DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gli and CG10339

DIOPT Version :9

Sequence 1:	NP_476602.1	Gene:	Gli / 34927	FlyBaseID:	FBgn0001987	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	NP_611881.1	Gene:	CG10339 / 37854	FlyBaseID:	FBgn0034972	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	584	Identity:	150/584 - (25%)
Similarity:	244/584 - (41%)	Gaps:	99/584 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 FLGIPYALPPTFEGRFKPPRVH-RGWQ-LLQAVDFGPAC-----PQPVRYTGATKGIMDMD---- 231
            :|||.||    ...||:||.:. ..|: :..|..|.|.|     |...:.|.....|:..|
  Fly    58 YLGIRYA----HARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSDSSAQ 118

  Fly   232 -------EDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNY 289
                   |:||||||:.| .|......|.|:|:||.|:|..|:....:...|.....|:|||.:|
  Fly   119 DAERKYEENCLYLNVFVP-DGLPEINGYAVVVWIHSGDFSTGSPADVEPFQLVFKQKVIVVTFSY 182

  Fly   290 RLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQ 354
            ||...||.:|.|..:.||||::||:.||.||..||.||.||.|.|||.|..||..|..|.|.:.:
  Fly   183 RLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVALHMTSGE 247

  Fly   355 -TRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGN 418
             ::....:.|..||:.|   :.::..|..:.:...:.....|....:...:.||:      .:..
  Fly   248 WSKGGFHKAIIMSGNPL---STVKMPYEYEGSLDQVSSTFACPRRPTSMFIQCLK------RIDA 303

  Fly   419 AEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQ 483
            ...|..:....||||:|.           |.....:.|:...||.|.:.|.::| :..:.|||..
  Fly   304 KRLSENLPQVSWGPVVDF-----------GLSNTSYPFIENQPEILFKKGSYHR-VPVIIGVTDM 356

  Fly   484 EAAFFVAQNE---SLSPYYELDGRFFD-------QKIREHVFRYNYTLNPNGVYEAIKYIYTFWP 538
            |....:.::.   .:|| .:|:|.:.|       :.:|.:.:..||.|    :.:||.::|....
  Fly   357 EEVLTLFKDNLDTDISP-SDLEGFYTDIAVTDMHKLVRNYEWCSNYEL----ISDAINFMYANDS 416

  Fly   539 DPN----NNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEAL--NLPQWRKY 597
            |.:    |..|     |:..::.:|..|:.....| :.....||.|:......::  :||.|...
  Fly   417 DTDAKKANKHI-----ISAHTEKFYITPMQTFADL-ISNDSQVYSYLFRMRPRSVLQDLPSWISV 475

  Fly   598 PHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHF 662
            |...::.|:.|.|:|....          .|...|:.::...|..:.|||:..|||...|. :.:
  Fly   476 PKYFDQIFVWGNPYMTNSV----------DWKSTDKKIADIIMTLWANFAKTSNPTKSNVY-VKW 529

  Fly   663 QRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVI--------------GVLVPTYPP 712
            ..........|.|:.::|:..|||.::..  ||....|.::              |:::.|..|
  Fly   530 NAMTPNNDSVLLIDESFNTDNLLNNQRIN--FWRSLYPKILVFSADCCNSTFSGSGLVIATSVP 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	144/551 (26%)
CG10339	NP_611881.1	COesterase	30..560	CDD:278561	144/551 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910