Protein Alignment Ku80 and Sec14l5

DIOPT Version :9

• Sequence 1: NP_609767.2
• Gene: Ku80 / 34930
• FlyBaseID: FBgn0041627
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001129182.2
• Gene: Sec14l5 / 287060
• RGDID: 1564638
• Length: 696
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 86/405 - (21%)
• Similarity: 133/405 - (32%)
• Gaps: 133/405 - (32%)

  Fly    67 NVLPFGEPRLCSWQLLLEFFQFVNKTACEDGEWLNGLQAALEL-----QNVATTLRVARRRILLL 126
            |...||.| :.||..||: .:.:|....    |..|::|.|.:     .|...||    .|:|::
  Rat   368 NTRQFGRP-ISSWTCLLD-LEGLNMRHL----WRPGVKALLRMIEVVEDNYPETL----GRLLIV 422

  Fly   127 FDFNDFPQDYEKFNEITDELLGENIE---LIVGTHN-------IAYIDNAITSQPQAIFNFSRKC 181
                ..|:.:.....:....:.||..   ||....|       :.|:|..:.
  Rat   423 ----RAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVI------------- 470

  Fly   182 GPDELNNQKYALSLVPRCNATLCSFKEALHTVFKVTNRRPWVWNAKLNIGSKISISLQGIIAMKN 246
             ||.|..:            ::|:..|                      |..:..||  .:..:.
  Rat   471 -PDFLGGE------------SVCNVPE----------------------GGMVPKSL--YLTEEE 498

  Fly   247 QTPVKLVKVWAE--KDEIVIRETRHYIKGTEITPLPENLIT---GYMLGGTPVPYDEAVLEPK-E 305
            |.....::.|:|  ....|:|.:.|.: ..|| |..|::||   ..:.|........|...|| .
  Rat   499 QEQADQLRQWSETYHSASVLRGSPHEV-AMEI-PEGESVITWDFDILRGDVVFSLYHAKQAPKLS 561

  Fly   306 PHPPGLHFFG-FIKRN--------AVPDEYFC--GESL-----------YLLVHQKHN--QSAAV 346
            |..||:...| .|.:|        .|.....|  |:|:           |||..|.|:  :|.|.
  Rat   562 PQEPGVRASGQLIDKNWILGVDYSRVEAPLICREGQSIQGSHVTQWPGVYLLQWQIHSPPESVAC 626

  Fly   347 KL---DALVRALVSSDRAILCWKIYSTKFNRPQMVVLLPRLADDTHPATLYMLEVSYTSQHHFWD 408
            .|   |.::.||.|....  |..:|..:.           ||.:....::..|| |..|:
  Rat   627 SLPGVDDVLTALHSPGPK--CKLLYYCEV-----------LASEDFRGSMSSLE-SCASR----- 672

  Fly   409 FPALRTTKTECSEEQ 423
            |..|..|.|..|..|
  Rat   673 FSQLSATTTSSSSGQ 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	31/160 (19%)
		KU80	221..524	CDD:238445	55/236 (23%)
		Ku_PK_bind	562..663	CDD:285938
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489
		CRAL_TRIO_N	243..288	CDD:215024
		CRAL_TRIO	314..477	CDD:306996	29/136 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900