Protein Alignment t-Grip91 and Grip75

DIOPT Version :10

• Sequence 1: NP_723933.1
• Gene: t-Grip91 / 34931
• FlyBaseID: FBgn0028901
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 132/745 - (17%)
• Similarity: 255/745 - (34%)
• Gaps: 221/745 - (29%)

  Fly  1258 HAPKNTSFPDLITIVGVAQLEQLLTRKERAAYESMRWQSRDKGDQDLSAESLFTDALHGMMGYGS 1322
            |..:...|.|:|.|:.|.|      ..|:..:.|.| :|...|:        ..|:|||.
  Fly    33 HPCEREIFMDIIKIIKVYQ------EVEQFTHSSGR-KSDTHGE--------LPDSLHGY----- 77

  Fly  1323 PHLKLSSLTGRLQLRSPHHQESISESYLL-LALGHFGYFYRELKEHLARLAEQGDTALALRKCLQ 1386
                                      ||| ||.|    ....|:|:.|.:..           |:
  Fly    78 --------------------------YLLNLAKG----IEMALEEYYAEIGR-----------LE 101

  Fly  1387 KYLLNLHQFYDVQKRNPSSLL--SLYRR--TRDFQRNFEWLLEVFNNVQKAKSIVVYLYKESSRR 1447
            ||.|.       .:||..|.:  :||.:  ...|.||....:.|.|   ....::::...:....
  Fly   102 KYCLG-------NERNSLSYVYNALYAKFPLLVFMRNLITEIHVLN---LRGCVLLHNLHQQCEH 156

  Fly  1448 TGYQRNLLLKWLRLVIQPL----IYNLHIWLLNGRLPSTDHDMFV-------IEQTKYSK----- 1496
            ...|   |.|.::::::|:    ..:|..|||.|.:.....:.|:       ::.:.:||
  Fly   157 GDIQ---LEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCS 218

  Fly  1497 --------VDEFWEKRYRITES-FSGIFDPQLSEILISVGKTMEYSEKYLAINFESCVPRKEVRC 1552
                    .|..|:  |.:..| ..|.|...|:|.::.||:|:...:....:..::.......:.
  Fly   219 LLSAEKNPEDYIWQ--YEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKL 281

  Fly  1553 MLLETFDKF-LRHGDQEPLYNFVRNLHLEISSKVLKYLRKTKINPEYLFSGLHKYIMLTD----- 1611
            ..|::.|.: |..|.:...:..|.:|..|.:..|.: |.|..|:.:...|.....|.:.:
  Fly   282 AELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFR-LEKVIIDIKNYVSARLSEIAVNEVDLER 345

  Fly  1612 -LNFIMEFINALESVLGEPESSFNIQLFNEMKNKMLHKSVRDIYIDKSESEGSRCWSKLILRWKM 1675
             :..|.:|.     :||..|  |.::..::|...|      :.|.::              |:|.
  Fly   346 QMGLIKDFF-----LLGRGE--FYLEFCSQMVGTM------ETYREE--------------RFKN 383

  Fly  1676 PTHWRAL------LGEDSKAYEVIFKAMWRFHYVYYVLNERVHRQQIRFQNHIECTYFEGLNDTL 1734
            .|....|      :.:|...:.:|                 ..|......:..:..:.:||  :|
  Fly   384 VTRSFELAATVTGITDDLDKFSLI-----------------CQRSTSEPDDTSDFNFLQGL--SL 429

  Fly  1735 K---------CFSKLT----NACLRLMNVLMEYFLDYLLEPAFARLLWYCRNA--ITVDELLVAN 1784
            |         .||..|    |...|.:.::..|  .|.::..:|:..|..::|  :..:..::..
  Fly   430 KYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTY--QYEIQRVWAKQTWRAKSAKDVPPNNKIITL 492

  Fly  1785 RKYLK-------------------TIILGSLQTKNLRKYLERLYDLILQLDNKHWKFLRLCQTSV 1830
            |.||.                   .|::..:::::..:.::|.:.:.|.....|...|...:|.:
  Fly   493 RNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQL 557

  Fly  1831 EYVIRVRKEKPQSIFSTYYR--------ERMLQFRWTCQNYSDVINEMKDQFDLAMISFLLCLHL 1887
            . |...:...|  |:.|..:        ..|.|.:....:..|.::::.:.|.:.:.|.:..  |
  Fly   558 N-VTGSQNRNP--IYGTLLKLFGICEKFAHMTQTKDPSDDLEDEVDQLNESFGVQIASLIQL--L 617

  Fly  1888 ADDDS------LRSLAKRLDPEHYYMEKDN 1911
            .|..|      |..|..|||...::....|
  Fly   618 VDVKSASCLGPLSQLLLRLDFNCWFSASHN 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip91	NP_723933.1	GCP_N_terminal	1312..1591	CDD:465456	59/309 (19%)
		GCP_C_terminal	<1690..1906	CDD:461187	42/263 (16%)
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	75/383 (20%)
		GCP_C_terminal	349..642	CDD:461187	56/345 (16%)