Protein Alignment Gli and cel.1

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_955901.2
• Gene: cel.1 / 322481
• ZFINID: ZDB-GENE-030131-1201
• Length: 550
• Species: Danio rerio
• Alignment Length: 624
• Identity: 173/624 - (27%)
• Similarity: 268/624 - (42%)
• Gaps: 158/624 - (25%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKS----FYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPR 197
            |.|..|.|||           ||    .:| |..|          |.|||:|.||.   ||:.|.
Zfish    25 VLTEGGMVQG-----------KSRSVGLFR-YMDT----------FKGIPFAAPPK---RFEKPV 64

  Fly   198 VHRGWQ-LLQAVDFGPACPQPVRYTGATKGIMDMD----EDCLYLNVYSPKTGAGVAQKYPVMVY 257
            .|.||: :|:..|:...|.|        ..::..|    |||||||::.|: |..|:...||||:
Zfish    65 AHPGWEGVLKTTDYRKRCLQ--------LNLLATDVIGSEDCLYLNIWVPQ-GRTVSSNLPVMVF 120

  Fly   258 IHGGEFIRGASN--------LFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQA 314
            |:||.|:.|...        |:.|..:|...:|:|||.|||:|||||:||||:..|||||:.||.
Zfish   121 IYGGAFLLGGGQGANFLDNYLYDGEEMADRGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQH 185

  Fly   315 MALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDK 379
            .|:.||:.||:.|.|:.::|||||..||.||....::.|:.:.::||.|:|||.||..||:.::
Zfish   186 AAISWVHRNIKAFGGNPDNITLFGESAGAASVNFQIITPKNKGMIRRAISQSGVALCPWAISRN- 249

  Fly   380 YRAQNTSRVLGQLLGCSIESSWKLVNCLR-------TGRSFYELGNAEFSPQVGSFPWGPVLDHN 437
              .:..:..:...:||.|:|.  :.:||:       |.....:|.::..:|.|.:....||:|
Zfish   250 --PRQFAEEIATKVGCPIDSG--MADCLKRADPKAVTLAGKLKLTSSPDAPIVHNLYLSPVID-- 308

  Fly   438 FTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFV-----AQNESL-- 495
                ||            |:...||||....   .:|.|:.||...:|..|.     :.|.:|
Zfish   309 ----GD------------FIPDEPETLFGNA---ADIDYIAGVNDMDAHIFATIDIPSINNALTT 354

  Fly   496 SPYYELD------GRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINML 554
            :|..|:.      .|...|......|: .||:|              |.|..|...::...:.:.
Zfish   355 TPVEEVQALATALSRDRGQDAGIATFQ-EYTVN--------------WGDKPNKEKVKQTVVELE 404

  Fly   555 SDLYYRAPVDQMVKLMLE--QKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPF-MDTEF 616
            :|..:..|....:.|..:  :....:.|:...:......|.|....|..|..::.|.|| ....:
Zfish   405 TDYMFLVPTQAALYLHTDNAKSARTFSYLFTESSRIPVFPLWMGADHADELQYVFGKPFATPLGY 469

  Fly   617 FPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIR---------- 671
            ||:            .|::|.:.:..::|||:.|:|.             :||.:
Zfish   470 FPR------------HRDVSKYMIAYWSNFAQTGDPN-------------KGESKVPVTWPEFSN 509

  Fly   672 ----YLNINTTYNSSILLNYRQTECA-FWTQYL---PTV 702
                ||:||...|.:.:....:|... :||...   |||
Zfish   510 PGHQYLDINNKMNKNNVKQMLRTRLVYYWTTVFASYPTV 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	168/612 (27%)
cel.1	NP_955901.2	COesterase	25..517	CDD:306613	164/591 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.870