Protein Alignment Ku80 and Sec14l4

DIOPT Version :9

• Sequence 1: NP_609767.2
• Gene: Ku80 / 34930
• FlyBaseID: FBgn0041627
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001102560.1
• Gene: Sec14l4 / 498399
• RGDID: 1565810
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 97/479 - (20%)
• Similarity: 149/479 - (31%)
• Gaps: 159/479 - (33%)

  Fly   195 LVPRCNATLCSFKEALHTVFKVTNRRP------WVWNAKLNIGSKISISLQGIIAMKNQTPVKLV 253
            |.|:....|..|:|.|..|.....:..      |:.....:: .|....|:..:..:||..:..:
  Rat     8 LSPQQQEALTRFREILQDVLPTLPKADDFFLLRWLRARNFDL-KKSEDMLRKHVEFRNQQDLDHI 71

  Fly   254 KVWAEKDEIVIRETRHYIKGTEITPLPENLITGYMLGGTPVPYD-EAVLEPKEPHPPGLHFFGFI 317
            ..| :..|::    |.|..|.         :.||...|.||.:| ...|:||     || |....
  Rat    72 LTW-QPPEVI----RLYDSGG---------LCGYDYEGCPVWFDLIGTLDPK-----GL-FMSAS 116

  Fly   318 KRNAVPDEYFCGESLYLLVHQKHNQSAAV--KLDALVRALVSSDRAIL-CWK----IYSTKF--- 372
            |::.:.......|   :|:|:...||..:  |::.:|........::. .||    :|...|
  Rat   117 KQDLIRKRIKVCE---MLLHECELQSQKLGRKVERMVMVFDMEGLSLRHLWKPAVEVYQQFFAIL 178

  Fly   373 --NRPQ-----MVVLLPRLADDTHPATLYMLEVSYTSQHHFWDFP-ALRTTKTECSEEQLNAIDQ 429
              |.|:     :|:..|:|                        || |....|:...|.....|..
  Rat   179 EANYPETVKNLIVIRAPKL------------------------FPVAFNLVKSFIGEVTQKKIVI 219

  Fly   430 LIDSTDLECTLRDTQQPRPWAQNDLLPF---DALPSIFEQNVMDILERKVIYDNDKEDKMLKDKN 491
            |..:               |.| :||.|   |.||..|...:.         |.|...|.|...|
  Rat   220 LGGN---------------WKQ-ELLKFMSPDQLPVEFGGTMT---------DPDGNPKCLTKIN 259

  Fly   492 F-ADVFWRVPDPLEEKSKRAAAIVKKLFPLRYSRAWQEKLLAKEQAENGVAV---KSEPAEKEIP 552
            : .||                       |..|..:.||    :.|.|:.|.|   .|...|.||.
  Rat   260 YGGDV-----------------------PKHYHLSSQE----RPQYEHNVVVGRGSSHQVENEIL 297

  Fly   553 LP---------SDG------------VGLIDPISDFRRVLASVHTISNATERDARFQALAADTRV 596
            .|         |||            :|......:...||.:....|:....|.....|.....|
  Rat   298 FPGCVLRWQFASDGGDIGFGIFLKTRMGERQKAGEMTEVLPNQRYNSHMVPEDGSLTCLKTGVYV 362

  Fly   597 V----IITLLQRRKQNIGQLGELI 616
            :    ..:||..:|  :|...|::
  Rat   363 LRFDNTYSLLHTKK--VGYTAEVL 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	6/17 (35%)
		KU80	221..524	CDD:238445	64/331 (19%)
		Ku_PK_bind	562..663	CDD:285938	11/59 (19%)
Sec14l4	NP_001102560.1	CRAL_TRIO_N	13..59	CDD:215024	8/46 (17%)
		SEC14	76..244	CDD:214706	49/229 (21%)
		GOLD_2	284..379	CDD:404736	19/96 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900