  1775 ITVDELLVANRKYLKTIILGS-LQTKNLRKYLERLYDLILQLDNKHWKFLRLCQTSVEYVIRVRK 1838
            ...:.:.:|:..:|..::..| :..|.:...|..:.||
Zfish   553 RDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDL--------------------------- 590

  Fly  1839 EKPQSIFSTYYRERMLQFRWTCQNYSDVINEMKDQFD-------------LAMISFLLCLHLAD- 1889
                                 |.|:..::::.....|             .:..||||...|:.
Zfish   591 ---------------------CHNFCSLVSQNLGSLDERGTAQLDILVKGFSRQSFLLFKILSSV 634

  Fly  1890 -----DDSLRSLAKRLDPEHYYMEKDNRL 1913
                 :..|..|..|||...||.:....|
Zfish   635 RNHQINSDLAQLLLRLDYNKYYTQAGGTL 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip91	NP_723933.1	GCP_N_terminal	1312..1591	CDD:465456	67/333 (20%)
		GCP_C_terminal	<1690..1906	CDD:461187	44/257 (17%)
tubgcp4	NP_001128602.1	GCP_N_terminal	2..347	CDD:465456	74/362 (20%)
		GCP_C_terminal	350..656	CDD:461187	66/369 (18%)