Protein Alignment Gli and Ces1c

DIOPT Version :10

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: XP_006255234.2
• Gene: Ces1c / 24346
• RGDID: 2571
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 183/599 - (30%)
• Similarity: 279/599 - (46%)
• Gaps: 98/599 - (16%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201
            |.|..|:|.|..|.:      :.|.:|           .:||||:|:|.||....||.||.....
  Rat    28 VDTTKGKVLGKYVSL------EGFTQP-----------VAVFLGVPFAKPPLGSLRFAPPEPAEP 75

  Fly   202 WQLLQ-AVDFGPACPQ---------PVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQ--KYPV 254
            |..:: ...:.|.|.|         .:..||.....::..|||||||:|||   |.:.:  :.||
  Rat    76 WSFVKNTTTYPPMCSQDGVVGKLLADMLSTGKENIPLEFSEDCLYLNIYSP---ADLTKNSRLPV 137

  Fly   255 MVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRW 319
            ||:||||..|.|.::.:.|..|::..:|||||:.||||..|..|||||:|.||:..|||..||||
  Rat   138 MVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRW 202

  Fly   320 VYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQN 384
            |.|||..|.|:.:|:|:||..|||.|..:|:::|..:|:..|.|::||..|   ....||...|.
  Rat   203 VQDNIANFGGNPDSVTIFGESAGGVSVSVLVLSPLAKNLFHRAISESGVVL---TTNLDKKNTQA 264

  Fly   385 TSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGW 449
            .::::..|.||:..||..:|.|||. ::..||  .|.:.::.:.....|:| ...||
  Rat   265 VAQMIATLSGCNNTSSAAMVQCLRQ-KTEAEL--LELTVKLDNTSMSTVID-GVVLP-------- 317

  Fly   450 REKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFV--AQNESLSPYYELDGRFFDQKIRE 512
                     :|||.::....|| .:.|:.|...||..:.:  .....||     :||..::....
  Rat   318 ---------KTPEEILTEKSFN-TVPYIVGFNKQEFGWIIPTMMGNLLS-----EGRMNEKMASS 367

  Fly   513 HVFRYNYTLN-PNGVYEAI--KYIYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQK 574
            .:.|::..|| ...|..||  ||: ....||...   ::..::|.||:::..|...|.:.:.:..
  Rat   368 LLRRFSPNLNISESVIPAIIEKYL-RGTDDPAKK---KELLLDMFSDVFFGIPAVLMSRSLRDAG 428

  Fly   575 VPVYMYVLNTTVEALN--LPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSH 637
            .|.|||........::  .||..:..|..|.:.:.|.||:       ||..     ::.:.|:|.
  Rat   429 APTYMYEFQYRPSFVSDQRPQTVQGDHGDEIFSVFGTPFL-------KEGA-----SEEETNLSK 481

  Fly   638 FFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTV 702
            ..|:.:.||||.|||..:   |:.....|..:..||.|..|...:..|  :..|.||||:
  Rat   482 LVMKFWANFARNGNPNGE---GLPHWPEYDQKEGYLQIGATTQQAQKL--KGEEVAFWTE----- 536

  Fly   703 IGVLVPTYPPTTEY 716
               |:...||.||:
  Rat   537 ---LLAKNPPQTEH 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	137..695	CDD:395084	175/576 (30%)
		PRK13335	818..>918	CDD:139494
Ces1c	XP_006255234.2	COesterase	24..534	CDD:395084	175/576 (30%)