Protein Alignment Ku80 and KU80

DIOPT Version :10

• Sequence 1: NP_609767.2
• Gene: Ku80 / 34930
• FlyBaseID: FBgn0041627
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_564520.1
• Gene: KU80 / 841223
• AraportID: AT1G48050
• Length: 680
• Species: Arabidopsis thaliana
• Alignment Length: 739
• Identity: 151/739 - (20%)
• Similarity: 295/739 - (39%)
• Gaps: 130/739 - (17%)

  Fly     1 MASNKECLIIVLDVRTCAAEEVKLKSAKCVAEILKDKIVCDRKDYVSFVLVGCDT--DEIKTEDA 63
            ||.|:|.|::||||.. |...|.....|..:.:|:.|::.::.|.|..|:.|.:.  :|:..|..
plant     1 MARNREGLVLVLDVGP-AMRSVLPDVEKACSMLLQKKLIYNKYDEVGIVVFGTEETGNELAREIG 64

  Fly    64 SHPNVLPFGEPRLCSWQLLLEFFQFVNKTACED----------GEWLNGLQAALE-LQNVATTLR 117
            .:.||            .:|...:.|::.|.|.          |::|:.|...:: |..:.....
plant    65 GYENV------------TVLRNIRVVDELAAEHVKQLPRGTVAGDFLDALIVGMDMLIKMYGNAH 117

  Fly   118 VARRRILLLFD--------FNDFPQDYEKFNEITDELLGENI--ELIVGTHNIA--YIDNAITSQ 170
            ..::|:.|:.:        |.....|  :.:.|..::..|.|  |.||...|::  ..:..|...
plant   118 KGKKRMCLITNAACPTKDPFEGTKDD--QVSTIAMKMAAEGIKMESIVMRSNLSGDAHERVIEEN 180

  Fly   171 PQAIFNFSRKCGPDELNNQKYALSLVPRCNATLCSFKEALHTVFKVTNRRPWVWNAKLNIGSKIS 235
            ...:..||.......:|... .|||:    .:|.:.:.|..|:|:        .:.::|...||.
plant   181 DHLLTLFSSNAIAKTVNVDS-PLSLL----GSLKTRRVAPVTLFR--------GDLEINPTMKIK 232

  Fly   236 ISLQGIIAMKNQTPVKLVKVWAEKDEIVIRETRHYIK----------GTEITPLPENLITGYMLG 290
            :.:...:| :.:.|.  :|::::|.....:..:|.:|          .||:. .||..|.|:..|
plant   233 VWVYKKVA-EERLPT--LKMYSDKAPPTDKFAKHEVKVDYDYKVTAESTEVI-APEERIKGFRYG 293

  Fly   291 GTPVPYDEAVLEP-KEPHPPGLHFFGFIKRNAVPDEYFCGESLYLLVHQKHNQSAAVKLDALVRA 354
            ...:|.....:|. |.....|:...||.:.:.:...|:. :.:.::|.....:.:.:.:.|:.|.
plant   294 PQVIPISPDQIETLKFKTDKGMKLLGFTEASNILRHYYM-KDVNIVVPDPSKEKSVLAVSAIARE 357

  Fly   355 LVSSDRAILCWKIYSTKFNRPQMVVLLPRLA--DDTHPATLYMLEVSYTSQHHFWDFPALRTTKT 417
            :..:::..:...::........:.||.|.::  ||| |.:.|...:.:......:.||:.....:
plant   358 MKETNKVAIVRCVWRNGQGNVVVGVLTPNVSERDDT-PDSFYFNVLPFAEDVREFPFPSFNKLPS 421

  Fly   418 ECS-EEQLNAI-DQLIDSTDLECTLRDTQQPRPWAQNDLLPFDALPSIFEQNVMDILERKVIYDN 480
            ... :||..|: |.|:...||          .|.|:.::|..|..|:...|...:.||.|    :
plant   422 SWKPDEQQQAVADNLVKMLDL----------APSAEEEVLKPDLTPNPVLQRFYEYLELK----S 472

  Fly   481 DKEDKML--KDKNFADVFWRVPDPLEEKSK------RAAAIVKKLFPLRYS--RAWQEKLLAKEQ 535
            ...|..|  .|..|..:..:.|: |...:|      |.:..||:...|:.:  |..::|....:.
plant   473 KSTDATLPPMDGTFKRLMEQDPE-LSSNNKSIMDTFRGSFEVKENPKLKKASKRLLRDKPSGSDD 536

  Fly   536 AENGVAVKSEPAEKEIPLPSDGVGLIDPISDFRRVLASVHTISNATERDARFQALAADTRVVIIT 600
            .:|.: :..:..|.:|    |.||..:||.||..:      ||...:.|...:|: ...:.:|:.
plant   537 EDNRM-ITYDAKENKI----DIVGDANPIQDFEAM------ISRRDKTDWTEKAI-TQMKNLIMK 589

  Fly   601 LLQRRKQNIGQLGELITLYRQSCI------DFNTFLEY-DKFAEE-----------LKKIALAKN 647
            |::.......:..|.:...|:.|:      .||.||.: .|..:|           .|||.|..
plant   590 LVENCTDEGDKALECVLALRKGCVLEQEPKQFNEFLNHLFKLCQERNLSHLLEHFMSKKITLIP- 653

  Fly   648 RSEFWQDVMVDKQLGPLVLGEPTL 671
            :||.....:||:..|..::.:.::
plant   654 KSEAADSDIVDENAGDFIVKQESM 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:427470	46/230 (20%)
		KU80	221..524	CDD:238445	63/327 (19%)
		Ku_PK_bind	562..>659	CDD:462604	26/114 (23%)
KU80	NP_564520.1	vWFA	5..238	CDD:469594	52/260 (20%)
		KU80	216..517	CDD:238445	64/329 (19%)
		Ku_PK_bind	558..672	CDD:462604	28/121 (23%)