Protein Alignment t-Grip91 and Tubgcp4

DIOPT Version :10

• Sequence 1: NP_723933.1
• Gene: t-Grip91 / 34931
• FlyBaseID: FBgn0028901
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_700436.1
• Gene: Tubgcp4 / 51885
• MGIID: 1196293
• Length: 667
• Species: Mus musculus
• Alignment Length: 706
• Identity: 145/706 - (20%)
• Similarity: 252/706 - (35%)
• Gaps: 185/706 - (26%)

  Fly  1311 TDALHGMMGYGSPHLK----LSSLTGRLQLRSPHHQESISESYLLLALGHFGYFYRELKEHLARL 1371
            |..|:.:...|:.:::    :...||.:| :..||.....:.      |..|.:.|..
Mouse    39 TSVLNRLCRLGTDYIRFTEFIEQYTGHVQ-QQDHHPPQQGQG------GLHGIYLRAF------- 89

  Fly  1372 AEQGDTALALRKCLQKY---LLNLHQFYDVQKRNPSSLLSLYRRTRD-FQRNFEWLLEVFNNVQK 1432
                  ...|...||.|   ||:|.|.:   ..:|...:|....:.| ||..|..::.|...::.
Mouse    90 ------CTGLDSVLQPYRQALLDLEQEF---LADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKS 145

  Fly  1433 AK----SIVVYLYKESSRRTGYQRNLLLKWLRLVIQPLIYNLHIWLLNGRLPSTDHDMFVIEQ-- 1491
            .|    .|:..:||.|.......|:.|.|.|.:....:...|..|:|:|.| ...|:.|.|:|
Mouse   146 QKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLL-LDQHEEFFIKQGP 209

  Fly  1492 ---TKYSKVDEFWEKRYRITESFSGIFDPQLSEI----LISVGKTMEYSEKYLAINFE---SCVP 1546
               |..::::|..|..     ...|:...||.|:    ||.....:..|.|..::..|   |.:|
Mouse   210 SSGTLSAQLEEDEEDL-----GIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIP 269

  Fly  1547 RKEVRCMLL--------------------------ETFDKFLRHGDQEPLYNFV--RNLHLEISS 1583
            .:....:|.                          :||...|....|:||::.|  ..:...|.|
Mouse   270 VRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRS 334

  Fly  1584 KVLKYLRKTKINPEYLFSGL---HKYIMLTDLNFIMEFINALESVLGEP-----ESSFNIQLFNE 1640
            .|.::|.|..:....|...|   ..:.:|........||:..:.:|..|     |...|: .|.:
Mouse   335 TVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNV-AFQQ 398

  Fly  1641 MKNKML--------------------HKS---------VRDIYIDKSESEGSRCWSKLILRWKM- 1675
            ..:|:|                    ||:         .|:....::.|.|   |:.|.|.:|:
Mouse   399 SAHKVLLDDDNLLPLLHLTIEYHGKDHKADATQPREVPSRETSPREAPSSG---WAALGLSYKVQ 460

  Fly  1676 -PTH---WRALLGEDSKAYEVIFKAMWRFHYVYYVLNERVHRQQIRFQNHIECTYFEGLNDTLKC 1736
             |.|   ..|:|    :.|.|:||         |:|:  |.|.|...|:   |...:.....||
Mouse   461 WPLHILFTPAVL----EKYNVVFK---------YLLS--VRRVQAELQH---CWALQMQRKHLK- 506

  Fly  1737 FSKLTNAC-LRLMNVL------MEYFLDY-LLEPAFARLLWYCRNAITVDELLVANRKYLKTIIL 1793
             |..|:|. .||.|.:      ::|:|.. :||..|::||....:....:.:.:|:..:|..::.
Mouse   507 -SNQTDAVKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLA 570

  Fly  1794 GS-LQTKNLRKYLERLYDLILQLDNKHWKFLRLCQTSVEYVIRVRKEKPQSIFSTYYRERMLQFR 1857
            .| :..|.:...|..:.||.      | .|..|...::..:......:...:...:.|:..|.|:
Mouse   571 QSFILLKPVFHCLNEILDLC------H-SFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFK 628

  Fly  1858 WTCQNYSDVINEMKDQFDLAMISFLLCLHLADDDSLRSLAKRLDPEHYYMEKDNRL 1913
                    :::.:::             |..:.| |..|..|||...||.:....|
Mouse   629 --------ILSSVRN-------------HQINSD-LAQLLLRLDYNKYYTQAGGTL 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip91	NP_723933.1	GCP_N_terminal	1312..1591	CDD:465456	69/330 (21%)
		GCP_C_terminal	<1690..1906	CDD:461187	46/224 (21%)
Tubgcp4	NP_700436.1	GCP_N_terminal	2..347	CDD:465456	71/336 (21%)
		GCP_C_terminal	350..655	CDD:461187	71/357 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..446		3/21 (14%)