Protein Alignment Gli and Ces2i

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: XP_008758816.2
• Gene: Ces2i / 292152
• RGDID: 1565045
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 182/644 - (28%)
• Similarity: 262/644 - (40%)
• Gaps: 153/644 - (23%)

  Fly   111 GVLAGWRED--------LQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHST 167
            |.|.||...        ||....:||.:..|:    |..|||:|..|::   .|.||   ..|:
  Rat     4 GRLPGWLYVVACGLLLLLQHVHGQDSASPIRN----TQTGQVRGSFVHV---KDTKS---GVHT- 57

  Fly   168 VDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIM---- 228
                      |||||:|.||.....|.||.....|   ..|..|.:.|.....|...|...
  Rat    58 ----------FLGIPFAKPPVGPLHFAPPEDPEPW---SGVRDGTSQPDMCLQTDIMKEDFIKEM 109

  Fly   229 -------DMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVT 286
                   .|.|||||||:|:| ..|......||||:||||..:.|::::.....||:..::|:|.
  Rat   110 KLTMHPTPMSEDCLYLNIYTP-AHAREGSNLPVMVWIHGGGLVLGSASMNVASTLAATEEIVIVA 173

  Fly   287 LNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMV 351
            :.||||.|||.|||||::.||:|.|||..||.||..||.:|.|:...:|:||..|||.|....:|
  Rat   174 IQYRLGILGFFSTGDEHARGNWGYLDQVAALCWVQQNIAYFGGNHGKVTIFGVSAGGTSVSSHVV 238

  Fly   352 APQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRV----LGQLLGCSIESSWKLVNCLRTGRS 412
            :|.::.:....|.|||.||.. .||.|      ||.|    :..|.||....|..|:.||| .:|
  Rat   239 SPMSKGLFHGAIMQSGVALLP-DLISD------TSEVVYKTVANLSGCEASDSEALIRCLR-AKS 295

  Fly   413 FYEL--GNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQ 475
            ..|:  .|..|.                .:||        ..|.:||.:.|:.|:.:|.|: .:.
  Rat   296 KQEILAINQVFK----------------MIPG--------VVDGKFLPKHPQELLASGDFH-PVP 335

  Fly   476 YMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFR---------------YNYTLNPNG 525
            .:.||.|.|....|.....|                :|:.:               ....|.|
  Rat   336 SIIGVNTDECGLGVPMFMGL----------------DHIIKKITRDTLPTVLKSTAAQMMLPP-- 382

  Fly   526 VYEAIKYIY-TFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEAL 589
              |.|..|. .:..|..:...:::|:..||.|..:..|..::......| .|||.|      |..
  Rat   383 --ECIDLIMEEYMGDTEDPETLQEQFKEMLGDFMFVIPALEVAHFQRSQ-APVYFY------EFQ 438

  Fly   590 NLPQWRKY--------PHDIERYFLTGAPF--MDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYT 644
            :||.:.|.        .|..:..|:..:.|  |:.:...::|.|:|.:            |:.:.
  Rat   439 HLPSFIKQVRPSHVKADHGDDILFVFSSYFWGMNFDITEEEELLKRRV------------MKYWA 491

  Fly   645 NFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVI 703
            ||||.|||..:.   :.:........:||.:||.......|..|:.:  |||:.||..|
  Rat   492 NFARNGNPNSED---LPYWPVLDHNEQYLQLNTQPAVGRALKARRLQ--FWTKTLPQKI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	167/603 (28%)
Ces2i	XP_008758816.2	COesterase	30..537	CDD:395084	168/608 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336204
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840