Protein Alignment Gli and CG4757

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 170/639 - (26%)
• Similarity: 254/639 - (39%)
• Gaps: 179/639 - (28%)

  Fly   129 LTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRF 193
            |::|    |.|..|:|:|..:                  ..|:......|.||.||.||..:.||
  Fly    19 LSIE----VDTELGRVRGANL------------------TSRLGVNFHAFRGIRYAEPPLGDLRF 61

  Fly   194 KPPRVHRGW--QLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMV 256
            ..|:..:.|  ::..|.:.||.||||      ...:.|:.||||.||||:    ..:..:.||:|
  Fly    62 VNPQPVKPWSPKIFDASEDGPMCPQP------WDNMTDVSEDCLRLNVYT----KDLKGRRPVIV 116

  Fly   257 YIHGGEF--IRGASNLFQG--HILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMAL 317
            ::|.|.|  ..|.|....|  |.:..  |.|:|:||||||:||||:||.:.:|||.|:.||.:||
  Fly   117 FLHPGGFYVFSGQSKYLAGPEHFMDR--DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLAL 179

  Fly   318 RWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYR- 381
            ||:..:|:.|.||.:|:||.|..||..|..|.|::|.:|.:..|.|..|.   |.:..:  ||:
  Fly   180 RWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA---APYGPV--KYKD 239

  Fly   382 --AQNTSRVLGQLLGCSIESSWKLVNCLR---------TGRSFYELGNAEFSPQVGSFPWGPVLD 435
              .|...|..| ||.|..||..::|.|:|         |....:|.|            |.|||:
  Fly   240 NDLQLAKRQAG-LLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFG------------WNPVLN 291

  Fly   436 HNFTLPGDDWYEGWR---EKDW---RFLTQTPETLIRAGKFNRNIQYMTGVTTQE---AAFFVAQ 491
                         ||   |||:   |:|.::|....|.|.|:: :..:||:|..|   .|||..:
  Fly   292 -------------WRIVVEKDFGQERYLIESPFKTARRGDFHK-VALITGITEFEFLSGAFFDLR 342

  Fly   492 NESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYI----- 551
            |||:...|..|.        ||.......|..|.......           :.:.|::|:
  Fly   343 NESIVNRYNRDW--------EHYASIALLLEQNSTQSRAA-----------SRVFREKYMPESLD 388

  Fly   552 ------------NMLSDLYYRAPVDQMVKLMLEQKVPVYMYVL--------------NTTVEALN 590
                        .:|||........:.::|| ....|:|.|:.              ..|:..::
  Fly   389 KLEYPKSLKGMGELLSDALIGVSFHRFLQLM-SPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVH 452

  Fly   591 LPQWRKYPHDIERY-FLTG--APFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNP 652
                    ||...| |..|  .|.:..|              |.:..|.....:.:..||:.|:|
  Fly   453 --------HDELIYLFHVGLLIPLLKRE--------------DPENFMIELLTRMWIEFAQKGDP 495

  Fly   653 ---TPQQVLGMHFQRAYQGEIRYLNIN---TTYNSSILLNYRQTECAFWTQYLP 700
               ..:.:.|:::......:..||.|.   |..:....||..|    .|....|
  Fly   496 HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQ----IWEDLFP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	166/627 (26%)
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	168/632 (27%)
		Aes	40..>204	CDD:223730	70/175 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440421
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740