DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ku80 and CG10026

DIOPT Version :9

Sequence 1:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	64/318 - (20%)
Similarity:	112/318 - (35%)	Gaps:	111/318 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VRTCAAEEVKLKSAKCVAEILKDKIVCDRKDYVSFVLVGCDTDEIKTEDASHPNVLPFGEPRLC- 77
            :|..|.|:.:..|:       |||::...::|:      .:.:|.:...:....:..|...|..
  Fly    28 IRRLAQEQGECPSS-------KDKVIEQFRNYI------LEHNECQPHRSDAKYLEKFLRARYWK 79

  Fly    78 ---SWQLLLEFFQF--VNKTACEDGEWLNGLQAALELQNV-------ATTLRVARRRILLLFDFN 130
               |::||..:::|  .||:..|.       ...|:|::|       .|..|......:|::.|.
  Fly    80 IENSYKLLCSYYRFREQNKSFYEK-------VRPLDLRHVGQSDILTVTPYRDQHGHRILIYRFG 137

  Fly   131 DFPQDYEKFNEIT-DEL---------LG--ENIELIVGTHNI-----AYIDNAITSQPQAIFNFS 178
            .:     :.|::| |::         ||  |.|..|||...|     ..:::.:...|...
  Fly   138 LW-----RPNQVTVDDIFRATIVLQELGSLEPISQIVGGVGIFDLKDLGLEHILHLSPSVA---- 193

  Fly   179 RKCGPDELNNQKYALSLVPRCNATLCSFKEALHTVFKVTNRRPWVWNAKLNIGSKISISLQGIIA 243
                      ||....||    .::.....|||.|     .:.||:||..
  Fly   194 ----------QKMIALLV----TSMPIRTSALHIV-----NQNWVFNAAF--------------- 224

  Fly   244 MKNQTPVKLVKVWAEKDEIVIRETRHYIKGTEITPL-----PENLITGYMLGGTPVPY 296
                      |::.......:|| :.||.|:::|.|     ||:|...|  ||....|
  Fly   225 ----------KIFKPFLNAAMRE-KLYIHGSDMTSLHKHINPEHLPKRY--GGLHEDY 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	44/228 (19%)
		KU80	221..524	CDD:238445	19/81 (23%)
		Ku_PK_bind	562..663	CDD:285938
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	9/52 (17%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	42/208 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900