Protein Alignment Gli and Cel

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_058693.2
• Gene: Cel / 24254
• RGDID: 2331
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 172/606 - (28%)
• Similarity: 261/606 - (43%)
• Gaps: 133/606 - (21%)

  Fly   177 VFLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVY 240
            :|.|||:|...|.|.    |:.|.||| .|:|.||...|.|.......|.|    .|||||||::
  Rat    50 IFKGIPFATAKTLEN----PQRHPGWQGTLKATDFKKRCLQATITQDDTYG----QEDCLYLNIW 106

  Fly   241 SPKTGAGVAQKYPVMVYIHGGEFIRGASN--------LFQGHILASFYDVVVVTLNYRLGALGFL 297
            .|:....|:...||||:|:||.|:.|:..        |:.|..:|:..:|:|||.|||:|.||||
  Rat   107 VPQGRKQVSHDLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFL 171

  Fly   298 STGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRV 362
            ||||.|.|||:|:.||.||:.||..||..|.||.::||:||..||.||..|..::|..:.::||.
  Rat   172 STGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRA 236

  Fly   363 IAQSGSALADWALIQDKYRAQNT---SRVLGQLLGCSIESSWKLVNCLR-------TGRSFYELG 417
            |:|||.||:.||:      .:|.   ::.:.:.:||..|.:.|:..||:       |......|.
  Rat   237 ISQSGVALSPWAI------QENPLFWAKTIAKKVGCPTEDTAKMAGCLKITDPRALTLAYRLPLK 295

  Fly   418 NAEFSPQVGSFPWGPVLDHNFTLPGD--DWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGV 480
            :.|: |.|....:.||:|.:| :|.|  :.|:.                      ..:|.|:.|:
  Rat   296 SQEY-PIVHYLAFIPVVDGDF-IPDDPINLYDN----------------------AADIDYLAGI 336

  Fly   481 TTQEAAFFVAQNESLSPYYELDGRFF-----------DQKIREHVFRYNYTL-NPNGVYEAIK-- 531
            .                  ::||..|           .|.:.|..|   |.| :.:.|.:.:|
  Rat   337 N------------------DMDGHLFATVDVPAIDKAKQDVTEEDF---YRLVSGHTVAKGLKGT 380

  Fly   532 ----YIYT-FWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQ------KVPVYMYVLNTT 585
                .||| .|....:...::...:...:|:.:..|.:    :.|.|      ....|.|:.:..
  Rat   381 QATFDIYTESWAQDPSQENMKKTVVAFETDILFLIPTE----MALAQHRAHAKSAKTYSYLFSHP 441

  Fly   586 VEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYG 650
            ......|:|....|..:..::.|.||..    |.....|       ||.:|...:..:||||:.|
  Rat   442 SRMPIYPKWMGADHADDLQYVFGKPFAT----PLGYRAQ-------DRTVSKAMIAYWTNFAKSG 495

  Fly   651 NPT-PQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNY-RQTECAFWT---QYLPTVIGVLVP-- 708
            :|. ....:..|:.........||:||....|:.:..: |:....||.   :.||||:|...|
  Rat   496 DPNMGNSPVPTHWYPYTTENGNYLDINKKITSTSMKEHLREKFLKFWAVTFEMLPTVVGDHTPPE 560

  Fly   709 ------TYPPTTEYWWEPKEP 723
                  ..|||.:....|..|
  Rat   561 DDSEAAPVPPTDDSQVVPVPP 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	159/565 (28%)
Cel	NP_058693.2	COesterase	26..542	CDD:278561	159/565 (28%)
		Aes	<118..>247	CDD:223730	62/128 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..612		7/29 (24%)
		4 X 11 AA tandem repeats, O-glycosylated region	556..599		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870