DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ku80 and RLBP1

DIOPT Version :9

Sequence 1:NP_609767.2 Gene:Ku80 / 34930 FlyBaseID:FBgn0041627 Length:699 Species:Drosophila melanogaster
Sequence 2:XP_016877949.1 Gene:RLBP1 / 6017 HGNCID:10024 Length:326 Species:Homo sapiens


Alignment Length:251 Identity:47/251 - (18%)
Similarity:81/251 - (32%) Gaps:100/251 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   454 LLPFDALPSIF------EQNVMDILERKVIYDNDKEDKMLKDKNFADVF-----------WRVPD 501
            |.||.|....|      ||.:...||:            |..|:...||           .:..|
Human     7 LFPFSAQVGTFRMVPEEEQELRAQLEQ------------LTTKDHGPVFGPCSQLPRHTLQKAKD 59

  Fly   502 PLEEKSKRAAAIVKKLFPLRYSRAWQEKLLAKEQAENGVAVKSEPAEKEIPLPSDGVGLIDPISD 566
            .|.|:.:.....|::|         ||  :.:.||.:|..:....||:                 
Human    60 ELNEREETREEAVREL---------QE--MVQAQAASGEELAVAVAER----------------- 96

  Fly   567 FRRVLASVHTISNATERDARFQALAADTRVVIITLLQRRKQNIGQLGELITLYRQSCIDFNTFLE 631
                         ..|:|:.|          .:..::.||.|:|:..||:..|    ::|.  |:
Human    97 -------------VQEKDSGF----------FLRFIRARKFNVGRAYELLRGY----VNFR--LQ 132

  Fly   632 YDKFAEELKKIALAKNRSEFWQDVMVDK-QLGPLVLGEPTLDDELALKAYYTIENW 686
            |.:..:.|...|:.......:..|:..: :.|.:|:             .:.||||
Human   133 YPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVM-------------LFNIENW 175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ku80NP_609767.2 Ku_N 7..213 CDD:281693
KU80 221..524 CDD:238445 18/86 (21%)
Ku_PK_bind 562..663 CDD:285938 16/101 (16%)
RLBP1XP_016877949.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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