DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ku80 and CG33966

DIOPT Version :9

Sequence 1:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001033984.1	Gene:	CG33966 / 3885642	FlyBaseID:	FBgn0053966	Length:	310	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	58/294 - (19%)
Similarity:	105/294 - (35%)	Gaps:	86/294 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 PALRTTKTECSE---EQLNAIDQLIDSTDLECTLRD--TQQPRPWAQNDLLPFDALPSIFEQNVM 469
            ||:|....|..:   |.||.:...:|  |....|||  .|||...|:.|    |.....|.:...
  Fly     2 PAIRPLSPELQKTAIENLNEVPNKLD--DDIAALRDWIKQQPHLKARTD----DQFLVNFLRGCK 60

  Fly   470 DILER---KV--------------IYDNDKEDKMLKDKNFADVFWRVPDPLEEKSKRAAAIVKKL 517
            ..|||   |:              :..|...||.|:......:. .:|.||.:...|.|.:....
  Fly    61 FSLERTKSKIDRFYTLRTKYPEFYLGHNVDVDKALEIFRLGTIV-ILPRPLNDNGPRLALLRMAC 124

  Fly   518 F-PLRY-----SRA---WQEKLLAKEQAE--NGVA-------------VKSEPA---------EK 549
            : |.:|     :||   .|:.:|.::...  ||:.             ::..|:         |:
  Fly   125 YDPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHFLQMSPSFAKKMTVFQEE 189

  Fly   550 EIPLPSDGVGLIDPISDFRRVLASVHTISNATER------DARFQALAADTRVVIITLLQRRKQN 608
            .:||...|:..|:..:.|..:...:..:.:..::      .::::||          ..|..||.
  Fly   190 ALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKWEAL----------YNQIPKQY 244

  Fly   609 I--------GQLGELITLYRQSCIDFNTFLEYDK 634
            :        |.:.||:..:.|..:.:..:.|.:|
  Fly   245 LPVEYGGENGSIPELLQQWEQRILAYRNYWEEEK 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	34/141 (24%)
		Ku_PK_bind	562..663	CDD:285938	12/87 (14%)
CG33966	NP_001033984.1	CRAL_TRIO_N	30..72	CDD:215024	14/45 (31%)
CG33966	NP_001033984.1	SEC14	96..252	CDD:238099	25/166 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900