Protein Alignment Gli and alpha-Est1

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 159/582 - (27%)
• Similarity: 234/582 - (40%)
• Gaps: 151/582 - (25%)

  Fly   137 VTTNYGQVQGFK---VYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRV 198
            |.|..|||:|.:   :|     |.:.::               .|.|||:|.||..|.||:.|:.
  Fly    35 VCTRDGQVRGHRRRTLY-----DEEMYF---------------AFEGIPFAQPPVGELRFRAPQP 79

  Fly   199 HRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEF 263
            ...|..::...:..|.|....:   ...|::..||||||||||.:..:.  :..||:|:|:||.|
  Fly    80 PHPWLGVRDCTYPRAKPMQKHF---VLSIVEGSEDCLYLNVYSKRLRSD--KPLPVIVWIYGGGF 139

  Fly   264 IRGASNLFQGHILASFY--------DVVVVTLNYRLGALGFLSTGDE--NSPGNYGILDQAMALR 318
            ..|.:.       ..||        ||||||.|||:|||||||..|.  :.|||.|:.||.||||
  Fly   140 QFGEAG-------RDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALR 197

  Fly   319 WVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQ 383
            |:..||..||||..:||:.|..||.||...||...|||.:..:.|.||||...:||   ::...:
  Fly   198 WISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWA---NEPSGR 259

  Fly   384 NTSRVLGQLLGCSIESSWKLVNCLRTGRSF------YELGNAEFSPQVGSFPWGPVLD------- 435
            ...|:..||.....|:..::...|:...:.      ..|.:.|...|...||:.||::
  Fly   260 WAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDC 324

  Fly   436 -----HNFTLPGDDWYEGWREKDWRFLTQTPETLIRAG-KFNRNIQYMTGVTTQE---AAFFV-- 489
                 |...||     |.|.       ...|  ||..| .|.....|.:.:..:|   :||.|
  Fly   325 VLPRCHREMLP-----EAWG-------NDLP--LILGGNSFEGLFSYQSTLHDEEHMLSAFEVLI 375

  Fly   490 ----------AQNESLSPYYELDGRFFDQKIREHVFRYNYTLNP-------NGVYEAI------- 530
                      :..:.|...:::|.  ||...|..: .:|..|:.       :|::..:
  Fly   376 PREIREKSTQSHLKDLLRQFKVDN--FDDATRGRM-EFNECLHILSVKHFWHGIHRTVLARLSHA 437

  Fly   531 ----KYIYTFWPD-PNNNTI--------IRD-QYINMLSDLYYRAPVDQMVKLMLE----QKVPV 577
                .|:|.|..| |:.|..        :|. .:.:.||.|:|....:::.|..:|    |:: |
  Fly   438 PATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILANKVDKSSMEYQTIQRL-V 501

  Fly   578 YMYVLNTTVEALNLPQ-----WRKYPHDIERYFLTGAPFM------DTEFFPKKEHLQRNMW 628
            .|:|.....:..|.||     |......        .|.|      ..||....|..|..:|
  Fly   502 GMWVAFARNDNPNCPQIGPTTWEALDEK--------GPQMCLNIGKQLEFIVLPESKQNRIW 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	159/582 (27%)
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	154/566 (27%)
		Aes	<117..>233	CDD:223730	56/124 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440427
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740