DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ku80 and CG5973

DIOPT Version :9

Sequence 1:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001162901.1	Gene:	CG5973 / 34023	FlyBaseID:	FBgn0031914	Length:	311	Species:	Drosophila melanogaster

Alignment Length:	220	Identity:	43/220 - (19%)
Similarity:	87/220 - (39%)	Gaps:	58/220 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   416 KTEC---SEEQLNAIDQLIDSTDLECTLRDTQQPRPW----AQNDLLPFDALPSIFEQNVMDILE 473
            |.||   .|.:|..||  :.|..:.   .:.:|...|    ||::|   ..:|.:.||.:.::.|
  Fly     3 KAECISYDEHKLPYID--LGSAQIR---MEKEQAPEWALKKAQDEL---REVPGVKEQAIKELRE 59

  Fly   474 RKVIYDNDKEDKMLKDKNFADVFWR----VPDPLEEKSK-------RAAAIVKKLFPLRYSRAWQ 527
               :..|:|...:..|..:..:|.|    .|:...::.|       :..|..:.:.|.:....::
  Fly    60 ---LIQNEKYLNLPLDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENIIPSKLRNVFE 121

  Fly   528 EKL--LAKEQAENG-------VAVKSEPAEKEIPLPS--DGV------GLIDPISDFRRVLASVH 575
            ..:  |..::.::|       ...|.:|:  ::||..  .|:      .:::|.|   ::..||.
  Fly   122 ANILNLLPQRDQHGRRLLVLEAGKKWKPS--QVPLVDLFRGIQLTVLGSMVEPYS---QICGSVV 181

  Fly   576 TI-------SNATERDARFQALAAD 593
            .|       |:.|:....|.|:..|
  Fly   182 IIDMEGLPLSHITQFTPSFAAMLLD 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	26/125 (21%)
		Ku_PK_bind	562..663	CDD:285938	10/39 (26%)
CG5973	NP_001162901.1	CRAL_TRIO_N	51..96	CDD:215024	9/47 (19%)
CG5973	NP_001162901.1	SEC14	116..272	CDD:238099	17/96 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900