Protein Alignment Ku80 and Ttpa

DIOPT Version :9

• Sequence 1: NP_609767.2
• Gene: Ku80 / 34930
• FlyBaseID: FBgn0041627
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_056582.1
• Gene: Ttpa / 50500
• MGIID: 1354168
• Length: 278
• Species: Mus musculus
• Alignment Length: 196
• Identity: 41/196 - (20%)
• Similarity: 60/196 - (30%)
• Gaps: 71/196 - (36%)

  Fly   498 RVPDPLEEKSKRAAAIVKKLFPLRYSRAWQEKL-LAKEQAENGVAVKSEPAEKEIPL-PSDGVGL 560
            :.|.||.:           .|.||:.||....| ||....:|....::|..|....| |...:||
Mouse    42 QTPQPLTD-----------AFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLRPRSILGL 95

  Fly   561 IDPISDFRRVLASVHTISNATERDARFQALAADTRVVIITLLQRRKQNIGQLGELITLYRQSCID 625
            :.  :.:..||.|         ||:                          .|..:.:||.:..|
Mouse    96 LK--AGYHGVLRS---------RDS--------------------------TGSRVLIYRIAYWD 123

  Fly   626 FNTFLEYDKFAEELKKIALAKNRSEFWQDVMVDKQLGPLVLGEPTLDDELALKAYYTIENWVESG 690
            ...|..||.|...|....|      ..|:|...:.               .:||.:.:|.|..|.
Mouse   124 PKVFTAYDVFRVSLITSEL------IVQEVETQRN---------------GVKAIFDLEGWQVSH 167

  Fly   691 A 691
            |
Mouse   168 A 168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	6/25 (24%)
		Ku_PK_bind	562..663	CDD:285938	17/100 (17%)
Ttpa	NP_056582.1	CRAL_TRIO_N	25..73	CDD:215024	11/41 (27%)
		CRAL_TRIO	99..248	CDD:279044	23/126 (18%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W67	190..192
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W68	208..211

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900