Protein Alignment Gli and cel.2

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001020344.2
• Gene: cel.2 / 565117
• ZFINID: ZDB-GENE-061110-10
• Length: 551
• Species: Danio rerio
• Alignment Length: 605
• Identity: 172/605 - (28%)
• Similarity: 269/605 - (44%)
• Gaps: 120/605 - (19%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201
            |.|..|.|||           ||     ||.  .::....||.|||:|.||   ||.:.|..|.|
Zfish    26 VLTEGGMVQG-----------KS-----HSV--GLLRYMDVFKGIPFAAPP---GRLQKPVPHPG 69

  Fly   202 WQ-LLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIR 265
            |: :|:|.::...|.|.......|.|    .|||||||::.|: |..|:...||||:|:||.|:.
Zfish    70 WEGVLKATEYSKRCIQLNLLQTDTMG----SEDCLYLNIWVPQ-GKTVSYNLPVMVFIYGGGFLL 129

  Fly   266 GASN--------LFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYD 322
            |...        |:.|..:|...:|:|||.|||:|::|||||||.::|||||:.||..|:.||:.
Zfish   130 GGGQGANFLDNYLYDGEEIADRGNVIVVTFNYRVGSMGFLSTGDADAPGNYGLWDQHAAISWVHR 194

  Fly   323 NIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQD--KYRAQNT 385
            ||:.|.|:.::||:||..||..|....:::|:.:.::||.|:|||.||..||:.::  |:..:..
Zfish   195 NIKAFGGNPDNITIFGESAGSTSVNFQIISPKNKGLIRRAISQSGVALCPWAINRNPRKFAEEIA 259

  Fly   386 SRVLGQLLGCSIESSWKLVNCLR-------TGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGD 443
            .:|     ||..:|.  :|.|||       |......|..:...|.|.:....||:|      ||
Zfish   260 KKV-----GCPTDSG--MVACLRRTDPKAVTLAGKVRLATSATEPIVHNLYLSPVID------GD 311

  Fly   444 DWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFV-----AQNESLSPYYELDG 503
                        |:...|:||....   .:|.|:.||...:...|.     :.|.:|:...|.:.
Zfish   312 ------------FIPDEPDTLFGNA---ADIDYIAGVNDMDGHIFATLDIPSINNALATTTEEEV 361

  Fly   504 RFFDQKIREH--------VFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINMLSDLYYR 560
            :.....:.:.        .|: .||:|              |....|...|:...:.|.:|..:.
Zfish   362 QALATALSKDRGQDAGIATFQ-EYTVN--------------WGSKPNKEDIKKTVVEMETDYIFL 411

  Fly   561 APVDQMVKLMLE--QKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPF-MDTEFFPKKEH 622
            .|....:.|..:  :....|.|:.:.:......|.|....|..|..::.|.|| ....:||:
Zfish   412 VPTQTALYLHSDNAKSARTYSYLFSESSRIPIFPLWMGADHADELQYVFGKPFTTPLGYFPR--- 473

  Fly   623 LQRNMWTDNDRNMSHFFMQTYTNFARYGNP-TPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLN 686
                     .|::|.:.:..:||||:.||| |.:..:.:.:........:||:||...|::.:..
Zfish   474 ---------HRDVSKYMIAYWTNFAQTGNPNTGESKVPVTWPEFSNPGHQYLDINNKINTNSVKK 529

  Fly   687 YRQTECA-FWTQYL---PTV 702
            ..:|... :||...   |||
Zfish   530 MLRTRLVYYWTTVFASYPTV 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	167/593 (28%)
cel.2	NP_001020344.2	COesterase	26..539	CDD:306613	167/593 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870