Protein Alignment Gli and Ace

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001163600.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 641
• Identity: 154/641 - (24%)
• Similarity: 253/641 - (39%)
• Gaps: 152/641 - (23%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMG-ECSVFLGIPYALPPTFEGRFKPPRVHR 200
            |.|:.|.|:|..|                    .|.| |..|:.|||||.||..:.||:.|....
  Fly    45 VQTSSGPVRGRSV--------------------TVQGREVHVYTGIPYAKPPVEDLRFRKPVPAE 89

  Fly   201 GWQ-LLQAVDFGPACPQP-VRYTGATKG------IMDMDEDCLYLNVYSP-----KTGAG----- 247
            .|. :|.|......|.|. ..|.....|      ..::.|||||:||::|     :.|.|
  Fly    90 PWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGE 154

  Fly   248 --------------------VAQKYPVMVYIHGGEFIRGASNL--FQGHILASFYDVVVVTLNYR 290
                                .....|::::|:||.|:.|::.|  :...|:|:..:|:|.:..||
  Fly   155 HPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYR 219

  Fly   291 LGALGFL-------STGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGL 348
            :||.|||       |...|.:|||.|:.|||:|:||:.||...|.|:...:||||..||.:|...
  Fly   220 VGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNA 284

  Fly   349 LMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLL--GCSIESSW------KLVN 405
            .:::|.||.:|:|.:.|||:..|.|:.:..:...:     :|:.|  .|:..:|.      .:::
  Fly   285 QLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVE-----IGKALINDCNCNASMLKTNPAHVMS 344

  Fly   406 CLRTGRSFYELGNAEFSPQ-------VGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPET 463
            |:|:      :.....|.|       :.|||..|.:|..| ||.|                 |.|
  Fly   345 CMRS------VDAKTISVQQWNSYSGILSFPSAPTIDGAF-LPAD-----------------PMT 385

  Fly   464 LIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVY- 527
            |::.... ::...:.|....|..:|:.       |..:|  :||:.....:.|..|....|.::
  Fly   386 LMKTADL-KDYDILMGNVRDEGTYFLL-------YDFID--YFDKDDATALPRDKYLEIMNNIFG 440

  Fly   528 -------EAIKYIYTFW---PDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVL 582
                   |||.:.||.|   |...|    :.|....:.|.::..|.::..:.:.|:...|:.|..
  Fly   441 KATQAEREAIIFQYTSWEGNPGYQN----QQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYF 501

  Fly   583 NTTVEALNLPQWRKYPHDIERYFLTGAPFMDT-EFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNF 646
            ..........:|....|..|..:..|.|..:: ::.|.:..|.:.|            :.....|
  Fly   502 THRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRM------------LSAVIEF 554

  Fly   647 ARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTV 702
            |:.|||........:|.:  :..:.|:.........:........|:||..|||.|
  Fly   555 AKTGNPAQDGEEWPNFSK--EDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKV 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	148/632 (23%)
Ace	NP_001163600.1	COesterase	41..601	CDD:278561	148/632 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840