Protein Alignment Gli and alpha-Est2

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001262345.1
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 180/676 - (26%)
• Similarity: 270/676 - (39%)
• Gaps: 204/676 - (30%)

  Fly   112 VLAGWRE------DLQG-KQRRDSLTLERDVFVTTNYGQVQGF-KVYMYDNPDPKSFYRPYHSTV 168
            |..||.:      .|.| |.::..|:....|.:.|.||||:|. :..:||.       .||.:
  Fly     3 VQVGWPKLIKMGAQLVGHKVQQYRLSTGHTVILDTKYGQVRGLQRKTVYDK-------EPYFA-- 58

  Fly   169 DRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVRYTGATK------- 225
                     |.|||||.||..:.||:.|:....|| :|...            |..:|
  Fly    59 ---------FEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCT------------TNRSKPMQRNML 102

  Fly   226 -GIMDMDEDCLYLNVYSPKTGAGVAQK-YPVMVYIHGGEFIRGASNLFQGHILASFY----DVVV 284
             ||::..||||:||||   ..|..::| .||:|:|:||.|.:|.::   ..|.:..|    .||.
  Fly   103 LGIVEGSEDCLHLNVY---VKALKSEKPLPVIVWIYGGGFQKGEAS---RDIYSPDYFMKKPVVF 161

  Fly   285 VTLNYRLGALGFLSTGDE--NSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAG 347
            |.:||||.||||||..|.  :.|||.|:.||.|||||:..||..||||.|:|||.|..||.||..
  Fly   162 VAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVH 226

  Fly   348 LLMVAPQTRNIVRRVIAQSGSALADWALIQDK---YR-AQN---------------TSRVLGQLL 393
            ::|...|||.:..:.|.|||.||::|....|.   :| |||               .|:|..:.:
  Fly   227 VMMTTEQTRGLFHKAIMQSGCALSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQI 291

  Fly   394 GCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLT 458
             .:|:..  ::| |...|||.            .|.:|||::...|   |......|.||
  Fly   292 -AAIDQD--VIN-LDEVRSFL------------LFAFGPVIEPYET---DHCVVPKRHKD----- 332

  Fly   459 QTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNP 523
                  :.:..:..:|..:.|..:                  .:|.|..|.:|:..:
  Fly   333 ------LLSEAWGNDIPVIVGGNS------------------FEGLFSYQLVRKDPW-------- 365

  Fly   524 NGVYEAIKYIYTFWPDPNNNTII---RDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTT 585
                 |:|..:...|.....|..   :|..:..|..||:...:.:.:::.
  Fly   366 -----ALKNFHNILPREVRETSSLEGQDLLVRRLKQLYFNNEMQESMEMF--------------- 410

  Fly   586 VEALNLPQWRKYPHDIERYFL---TGAPFMDTEFF------PKKEHLQRNMWTDNDRNMSH---- 637
             ||||:...|:..||..|:.|   :.||...|..:      |.....:|.:..|..|.::|
  Fly   411 -EALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSPHFNQFRRLVCGDRIRGVAHADEL 474

  Fly   638 ---FF--------------------MQTYTNFARYGNPT-PQQVLGMHFQRAYQGEIRYLNINTT 678
               |:                    :..:|:||..|||. |:  ||.....|.|  ::...:...
  Fly   475 SYLFYNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPNCPE--LGSAKWEAVQ--LKENAVEKC 535

  Fly   679 YNSSILLNYR---QTEC-AFWTQYLP 700
            :|.|..|..|   :::| |.|..:.|
  Fly   536 FNISHDLEMRDLPESDCLAVWDTFYP 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	171/640 (27%)
alpha-Est2	NP_001262345.1	COesterase	32..523	CDD:278561	163/605 (27%)
		Aes	<117..>221	CDD:223730	50/109 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440428
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740