Protein Alignment Gli and cest-31

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 159/594 - (26%)
• Similarity: 244/594 - (41%)
• Gaps: 131/594 - (22%)

  Fly   157 PKSFYRPYHSTVDRVMG--------ECSVFLGIPYALPPTFEGRFKPPRVHRGW-QLLQAVDFGP 212
            ||......:||...|.|        |...:||||||.||....|||.|.....| :......:||
 Worm    10 PKPLLNVLNSTCGPVQGNLYRHGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGP 74

  Fly   213 AC-PQPVRYTGATKGIMDMDED--CLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGH 274
            .| |..:.|........|:.::  ||.|||:.|:.....:.|:|||::||||.|...||..:..:
 Worm    75 RCPPSGMLYENLQLPNTDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFIHGGGFELSASKDYCDY 139

  Fly   275 ILAS---FYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITL 336
            .|:.   ..||:|||:|||:||||||:|||::..||:|:.|..:||:||..:|..|.||..::||
 Worm   140 SLSGTLPLKDVIVVTVNYRVGALGFLTTGDDSCRGNFGLWDLTLALKWVSTHISSFGGDPKNVTL 204

  Fly   337 FGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSW 401
            ||..||...|.||.::|.:|::..::|..||||...:|:..::.:|
 Worm   205 FGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQA------------------- 250

  Fly   402 KLVNCLRTGRS--FYELGNAEFSPQVGSFPWGPVL-----------DHNF--TLPGDDWYEGWRE 451
             || |:...||  |...|:||......:.|...:|           |.:|  .|.||.:
 Worm   251 -LV-CMEYARSRGFSGSGSAELLEFFENLPIEKLLEKTGLKHTVSIDLSFAPNLDGDFF------ 307

  Fly   452 KDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQE---AAFFVAQNESLSPYYELDGRF------FD 507
                     |:.|....:..|....:.|:...|   .||             .||.|      |.
 Worm   308 ---------PKPLEELRRETRKKPVIVGMMEDEGLITAF-------------ADGDFTTCEENFK 350

  Fly   508 QKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLE 572
            ::: |..:|.:...||..|.:.|...||.:.|.:...    :.::.:....|.|.|....:.:..
 Worm   351 RRV-ESEYRGDVVENPENVQKNIMNFYTNYCDESEER----KLVDYIGHSVYNAGVLLSAESLAR 410

  Fly   573 QKVPVYMYVLNTTVEALNLPQW--------------RKYPHDIERYFLTGAPFMDTEFFPKKEHL 623
            ....||.||.:.         |              :...|..|..::.|......  |...|
 Worm   411 AGNCVYFYVFDF---------WNPDGFGPVGSIVPFKGAAHCSELRYIIGEGVYSK--FDANE-- 462

  Fly   624 QRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYR 688
                   .|..|..:....:||||:||||   .:.|:.....|....|:.:|::| :|.:..:::
 Worm   463 -------KDLKMMEYMTTMFTNFAKYGNP---NIPGVTNWETYTEGSRHFHIDST-DSEMKDSFQ 516

  Fly   689 QTECAFWTQ 697
            :..|.|..|
 Worm   517 ENRCQFLKQ 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	157/590 (27%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	155/583 (27%)
		Aes	<112..>211	CDD:223730	46/98 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810