Protein Alignment Ku80 and Sec14l4

DIOPT Version :9

• Sequence 1: NP_609767.2
• Gene: Ku80 / 34930
• FlyBaseID: FBgn0041627
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_666125.1
• Gene: Sec14l4 / 103655
• MGIID: 2144095
• Length: 403
• Species: Mus musculus
• Alignment Length: 477
• Identity: 97/477 - (20%)
• Similarity: 150/477 - (31%)
• Gaps: 155/477 - (32%)

  Fly   195 LVPRCNATLCSFKEALH----TVFKVTNRRPWVWNAKLNIGSKISIS-LQGIIAMKNQTPVKLVK 254
            |.|:....|..|:|.|.    |:.|..:.....|....|...|.|.. |:..:..:||..:..:.
Mouse     8 LSPQQQEALARFRETLQDLLPTLPKADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQNLDQIL 72

  Fly   255 VWAEKDEIVIRETRHYIKGTEITPLPENLITGYMLGGTPVPYD-EAVLEPKEPHPPGLHFFGFIK 318
            .|...:.|.:     |..|.         ::||...|.||.:| ...::||     || |....|
Mouse    73 TWQAPEVIQL-----YDSGG---------LSGYDYEGCPVWFDIIGTMDPK-----GL-FMSASK 117

  Fly   319 RNAVPDEYFCGESLYLLVHQKHNQSAAV--KLDALVRALVSSDRAIL-CWK----IYSTKF---- 372
            ::.:.......|   :|:|:...||..:  |::.:|........::. .||    :|...|
Mouse   118 QDMIRKRIKVCE---MLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILE 179

  Fly   373 -NRPQ-----MVVLLPRLADDTHPATLYMLEVSYTSQHHFWDFP-ALRTTKTECSEEQLNAIDQL 430
             |.|:     :::..|:|                        || |....|:...||....|..|
Mouse   180 ANYPETVKNLIIIRAPKL------------------------FPVAFNLVKSFMGEETQKKIVIL 220

  Fly   431 IDSTDLECTLRDTQQPRPWAQNDLLPF---DALPSIFEQNVMDILERKVIYDNDKEDKMLKDKNF 492
            ..:               |.| :|:.|   |.||..|...:.         |.|...|.|...|:
Mouse   221 GGN---------------WKQ-ELVKFVSPDQLPVEFGGTMT---------DPDGNPKCLTKINY 260

  Fly   493 ADVFWRVPDPLEEKSKRAAAIVKKLFPLRYSRAWQEKLLAKEQAENGVAV---KSEPAEKEIPLP 554
            ...                      .|.||..:.||    :.|.|:.|.|   .|...|.||..|
Mouse   261 GGE----------------------VPKRYYLSNQE----RPQYEHSVVVGRGSSHQVENEILFP 299

  Fly   555 ---------SDG------------VGLIDPISDFRRVLASVHTISNATERDARFQALAADTRVV- 597
                     |||            :|......:...||.|....::....|.....|.|...|:
Mouse   300 GCVLRWQFASDGGDIGFGVFLKTRMGERQKAGEMVEVLPSQRYNAHMVPEDGSLNCLKAGVYVLR 364

  Fly   598 ---IITLLQRRKQNIGQLGELI 616
               ..:||..:|  :|...|::
Mouse   365 FDNTYSLLHTKK--VGYTAEVL 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	6/21 (29%)
		KU80	221..524	CDD:238445	62/325 (19%)
		Ku_PK_bind	562..663	CDD:285938	12/59 (20%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	11/45 (24%)
		SEC14	77..244	CDD:214706	46/229 (20%)
		GOLD_2	284..379	CDD:290608	20/96 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900