Protein Alignment Gli and Ces2g

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 174/628 - (27%)
• Similarity: 259/628 - (41%)
• Gaps: 148/628 - (23%)

  Fly   120 LQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYA 184
            :||:...:|..:.     .|:.|||||...:      .|.|....|:           |||||:|
  Rat    24 VQGQHSPESSPIR-----NTHTGQVQGKLTH------SKDFKSGVHT-----------FLGIPFA 66

  Fly   185 LPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVRYTGATKGI---------MDMDEDCLYLNV 239
            ..|....||.||.....|. :.........|||.||..  .:|:         :.|.|||||||:
  Rat    67 KAPVGPLRFAPPEAPEPWSGVRDGTSQSNICPQNVRMN--MEGLKEMKLTLPPVSMSEDCLYLNI 129

  Fly   240 YSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENS 304
            |:| ..|......||||:||||....|.::::.|.:||:..||||||:.||||.|||.||||.::
  Rat   130 YAP-AHAHEGSHLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQYRLGVLGFFSTGDHHA 193

  Fly   305 PGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSA 369
            .||:|.|||..|||||..||..|.|:.:.:|:||..|||.|....:|:|.::.:..|.|.:||.|
  Rat   194 RGNWGYLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGGLSVSSHVVSPMSKGLFHRAIMESGVA 258

  Fly   370 LADWALIQDKYRAQNTSRVLGQLL----GCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPW 430
            |....:.       |.|.::.|::    ||.......||:||| |:|..::
  Rat   259 LMPGTIF-------NFSEMVYQMVVKLSGCEAMDPESLVHCLR-GKSEEQI-------------- 301

  Fly   431 GPVLDHNF-TLPGDDWYEGWREKDWRFLTQTPETLIRAGKFN--------RNIQY---------- 476
             .|:...| .:|.        ..|..||...|:.|:.:..|:        .|.:|
  Rat   302 -TVISKEFQMIPA--------VVDGEFLPNHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGS 357

  Fly   477 ---MTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWP 538
               :.|:|.:....|:   :..:|...|.....|..:.|::          |..|
  Rat   358 AQTIKGITRENLQAFL---KDTAPQMMLPPECSDLLMEEYM----------GDIE---------- 399

  Fly   539 DPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALN--LPQWRKYPHDI 601
            ||..   ::.|:..|:.|..:..|..|:.:.. ....|||.|........|.  .|...|..|..
  Rat   400 DPQT---LQAQFTEMMEDFMFVIPSLQVARFQ-RSHAPVYFYEFQHQSSFLKDIRPPHVKADHGD 460

  Fly   602 ERYFLTGAPFMDTEFFPKKEHLQRNMW------TDNDRNMSHFFMQTYTNFARYGNPTPQQVLGM 660
            |      .||:...||          |      |:.::.::...|:.:.||||||||...   .:
  Rat   461 E------VPFVFGSFF----------WGMKLNLTEGEKLLNRRMMKYWANFARYGNPNSN---SL 506

  Fly   661 HFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVI 703
            .:...:..:.:||.:||......:...|:.:  |||:.||..|
  Rat   507 PYWPVFDYDEQYLQLNTQPAVGRIQKARKLQ--FWTKTLPQKI 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	165/604 (27%)
Ces2g	NP_001099645.1	COesterase	31..539	CDD:278561	166/611 (27%)
		Aes	<129..>232	CDD:223730	51/103 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336207
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740