Protein Alignment Gli and cest-9.2

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 146/710 - (20%)
• Similarity: 242/710 - (34%)
• Gaps: 210/710 - (29%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201
            :.|:||:|:|...:..||                  ....:|..:|:|.||..:.||.||:....
 Worm    24 IETSYGRVRGITEWSDDN------------------NHKYMFKSVPFAKPPIGKLRFAPPQYPDS 70

  Fly   202 WQ-LLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIR 265
            |. :|.|..:.|||......|...:  ..:.|||||:|:::.:  ..:..|..|:||.|||.:..
 Worm    71 WSGVLDASKYSPACLSNSSTTSTPQ--EHVSEDCLYINIFTSE--KCLRSKCAVIVYFHGGAYNG 131

  Fly   266 GASNLFQGHILASFY---DVVVVTLNYRLGALGFLSTGDENSPG-----NYGILDQAMALRWVYD 322
            .::.:|..:.:...|   ||::.....|||..|.|..|    |.     |..:.|...||.:|::
 Worm   132 DSATMFPDNFILERYVAEDVILAIPGVRLGVFGQLYFG----PSALLTENLFMFDAVQALDFVHN 192

  Fly   323 NIEFFNGDRNSITLFGPGAGGASAGLL----MVAPQTRNIVRRVIAQSGSALADW--------AL 375
            .|..|.||...:|:.|..:||.....|    .|.|..: :.:::|..||:.:..:        .:
 Worm   193 EIPNFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDLK-LFQQIIVLSGTGMFGFYDLLVDNSFI 256

  Fly   376 IQDKY------RAQNTSRVLGQLLGC--------------SIESSWKLV-NCLRTGRSFYELGNA 419
            |.:|.      :.:.|...:.::|.|              .:|..:||. ..|..|..|.||..
 Worm   257 ISEKLGCFNGTQEERTDANIAEILECMRQIDGHEIVGMQKHMEDVYKLTFKSLLRGAPFMELNG- 320

  Fly   420 EFSPQVGSFPWGPVLDHNFTLP-----GDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTG 479
                ::..|       .|.|.|     |...||                      |...::....
 Worm   321 ----KIEKF-------RNSTSPRNAIFGTTEYE----------------------FRNEVERYLY 352

  Fly   480 VTTQ----EAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGV---YEAIKY----- 532
            :||.    |....|||:             ||.::.:::   :..:|.:.|   ..|..:
 Worm   353 ITTTFLDFENPVAVAQH-------------FDDELMQNM---DTMINGDAVSIFVSAAAFSSAMA 401

  Fly   533 -----IYTF----WPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMY---VLNTT 585
                 :|.|    ||           |...:||:.|...:.:.|....:..:....|   ::|.|
 Worm   402 NAGADVYLFETRQWP-----------YSFHVSDMQYFIGIHREVLHTHDMDILDSFYSKLLVNFT 455

  Fly   586 VEALNLPQWRKYPHDIERYF------LTG-APFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTY 643
            ......|:|.....:...|.      ..| .|.|...:..|:.........|.|||::..
 Worm   456 KTGAPSPEWNSLEPEKMNYLELRVDTRNGKGPVMLEGYHDKEVSFWYGDMMDYDRNITKM----- 515

  Fly   644 TNFARYGNPTPQQVLGMHFQRAYQGEI------RYLNINTTYNSSILLNYRQTECAFWTQYLPTV 702
                |.....|::..|:..|..|...|      .:.|..|..|.|...|...|..|   ||:...
 Worm   516 ----RQSKGLPRENQGVESQLKYWSSIVEPRTTAHANNATQENISTSTNVLFTSTA---QYISRE 573

  Fly   703 IGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICC-----IMWRNAKRQSD 757
            .    ....|..:.||                 |:||:.:|:..     |..|..:|:.:
 Worm   574 F----KNSTPILQQWW-----------------FYLIIALVVMIFVLIFISLRKPRREEE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	134/641 (21%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	117/564 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900