Protein Alignment Gli and alpha-Est8

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 610
• Identity: 159/610 - (26%)
• Similarity: 241/610 - (39%)
• Gaps: 177/610 - (29%)

  Fly   123 KQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFY-RPYHSTVDRVMGECSVFLGIPYALP 186
            |..:..|.....|...|.||:|:|.|.        :|.| ..|:|           |.|||:|.|
  Fly    21 KTNQQRLRSNDKVIADTVYGKVKGVKW--------QSIYGNNYYS-----------FEGIPFAKP 66

  Fly   187 PTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQK 251
            |..|.|||.|.....|..::......|  :|.:.....|.:.. .|||||||||:.:...  .:.
  Fly    67 PVGELRFKAPVEPEHWSDVKRCTHVRA--KPCQVNIVLKQVQG-SEDCLYLNVYTRELHP--HRP 126

  Fly   252 YPVMVYIHGGEFIRG--ASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDE--NSPGNYGILD 312
            .||:|:|:||.|..|  :.:|:....:...: ||:|.::||||||||||..||  :.|||.|:.|
  Fly   127 LPVLVWIYGGGFQMGEASRDLYSPDYIMMEH-VVLVVISYRLGALGFLSLADEELDVPGNAGLKD 190

  Fly   313 QAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWAL-- 375
            |.||||||..|.:||.||.::||:||..|||||...:|:..|.:.:..:.|..||||||.||.
  Fly   191 QVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTP 255

  Fly   376 --IQDKYR-AQ--------NTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFP 429
              |...|| ||        |...:...|..|...|..|:...:.|....::        ::..|.
  Fly   256 THINWPYRLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERHQ--------RLTMFS 312

  Fly   430 WGPVLDHNFT--------------------LP---GDDWYEGW----REKDWRFLTQTPETLIRA 467
            :||.::...|                    :|   |.:.:||.    ....|      ||.|.:.
  Fly   313 FGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKW------PELLCQL 371

  Fly   468 GKFNRNIQYMTGVTTQEAAFFVAQNESLSP----YYELDGRFFDQKIRE---------------- 512
            |                      ..|:|:|    ..|...:.|.:|:||
  Fly   372 G----------------------DCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGRKTILEY 414

  Fly   513 -HVFRYNYTLNPNGVYEAI-----------KYIYTFWPDPNNNTIIR----------DQYINMLS 555
             .:|.|.|..  :|::..:           .::|.|..|..:..|:|          ..:.:.||
  Fly   415 SDLFSYKYFW--HGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLS 477

  Fly   556 DLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKK 620
            .|:|.|...::.:...|.|          |::.|        ...:..:.::|.|.:......:|
  Fly   478 YLFYNAAAKKLKRRTAEFK----------TIKRL--------VSMVVHFAISGDPNIPMVCQDEK 524

  Fly   621 EHLQRNMW---TDNDR-----NMSH 637
            |. .|..|   :.:|:     |:||
  Fly   525 EQ-PRGAWLPISKDDKVFQCLNISH 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	157/599 (26%)
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	157/602 (26%)
		Aes	<116..>221	CDD:223730	48/107 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440425
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740